Methyltrienolone
- CAS No.
- 965-93-5
- Chemical Name:
- Methyltrienolone
- Synonyms
- METRIBOLONE;R1881;Methytrienolone;METHYLTRIENOLONE(R-1881);RU-1881;trienoL;NSC 92858;Methyltrienone;11-triene-3-one;METHYLTRIENOLONE
- CBNumber:
- CB3221633
- Molecular Formula:
- C19H24O2
- Molecular Weight:
- 284.39
- MOL File:
- 965-93-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/14 16:41:43
| Melting point | 170° |
|---|---|
| alpha | D20 -58.7° (c = 0.5 in ethanol) |
| Boiling point | 485.9±45.0 °C(Predicted) |
| Density | 1.17±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: ≥10mg/mL |
| pka | 14.79±0.40(Predicted) |
| form | powder |
| color | light yellow to yellow |
| optical activity | [α]/D -48 to -68° |
| InChI | InChI=1/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/s3 |
| InChIKey | CCCIJQPRIXGQOE-XWSJACJDSA-N |
| SMILES | [C@@]12([H])CC[C@@](O)(C)[C@@]1(C)C=CC1=C3CCC(=O)C=C3CC[C@@]21[H] |&1:0,4,7,21,r| |
| CAS DataBase Reference | 965-93-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P305+P351+P338 |
| WGK Germany | 3 |
| DEA Controlled Substances | CSCN: 4000 CSA SCH: Schedule III NARC: No |
Methyltrienolone Chemical Properties,Uses,Production
Description
Methyltrienolone, also called metribolone, is an orally active anabolic-androgen steroid being a 17α-alkylated nandrolone (19-nortestosterone) derivative. It is not sold as a prescription drug or a dietary supplement due to its strong androgenic side effects and liver toxicity. However, it is often used as the reference point for in vitro biological activity for biochemical studies. It can bind strongly to the androgen receptor and can be used as an affinity label of the androgen receptor in the prostate and prostatic tumors.
Chemical Properties
Pale Yellow Solid
Uses
Methyltrienolone is a synthetic derivative of testosterone that is used in the medical field as an androgen and anabolic agent. It has been used to treat breast cancer, prostate cancer, and other cancers that are sensitive to hormones.
Definition
ChEBI: Methyltrienolone, also known as 7beta-hydroxy-17-methylestra-4,9,11-trien-3-one, is a synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors. It has a role as an androgen. It is an anabolic androgenic steroid, a 17beta-hydroxy steroid and a 3-oxo steroid. It derives from a hydride of an estrane.
References
https://en.wikipedia.org/wiki/Metribolone
https://www.drugbank.ca/drugs/DB02998
https://pubchem.ncbi.nlm.nih.gov/compound/Methyltrienolone
Kazlauskas R. (2010) Designer Steroids. In: Thieme D., Hemmersbach P. (eds) Doping in Sports: Biochemical Principles, Effects and Analysis. Handbook of Experimental Pharmacology, vol 195. Springer, Berlin, Heidelberg
Methyltrienolone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Zhuzhou New Peptides Tech Co.,Ltd. | +86-18073326374 +86-18073326374 | China | 145 | 58 | Inquiry |
| qingdao future trading Co., Ltd | +86-13335044410 +86-13335044410 | China | 110 | 58 | Inquiry |
| Shandong Hanjiang Chemical Co., Ltd | +86-0533-2066820 +8618369939125 | China | 975 | 58 | Inquiry |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | China | 973 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | China | 12459 | 58 | Inquiry |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | China | 616 | 58 | Inquiry |
| zhuzhou dingcheng meihei comestic co.,ltd | +8618873369619 | China | 260 | 58 | Inquiry |
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