4-(Difluoromethoxy)nitrobenzene

4-(Difluoromethoxy)nitrobenzene Structure
CAS No.
1544-86-1
Chemical Name:
4-(Difluoromethoxy)nitrobenzene
Synonyms
BUTTPARK 45\10-48;α,α-Difluoro-p-nitroanisole;Anisole,α,α-difluoro-p-nitro-;4-(DIFLUOROMETHOXY)NITROBENZENE;p-Nitrophenyldifluoromethylether;Difluoromethyl4-nitrophenylether;1-(DIFLUOROMETHOXY)-4-NITROBENZENE;4-(Difluoromethoxy)nitrobenzene98%;4-(Difluoromethoxy)nitrobenzen, 98%;4-NITRO-ALPHA,ALPHA-DIFLUOROANISOLE
CBNumber:
CB3714535
Molecular Formula:
C7H5F2NO3
Molecular Weight:
189.12
MOL File:
1544-86-1.mol
Modify Date:
2023/4/23 13:52:06

4-(Difluoromethoxy)nitrobenzene Properties

Melting point 37-40 °C (lit.)
Boiling point 108 °C
Density 1.384±0.06 g/cm3(Predicted)
Flash point >230 °F
storage temp. 2-8°C
form powder to lump
color Light yellow to Brown to Dark green
FreezingPoint 31.0 to 34.0 ℃
CAS DataBase Reference 1544-86-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501-P280a-P304+P340-P405-P501a-P261-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36/37
RIDADR  3276
WGK Germany  3
HazardClass  IRRITANT
HS Code  29049090
NFPA 704
1
2 0

4-(Difluoromethoxy)nitrobenzene price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) D2601 4-(Difluoromethoxy)nitrobenzene min. 98.0 % 1544-86-1 5G ₹5200 2022-05-26 Buy
Product number Packaging Price Buy
D2601 5G ₹5200 Buy

4-(Difluoromethoxy)nitrobenzene Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Crystal.

Uses

4-(Difluoromethoxy)nitrobenzene is an industrial chemical that can be used to make 4-fluoro-3-pyridinol (F3P), a compound that has potential as a new drug for the treatment of cancer. The synthesis of F3P begins with the reaction of 4-(difluoromethoxy)nitrobenzene and potassium hydroxide in methanol, which yields 4-fluoro-3-hydroxypyridine. This product is then reacted with ammonia gas and pyridine to yield F3P. The final step involves heating the product at high temperature with nitric acid, which yields nitrobenztriazole.

General Description

4-(Difluoromethoxy)nitrobenzene (1-(difluoromethoxy)-4-nitrobenzene) can be synthesized by reacting 4-nitrophenol with KOH, water and methanol.

4-(Difluoromethoxy)nitrobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 106)Suppliers
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Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
BUTTPARK 45\10-48 Anisole,α,α-difluoro-p-nitro- Benzene,1-(difluoromethoxy)-4-nitro- Difluoromethyl4-nitrophenylether p-Nitrophenyldifluoromethylether 1-(DIFLUOROMETHOXY)-4-NITROBENZENE 4-(DIFLUOROMETHOXY)NITROBENZENE 4-NITRO-ALPHA,ALPHA-DIFLUOROANISOLE α,α-Difluoro-p-nitroanisole 4-(Difluoromethoxy)nitrobenzen, 98% 4-(Difluoromethoxy)nitrobenzene98% Difluoromethyl 4-nitrophenyl ether, alpha,alpha-Difluoro-4-nitroanisole, 1-(Difluoromethoxy)-4-nitrobenzene alpha,alpha-Difluoro-p-nitroanisole 1544-86-1 F2CHOC6H4NO2 Building Blocks Nitro Compounds Organic Building Blocks Nitrogen Compounds Building Blocks Chemical Synthesis Nitro Compounds Nitrogen Compounds Organic Building Blocks