L-Tyrosine Ethyl Ester Hydrochloride
- CAS No.
- 4089-07-0
- Chemical Name:
- L-Tyrosine Ethyl Ester Hydrochloride
- Synonyms
- TEE;Tyr-Oet Hcl;H-TYR-OET HCL;L-Tyr-OEt.HCL;H-L-Tyr-OEt*HCl;TYROSINE-OET HCL;L-Tyrosine ethyl est;L-TYROSINE ETHYL ESTER HCL;Ethyl L-tyrosite hydrochloride;tyrosineethylesterhydrochloride
- CBNumber:
- CB4125992
- Molecular Formula:
- C11H16ClNO3
- Molecular Weight:
- 245.7
- MOL File:
- 4089-07-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/3 12:01:51
| Melting point | 166-170 °C |
|---|---|
| alpha | [α]D20 +26～+30° (c=5, C2H5OH) |
| refractive index | -6.5 ° (C=2, H2O) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | Soluble in water (3.685e+005 mg/L @ 25°C (est.)). |
| BRN | 4725904 |
| InChIKey | BQULAXAVRFIAHN-PPHPATTJSA-N |
| LogP | 1.060 (est) |
| CAS DataBase Reference | 4089-07-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-37/39-26 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | YP2580000 | |||||||||
| HS Code | 29225090 | |||||||||
| NFPA 704 |
|
L-Tyrosine Ethyl Ester Hydrochloride price More Price(2)
L-Tyrosine Ethyl Ester Hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White to off-white microcrystalline powder
Uses
L-Tyrosine Ethyl Ester Hydrochloride is used as a medical and organic intermediate and as an important amino protective agent. It is also used to introduce t-Boc protect gene.
Application
Papain is also used for synthesizing poly(L-tyrosine) and poly(L-glutamic acid) using L-tyrosine ethyl ester hydrochloride and L-glutamic acid diethyl ester hydrochloride as the substrates, respectively. The protease-catalyzed copolymerization of amino acids is first achieved by papain using L-glutamic acid ester and various amino acid esters as substrates.
A mixture of L-tyrosine ethyl ester hydrochloride, the appropriate acid anhydri-des, triethylamine and dry tetrahydrofuran, was warmed for an hour in an atmosphere of nitrogen. After removing the amine salt, Ic and Id became crystalline on standing overnight in the cold.
Preparation
synthesis of L-Tyrosine Ethyl Ester Hydrochloride: Esterification of 25 g. ol L-tyrosine (0.014 mole) with ethanolic hydrogen chloride gave 24.1 g. of L-tyrosine ethyl ester hydrochloride (80%). Liberation of the ester by slurrying the hydrochloride in chloroform rollowed by the addition of chloroform saturated with ammonia, removal of the ammonium chloride by filtration and evaporation of the chloroform gave 19.4 g. of L-tyrosine ethyl ester (67%), m.p. 106-108 ° .
L-Tyrosine Ethyl Ester Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| chakrachem Lifesciences | +91 9902744663 | Hyderabad, India | 451 | 58 | Inquiry |
| TEADUS PHARMA PRIVATE LIMITED | +91-9740077663 +91-9740077663 | Telangana, India | 242 | 58 | Inquiry |
| SV CHEM INTERMEDITES PRIVATE LIMITED | +91-9940629423 +91-9940629423 | Tamil Nadu, India | 202 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| ALS INDIA LIFE SCIENCES | +91-8977036379 +91-8977036379 | Hyderabad, India | 1879 | 58 | Inquiry |
| ASM Organics | 91-9866122393 | Andhra Pradesh, India | 1188 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| chakrachem Lifesciences | 58 |
| TEADUS PHARMA PRIVATE LIMITED | 58 |
| SV CHEM INTERMEDITES PRIVATE LIMITED | 58 |
| JSK Chemicals | 58 |
| ALS INDIA LIFE SCIENCES | 58 |
| ASM Organics | 58 |
| CHEMSWORTH | 30 |
| A.J Chemicals | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |