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MURISTERONE A

MURISTERONE A Structure
CAS No.
38778-30-2
Chemical Name:
MURISTERONE A
Synonyms
MURA;Muristerone;MURISTERONE A;Ecdysonic sterol;MURISTERONE A(P);MURISTERONE A USP/EP/BP;MURISTERONE A, IPOMOEA SPP;5B, 7-CHOLESTENE-2B,3B,5A,11A,14,20,22-HEPTOL-6-ONE;2B,3B,5A,11A,14,20,22-HEPTAHYDROXY-5B-7-CHOLESTEN-6-ONE;2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one
CBNumber:
CB3781616
Molecular Formula:
C27H44O8
Molecular Weight:
496.63
MOL File:
38778-30-2.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
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MURISTERONE A Properties

Boiling point 707.2±60.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility Soluble in DMSO
form solid
pka 11.78±0.70(Predicted)
color white

SAFETY

Risk and Safety Statements

WGK Germany  3

MURISTERONE A Chemical Properties,Uses,Production

Description

Muristerone A is a natural analog of 20-hydroxyecdysone . It is an agonist of the ecdysteroid receptor (Kd = 1 nM), a nuclear receptor that heterodimerizes with a retinoid X receptor ortholog and regulates arthropod development. Muristerone A is used as an agonist in ecdysone-inducible gene expression systems in mammalian cells. However, it inhibits apoptosis in the human colon carcinoma cell line RKO by inducing the upregulation of Bcl-xL, suggesting limitations in its use in certain types of studies.

Uses

Muristerone A, an ecdysteroid, is widely used for the induction of ecdysteroid-dependent transcription in mammalian cells.

Biological Activity

Ecdysone analog that acts as an inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells.

MURISTERONE A Preparation Products And Raw materials

Raw materials

Preparation Products

MURISTERONE A Suppliers

Global( 79)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMAZON LABORATORIES +91 9848551964 Hyderabad, India 1320 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24639 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23963 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9707 58 Inquiry
NINGBO JL NEW MATERIAL CO.,LTD 0574-88552218 18969899212 China 700 58 Inquiry
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 China 8141 58 Inquiry
Beijing Lebo Biotechnology Co., Ltd. 010-50934026 CHINA 6057 58 Inquiry
Supplier Advantage
CHEMAZON LABORATORIES 58
Dideu Industries Group Limited 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
Aladdin Scientific 58
TargetMol Chemicals Inc. 58
Cayman Chemical Company 81
Shanghai EFE Biological Technology Co., Ltd. 58
NINGBO JL NEW MATERIAL CO.,LTD 58
MedBioPharmaceutical Technology Inc 58
Beijing Lebo Biotechnology Co., Ltd. 58

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2B,3B,5A,11A,14,20,22-HEPTAHYDROXY-5B-7-CHOLESTEN-6-ONE 2BETA,3BETA,5ALPHA,11ALPHA,14,20,22-HEPTAHYDROXY-5BETA,7-CHOLESTEN-6-ONE 2BETA,3BETA,5BETA,11ALPHA,14ALPHA,20R,22R-HEPTAHYDROXYCHOLEST-7-EN-6-ONE 5B, 7-CHOLESTENE-2B,3B,5A,11A,14,20,22-HEPTOL-6-ONE 5BETA,7-CHOLESTENE-2BETA,3BETA,5ALPHA,11ALPHA,14,20,22-HEPTOL-6-ONE MurA, 2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one (22R)-2β,3β,5,11α,14,20,22-Heptahydroxy-5β-cholest-7-en-6-one Ecdysonic sterol Muristerone Cholest-7-en-6-one, 2,3,5,11,14,20,22-heptahydroxy-, (2beta,3beta,5beta,11alpha,22R)- (2β,3β,5β,11α,22R)-2,3,5,11,14,20,22-Heptahydroxycholest-7-en-6-one MURISTERONE A(P) (2beta,3beta,5beta,11alpha,22R)-2,3,5,11,14,20,22-Heptahydroxy-cholest-7-en-6-one MURISTERONE A MURISTERONE A, IPOMOEA SPP MURA 2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one MURISTERONE A USP/EP/BP Cholest-7-en-6-one, 2,3,5,11,14,20,22-heptahydroxy-, (2β,3β,5β,11α,22R)- 38778-30-2 BioChemical Apoptosis and Cell Cycle Cell Biology Apoptosis Inducers Cell Signaling and Neuroscience Miscellaneous Natural Products