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Apremilast

Apremilast Structure
CAS No.
1384967-20-7
Chemical Name:
Apremilast
Synonyms
Apste impurity 15;Apremilast O-Desethyl;Apremilast Impurity L;Apremilast impurity HS093315;(S)-N-(2-(1-(3-Hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide;Acetamide, N-[2,3-dihydro-2-[(1S)-1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-1H-isoindol-4-yl]-;N-[2,3-Dihydro-2-[(1S)-1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-1H-isoindol-4-yl]acetamide (Apremilast Impurity)
CBNumber:
CB33386054
Molecular Formula:
C20H20N2O7S
Molecular Weight:
432.45
MOL File:
1384967-20-7.mol
Modify Date:
2023/5/15 10:43:58

Apremilast Properties

Boiling point 781.7±60.0 °C(Predicted)
Density 1.485±0.06 g/cm3(Predicted)
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 9.59±0.10(Predicted)
color Light Yellow

Apremilast Chemical Properties,Uses,Production

Uses

O3-Desethyl Apremilast is a related compound of?Apremilast, an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis.?Apremilast is also an anti-inflammatory agent. Apremilast Impurity 6

Apremilast Preparation Products And Raw materials

Raw materials

Preparation Products

Apremilast Impurity L Apremilast impurity HS093315 (S)-N-(2-(1-(3-Hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Acetamide, N-[2,3-dihydro-2-[(1S)-1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-1H-isoindol-4-yl]- Apste impurity 15 N-[2,3-Dihydro-2-[(1S)-1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-1H-isoindol-4-yl]acetamide (Apremilast Impurity) Apremilast O-Desethyl 1384967-20-7