Syringic acid
- CAS No.
- 530-57-4
- Chemical Name:
- Syringic acid
- Synonyms
- 4-HYDROXY-3,5-DIMETHOXYBENZOIC ACID;Syringate;Cedar acid;Benzoic acid, 4-hydroxy-3,5-dimethoxy-;cedaracid;Suringic acid;Syringle acid;RARECHEM AL BE 0102;SYRA;NSC 2129
- CBNumber:
- CB3381988
- Molecular Formula:
- C9H10O5
- Molecular Weight:
- 198.17
- MOL File:
- 530-57-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/8/25 17:13:35
| Melting point | 205-209 °C (lit.) |
|---|---|
| Boiling point | 192-193°C 14mm |
| Density | 1.2539 (rough estimate) |
| refractive index | 1.4570 (estimate) |
| Flash point | 192-193°C/14mm |
| storage temp. | Store below +30°C. |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 4.33±0.10(Predicted) |
| form | Powder |
| color | Grayish-beige to light brown |
| Water Solubility | 5780 mg/L (25 ºC) |
| BRN | 2115262 |
| Stability | Stable. Incompatible with strong bases, strong oxidizing agents. |
| InChIKey | JMSVCTWVEWCHDZ-UHFFFAOYSA-N |
| LogP | 1.040 |
| CAS DataBase Reference | 530-57-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzoic acid, 4-hydroxy-3,5-dimethoxy-(530-57-4) |
| EPA Substance Registry System | Syringic acid (530-57-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DH2090000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29189090 | |||||||||
| NFPA 704 |
|
Syringic acid price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S6881 | Syringic acid ≥95% (HPLC) | 530-57-4 | 5G | ₹6819.75 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S6881 | Syringic acid ≥95% (HPLC) | 530-57-4 | 10G | ₹7967.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S6881 | Syringic acid ≥95% (HPLC) | 530-57-4 | 25G | ₹11647.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S6881 | Syringic acid ≥95% (HPLC) | 530-57-4 | 100G | ₹25016.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.22161 | 4-Hydroxy-3,5-dimethoxybenzoic acid for synthesis | 530-57-4 | 10G | ₹4470 | 2022-06-14 | Buy |
Syringic acid Chemical Properties,Uses,Production
Description
Syringic acid is a naturally occurring O-methylated phenolic acid that can be enzymatically degraded by some bacteria as a source of methane or methanol. It is also a component of phenolic extracts from various plants that have antioxidant and prooxidant activities. Syringic acid has been shown to inhibit aldose reductase (IC50 = 213 μg/ml), proteasome activity, and cancer cell proliferation. Phenolic extracts containing syringic acid have been shown to inhibit α-amylase and α-glucosidase activities and reduce lipid peroxidation in vitro.
Chemical Properties
light brown powder
Uses
Syringic Acid is used in biological studies for electron transfer from plant phenolates to carotenoid radical cations with antioxidant interaction entering the Marcus theory inverted region.
Definition
ChEBI: A dimethoxybenzene that is 3,5-dimethyl ether derivative of gallic acid.
Purification Methods
Recrystallise syringic acid from H2O using charcoal [Bogert & Coyne J Am Chem Soc 51 571 1929, Anderson & Nabenhauer J Am Chem Soc 48 3001 1926.] The methyl ester has m 107o (from MeOH), the 4-acetyl derivative has m 190o and the 4-benzoyl derivative has m 229-232o. [Hahn & Wassmuth Chem Ber 67 2050 1934, UV: Lemon J Am Chem Soc 69 2998 1947 and Pearl & Beyer J Am Chem Soc 72 1743 1950, Beilstein 10 IV 1995.]
Syringic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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