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(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride

CAS No.: 88046-01-9

Chemical Name:: (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride

Synonyms: N-[4-[[(amino iminomethyl) thio]-methyl]-2-thiazolyl]-guanidine dihydrochloride (FMT-II);Famotidine Impurity 13;Iso Thiourea Hcl. (ITU);Famotidine Impurity H DiHCl;Famotidine EP Impurity H HCL;Famotidine Related Compound h;Famotidine EP Impurity H DiHCl;Famotidine Isothiourea Impurity;[2-[(Diaminomethylidene)amino]thiaz;Famotidine EP Impurity H Dihydrochloride

CBNumber:: CB3511561

Molecular Formula:: C6H11ClN6S2

Molecular Weight:: 266.77

MOL File:: 88046-01-9.mol

MSDS File:: SDS

Modify Date:: 2024/5/24 11:39:31

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(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Properties

Melting point	>188oC (dec.)
storage temp.	Refrigerator
solubility	DMSO (Sparingly), Methanol (Slightly)
form	Solid
color	White to Off-White
PH	3.89 at 1000g/L
InChI	InChI=1S/C6H10N6S2.ClH/c7-4(8)12-6-11-3(2-14-6)1-13-5(9)10;/h2H,1H2,(H3,9,10)(H4,7,8,11,12);1H
InChIKey	DMXJVYCDETXZRR-UHFFFAOYSA-N
SMILES	N(C1SC=C(CSC(N)=N)N=1)C(N)=N.Cl
LogP	1 at 30℃ and pH3.89

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H412-H302-H332-H402-H317
Precautionary statements	P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P312-P330-P501-P273-P501-P261-P271-P304+P340-P312

(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Chemical Properties,Uses,Production

Uses

Famotidine intermediate.

Definition

Famotidine EP Impurity H is chemically (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride. It is also known as Famotidine Isothiourea Impurity . Famotidine EP Impurity H can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Famotidine.

(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Preparation Products And Raw materials

Raw materials

Amidinothiourea 1,3-Dichloroacetone

Preparation Products

3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER

(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Suppliers

Global( 146)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
RIDDHI PHARMA	+91 7874046933	Gujarat, India	43	58	Inquiry
Neugen Labs	+91-8133254502 +91-8133254502	Karnataka, India	195	58	Inquiry
Rivashaa Agrotech Biopharma Pvt. Ltd.	+91-26463395 +91-7926462688	Gujarat, India	1615	58	Inquiry
Ralington Pharma	+91-7948911722 +91-9687771722	Gujarat, India	1350	58	Inquiry
Vaasavaa Pharmaceuticals (P) Ltd	+91-2172357177 +91-9493758494	Telangana, India	20	58	Inquiry
Nakoda Chemicals Ltd	+91-9848218200 +91-9848218200	Telangana, India	15	58	Inquiry
Sibram Pharmaceutical	+91-8655777550 +91-8655777550	Maharashtra, India	244	58	Inquiry
Orchev Pharma Pvt Ltd	+91-2812365732 +91-2812365731	Gujarat, India	7	58	Inquiry
OCEAN TRADING CORPORATION	+91(22) 24921669	New Delhi, India	6211	58	Inquiry
Anant Pharmaceuticals Pvt. ltd	+91 8550986868	Maharashtra, India	736	58	Inquiry

Supplier	Advantage
RIDDHI PHARMA	58
Neugen Labs	58
Rivashaa Agrotech Biopharma Pvt. Ltd.	58
Ralington Pharma	58
Vaasavaa Pharmaceuticals (P) Ltd	58
Nakoda Chemicals Ltd	58
Sibram Pharmaceutical	58
Orchev Pharma Pvt Ltd	58
OCEAN TRADING CORPORATION	58
Anant Pharmaceuticals Pvt. ltd	58

88046-01-9((S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride)Related Search:

N-DesaMinosulfonyl-N-cyano FaMotidine Famotidine EP Impurity A [3-[[[2-(DiaMinoMethyleneaMino)-4-thiazolyl]Methyl]thio]propionyl]sulfaMide Hydrochloride (FaMotidine IMpurity) Acetonitrile Benzothiazole

Methanol Methyl acrylate Methylparaben Tetramethylthiourea Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT)

N-Aminothiourea Glycine 2-Methyl-4-isothiazolin-3-one Sulfamide FAMOTIDINE RELATED COMPOUND B

2-(4-(CHLOROMETHYL)THIAZOL-2-YL)GUANIDINE 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoyl propanamide Bis[(2-guanidino-4-thiazolyl)methyl]disulfide

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Carbamimidothioic acid [2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl ester dihydrochloride N-(4-(((AMINOIMINOMETHYL)THIO)METHYL)-2-THIAZOLYL)GUANIDINE S-[(2-Guanidino-4-thiazolyl)methyl]isothiourea 2HCl S-[(2-Guanidino-4-thiazolyl)methyl]isothiourea dihydrochloride N-[4-(Aminoiminomethyl)Thiomethyl-2-Thiazolyl]Guanidine Dihydrochloride N"-[4-(Aminoiminomethyl)thiomethyl-2-thiazolyl]guanidine2HCl Carbamimidothioic acid(2-aminoiminomethyl)amino)-4-Thiazolyl)methyl ester Famotidine EP Impurity H DiHCl Famotidine Impurity H DiHCl (2-((diaminomethylene)amino)thiazol-4-yl)methyl carbamimidothioate diHCl Carbamimidothioic Acid [2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl Ester DiHCl S-(2-Guanidino-4-thiazolyl)methylisothiour Famotidine EP Impurity H Dihydrochloride Famotidine Impurity 13 Famotidine Isothiourea Impurity [2-[(Diaminomethylidene)amino]thiaz Famotidine Related Compound h (2-guanidinothiazol-4-yl)methyl carbamimidothioate dihydrochloride amino(methylsulfanyl)methaniminium chloride (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochlor... N-[4-[[(amino iminomethyl) thio]-methyl]-2-thiazolyl]-guanidine dihydrochloride (FMT-II) (2-Guanidinothiazol-4-yl)methyl carbamimidothioate dihydrochloride (Famotidine Impurity) Famotidine Impurity 13 (Famotidine EP Impurity H Dihydrochloride) Iso Thiourea Hcl. (ITU) Famotidine EP Impurity H as Dihydrochloride ISO THIOUREA [(S)-((2-GUANIDINO-4-THIAZOLYL) METHYLISOTHIOUREA DIHYDROCHLORIDE](ITU) Famotidine EP Impurity H HCL ((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride 88046-01-9 C6H12Cl2N6S2 C6H10N6S22HCl Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds