Chinese english Japanese Germany Korea

Tolbutamide-d9

Tolbutamide-d9 Structure
CAS No.
1219794-57-6
Chemical Name:
Tolbutamide-d9
Synonyms
Mobenol-d9;Artozin-d9;Artosin-d9;[2H9]-Tolbutamide;Tolylsulfonylbutylurea-d9;Tolbutamide-d9 Solution, 100ppm;3-(p-Tolyl-4-sulfonyl)-1-butylurea-d9;1-(Butyl-3-(p-tolyl- sulfonyl)urea-d9;N-Butyl-N'-(4-Methylphenylsulfonyl)urea-d9;N-[(ButylaMino-d9)carbonyl]-4-MethylbenzenesulfonaMide
CBNumber:
CB32512331
Molecular Formula:
C12H18N2O3S
Molecular Weight:
270.35
MOL File:
1219794-57-6.mol
Modify Date:
2024/7/2 8:55:06
Request For Quotation

Tolbutamide-d9 Properties

Melting point 108-111°C
storage temp. Refrigerator
solubility DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:1): 0.14 mg/ml
form A solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
NFPA 704
0
2 0

Tolbutamide-d9 Chemical Properties,Uses,Production

Description

Tolbutamide-d9 is intended for use as an internal standard for the quantification of tolbutamide by GC- or LC-MS. Tolbutamide is an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 (IC50 = 4.9 μM). It is selective for SUR1/Kir6.2 over SUR2A/Kir6.2 and SUR2B/Kir6.2 channels (IC50s = 85 and 88 μM, respectively). Tolbutamide increases glucose-induced insulin secretion and calcium influx in isolated mouse pancreatic islets. In vivo, tolbutamide (80 mg/kg) reduces blood glucose levels in a mouse model of diabetes induced by streptozotocin (STZ; ). Formulations containing tolbutamide have been used in the treatment of type 2 diabetes.

Chemical Properties

White Solid

Uses

Labelled Tolbutamide (T535150). An antidiabetic, used as a hypoglycemic agent in veterinary medicine.

Tolbutamide-d9 Preparation Products And Raw materials

Raw materials

Preparation Products

Tolbutamide-d9 Suppliers

Global( 19)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 China 18488 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 China 8740 58 Inquiry
ChengDu SinoStandards Bio-Tech Co.,Ltd. ， 028-83243028 19136088901 China 5359 58 Inquiry
Alta Scientific Co., Ltd. 022-6537-8550 15522853686 China 4515 55 Inquiry
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 China 56057 58 Inquiry
Nanjing Haolv Biotechnology Co.,Ltd 025-84622273 02584622273; China 3022 58 Inquiry
Toronto Research Chemicals +1 (416) 665-9696 Canada 6088 71 Inquiry
Supplier Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd 58
CLEARSYNTH LABS LTD. 58
Changzhou Bojia Biomedical Technology Co., Ltd. 58
Cayman Chemical Company 81
Shanghai Yifei Biotechnology Co. , Ltd. 58
ChengDu SinoStandards Bio-Tech Co.,Ltd. ， 58
Alta Scientific Co., Ltd. 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
Nanjing Haolv Biotechnology Co.,Ltd 58
Toronto Research Chemicals 71

1219794-57-6(Tolbutamide-d9)Related Search:

TOLAZAMIDE Tolbutamide Impurity 5 4-Carboxytolbutamide Methyl Ester TOLBUTAMIDE Tolbutamide 4-Carboxy Ethyl Ester
4-Hydroxytolbutamide
chevron_left

1of2

chevron_right
1-(Butyl-3-(p-tolyl- sulfonyl)urea-d9 3-(p-Tolyl-4-sulfonyl)-1-butylurea-d9 Artosin-d9 Artozin-d9 Mobenol-d9 N-[(ButylaMino-d9)carbonyl]-4-MethylbenzenesulfonaMide N-Butyl-N'-(4-Methylphenylsulfonyl)urea-d9 Tolylsulfonylbutylurea-d9 1-(4-methylphenyl)sulfonyl-3-(1,1,2,2,3,3,4,4,4-nonadeuteriobutyl)urea Tolbutamide-d9 Solution, 100ppm [2H9]-Tolbutamide 1219794-57-6 C12H9D9N2O3S Aromatics Intermediates & Fine Chemicals Isotope Labelled Compounds Pharmaceuticals Sulfur & Selenium Compounds