trofosfamide

trofosfamide  Structure
CAS No.
22089-22-1
Chemical Name:
trofosfamide
Synonyms
A-4828;Ccris 4442;Brn 0532530;Asta Z 4828;trofosfamide;TROPHOSPHAMIDE;Trofosfamide,Bacterial,Inhibitor,inhibit;2H-1,3,2-Oxazaphosphorin-2-amine, N,N,3-tris(2-chloroethyl)tetrahydro-, 2-oxide (9ci);3-(2-Chloroethyl)-2-(bis(2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine 2-oxide;3-(2-Chloroethyl)-2-(bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide
CBNumber:
CB3877124
Molecular Formula:
C9H18Cl3N2O2P
Molecular Weight:
323.58
MOL File:
22089-22-1.mol
Modify Date:
2023/6/8 9:02:51

trofosfamide Properties

Melting point 47-49°C
alpha D25 -28.6° (c = 2 in CH3OH)
Boiling point 104°C
Density 1.35±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMF: 50mg/mL; DMSO: 30mg/mL; Ethanol: 50mg/mL; PBS (pH 7.2): 10mg/mL
form A crystalline solid
pka -0.46±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS06
Signal word  Danger
Hazard statements  H372-H301-H413-H340-H360-H350
Precautionary statements  P260-P264-P270-P314-P501-P264-P270-P301+P310-P321-P330-P405-P501
Toxicity LD50 i.p. in mice: 212 mg/kg (Brock, Potel)
NFPA 704
0
2 0

trofosfamide Chemical Properties,Uses,Production

Chemical Properties

Off-White Low Melting Solid

Uses

Antineoplastic; one derivative

Safety Profile

Poison by intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by ingestion. Human mutation data reported. Human systemic effects by unspecified routes: hematuria, leukopenia, and thrombocytopenia. When heated to decomposition it emits very toxic fumes of Cl-, NOx, and POx.

trofosfamide Preparation Products And Raw materials

Raw materials

Preparation Products

trofosfamide Suppliers

Global( 37)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9708 58 Inquiry
Shaanxi Dideu Newmaterial Co., Ltd. 029-63373950 15353716720 China 10011 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24017 58 Inquiry
Shanghai New Union Textra Import & Export Co., Ltd +861-348-227-9455 China 2752 60 Inquiry
CHEMICAL LAND21 82- 2 -783 - 8063 South Korea 6315 74 Inquiry
trofosfamide TROPHOSPHAMIDE 2-(Bis(2-chloroethyl)amino)-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide 2H-1,3,2-Oxazaphosphorin-2-amine, N,N,3-tris(2-chloroethyl)tetrahydro-, 2-oxide (9ci) 2H-1,3,2-Oxazaphosphorine, 2-(bis(2-chloroethyl)amino)-3-(2-chloroethyl)tetrahydro-, 2-oxide 3-(2-Chloroethyl)-2-(bis(2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine 2-oxide 3-(2-Chloroethyl)-2-(bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide A-4828 Asta Z 4828 Brn 0532530 Ccris 4442 Trofosfamide,Bacterial,Inhibitor,inhibit 22089-22-1 C9H18Cl3N2O2P C9H14D4Cl3N2O2P Heterocycles Intermediates & Fine Chemicals Isotope Labelled Compounds Pharmaceuticals