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4-Hydroxytolbutamide

4-Hydroxytolbutamide Structure
CAS No.
5719-85-7
Chemical Name:
4-Hydroxytolbutamide
Synonyms
HYDROXY TOLBUTAMIDE;Tolbutamide Hydroxy;4-HYDROXYTOLBUTAMIDE;Tolbutamide Impurity 4;hydroxymethyltolbutamide;HydroxyMethylcarbutaMide;HydroxyMethylcarbutaMide Impurity;4-Hydroxytolbutamide solution ;4-Hydroxytolbutamide Solution, 100ppm;1-Butyl-3-(p-hydroxyMethylphenyl)sulfonylurea
CBNumber:
CB1258804
Molecular Formula:
C12H18N2O4S
Molecular Weight:
286.35
MOL File:
5719-85-7.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:22

4-Hydroxytolbutamide Properties

Melting point 100-102 °C
Density 1.268±0.06 g/cm3(Predicted)
Flash point 2℃
storage temp. 2-8°C
solubility ethanol: 12 mg/mL
form Solid
pka 4.96±0.10(Predicted)
color white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H302+H312+H332-H319
Precautionary statements  P210-P261-P302+P352+P312-P304+P340+P312-P337+P313-P403+P235
Hazard Codes  F,Xn
Risk Statements  11-20/21/22-36
Safety Statements  16-36/37-24/25
RIDADR  UN 1648 3 / PGII
WGK Germany  3
HS Code  29350090

4-Hydroxytolbutamide price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) UC160 4-Hydroxytolbutamide ≥98% (HPLC) 5719-85-7 5MG ₹84229.33 2022-06-14 Buy
Sigma-Aldrich(India) UC160 4-Hydroxytolbutamide ≥98% (HPLC) 5719-85-7 10MG ₹153097.98 2022-06-14 Buy
Product number Packaging Price Buy
UC160 5MG ₹84229.33 Buy
UC160 10MG ₹153097.98 Buy

4-Hydroxytolbutamide Chemical Properties,Uses,Production

Description

4-hydroxy Tolbutamide is a cytochrome P450 2C8 (CYP2C8) and CYP2C9 metabolite of tolbutamide, a first-generation potassium channel blocker. Tolbutamide 4-hydroxylation is an often used probe reaction in the pharmaceutical industry for the characterization of CYP2C8 and CYP2C9 involvement in the metabolism of clinical drugs.

Chemical Properties

White Solid

Uses

4-Hydroxytolbutamide has been used as a standard to assay the fungal biotransformation of tolbutamide to 4′-hydroxytolbutamide.

Definition

ChEBI: A urea that consists of 1-butylurea having a 4-hydroxymethylbenzenesulfonyl group attached at the 3-position.

4-Hydroxytolbutamide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 78)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-87569266 15319487004 China 4088 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Artis Biotech Co. Ltd. 19138486554 18582380095 China 2754 58 Inquiry
Shanghai Xiushi Biomedical Co., LTD 15021598081,571034478; 15021598081 China 4527 58 Inquiry
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 China 29803 58 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28118 58 Inquiry
SHANGHAI ZZBIO CO., LTD. 18019219489 19921389125 China 12064 58 Inquiry
4-HYDROXYTOLBUTAMIDE HYDROXY TOLBUTAMIDE N-(BUTYLAMINOCARBONYL)-4-HYDROXYMETHYLBENZENESULFONAMIDE N-(Butylamnocarbonyl)-4-hydroxymethylbenzenesulfonamide hydroxymethyltolbutamide 4-Hydroxytolbutamide,N-(Butylaminocarbonyl)-4-hydroxymethylbenzenesulfonamide 1-Butyl-3-(p-hydroxyMethylphenyl)sulfonylurea HydroxyMethylcarbutaMide 4-Hydroxytolbutamide solution N-(butylcarbamoyl)-4-(hydroxymethyl)benzenesulfonamide 1-butyl-3-[4-(hydroxymethyl)phenyl]sulfonylurea 4-Hydroxytolbutamide Solution, 100ppm Tolbutamide Hydroxy Benzenesulfonamide, N-[(butylamino)carbonyl]-4-(hydroxymethyl)- Tolbutamide Impurity 4 HydroxyMethylcarbutaMide Impurity 5719-85-7 C12H18N2O4S HU - HZ Analytical Chromatography Product Catalog Alphabetic Analytical Standards Various Metabolites and Impurities Metabolites Metabolites & Impurities