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4-(Difluoromethoxy)nitrobenzene

4-(Difluoromethoxy)nitrobenzene Structure
  • ₹5200
  • Product name: 4-(Difluoromethoxy)nitrobenzene
  • CAS: 1544-86-1
  • MF: C7H5F2NO3
  • MW: 189.12
  • EINECS:
  • MDL Number:MFCD00085009
  • Synonyms:BUTTPARK 45\10-48;Anisole,α,α-difluoro-p-nitro- ;Benzene,1-(difluoromethoxy)-4-nitro- ;Difluoromethyl4-nitrophenylether ;p-Nitrophenyldifluoromethylether ;1-(DIFLUOROMETHOXY)-4-NITROBENZENE;4-(DIFLUOROMETHOXY)NITROBENZENE;4-NITRO-ALPHA,ALPHA-DIFLUOROANISOLE
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Brand

  • TCI Chemicals (India)

Package

  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberD2601
  • Product description4-(Difluoromethoxy)nitrobenzene min. 98.0 %
  • Packaging5G
  • Price₹5200
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D2601 4-(Difluoromethoxy)nitrobenzene min. 98.0 % 5G ₹5200 2022-05-26 Buy

Properties

Melting point :37-40 °C (lit.)
Boiling point :108 °C
Density :1.384±0.06 g/cm3(Predicted)
Flash point :>230 °F
storage temp. :2-8°C
form :powder to lump
color :Light yellow to Brown to Dark green
FreezingPoint :31.0 to 34.0 ℃
CAS DataBase Reference :1544-86-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

4-(Difluoromethoxy)nitrobenzene is an industrial chemical that can be used to make 4-fluoro-3-pyridinol (F3P), a compound that has potential as a new drug for the treatment of cancer. The synthesis of F3P begins with the reaction of 4-(difluoromethoxy)nitrobenzene and potassium hydroxide in methanol, which yields 4-fluoro-3-hydroxypyridine. This product is then reacted with ammonia gas and pyridine to yield F3P. The final step involves heating the product at high temperature with nitric acid, which yields nitrobenztriazole.

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