5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
- CAS No.
- 312753-53-0
- Chemical Name:
- 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
- Synonyms
- 5,6-diethyl-2,3-dihydro-1H-inden-2-amine;5-ethyl-2,3-dihydro-1H-inden-2-amine;Indacaterol InterMediate;Indacaterol Impurity 6 HCl;Indacetrol;Indacaterol int2;5,6-diethylindan-1-one;Indacaterol Impurity 10;Indacaterol Intermediate 1;Indacaterol Impurity 17 HCl
- CBNumber:
- CB32128688
- Molecular Formula:
- C13H20ClN
- Molecular Weight:
- 225.76
- MOL File:
- 312753-53-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/8 17:00:39
| Melting point | >250 ºC |
|---|---|
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White |
| CAS DataBase Reference | 312753-53-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H312-H315-H302-H332 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501 |
5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride Chemical Properties,Uses,Production
Uses
5,6-Diethyl-2,3-dihydro-1H-inden-2-amine Hydrochloride acts as a reagent in the synthetic preparation of quinolinone compounds and it’s formulations in combination with corticosteroids for treatment of airway disorder.
Synthesis
Preparation 4-5,6-Diethyl-indan-2-ylamine Hydrochloride 5,6-Diethyl-3-oxime-1H-indene-1,2(3H)-dione (4.5 g) is added to a mixture of acetic acid (150 mL), and concentrated sulphuric acid (4.5 mL). Pd/C5% (1.5 g) is added, the reaction mixture degassed with nitrogen, and hydrogenated for 5 hours. The catalyst is then removed by filtration, the pH brought to pH 10 with 4M NaOH, and the solution extracted with chloroform. The organic phase is dried with magnesium sulphate, and the solvent removed in vacuo. The residue is redisolved in a minimum amount of ether, and HCl saturated ether added. The white precipitate is filtered and dried to yield the HCl salt of 5,6-diethyl-indan-2-ylamine, a compound of formula XVII where R3, R4 and R7 are H, R5 and R6 are each CH3CH2-, R30 is hydrogen and n is 1. 5,6-Diethyl-indan-2-ylamine Hydrochloride.
5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| MANVI BIOPHARMA PVT LTD, | +91-9951015911 +91-9951015911 | Hyderabad, India | 86 | 58 | Inquiry |
| Neugen Labs | +91-8133254502 +91-8133254502 | Karnataka, India | 195 | 58 | Inquiry |
| CHEMAZON LABORATORIES | +91 9848551964 | Hyderabad, India | 1320 | 58 | Inquiry |
| Sanovi Pharmaceuticals Pvt Ltd | +91-9900284769 +91-9900284769 | Karnataka, India | 42 | 58 | Inquiry |
| Apiqule Pharmachem LLP | +91-9537957857 +91-9904897541 | Gujarat, India | 21 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Jinan Million Pharmaceutical Co., Ltd | 0531-68659554 +8613031714605 | China | 192 | 58 | Inquiry |
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