cannabigerol
- CAS No.
- 25654-31-3
- Chemical Name:
- cannabigerol
- Synonyms
- cannabigerol;Anaerobically;Cannabigerol(CBG);Cannabigerol (CRM);Cannabigerol (7CI);Cannabigerol solution;Cannabigerol (exempt preparation);(E)-2-(3,7-DiMethyl-2,6-octadienyl)-5-pentylresorc;Cannabigerol (CBG) Standard@1000 μg/mL in Methanol;(E)-2-(3,7-Dimethyl-2,6-octadienyl)-5-pentylresorcinol
- CBNumber:
- CB41304730
- Molecular Formula:
- C21H32O2
- Molecular Weight:
- 316.48
- MOL File:
- 25654-31-3.mol
- Modify Date:
- 2024/3/27 16:59:26
| Melting point | 49-50 °C |
|---|---|
| Boiling point | 470.4±40.0 °C(Predicted) |
| Density | 0.987±0.06 g/cm3(Predicted) |
| Flash point | 9℃ |
| storage temp. | -20°C |
| solubility | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
| form | White to off-white powder. |
| pka | 9.71±0.40(Predicted) |
| InChI | InChI=1S/C21H32O2/c1-5-6-7-11-18-14-20(22)19(21(23)15-18)13-12-17(4)10-8-9-16(2)3/h9,12,14-15,22-23H,5-8,10-11,13H2,1-4H3/b17-12+ |
| InChIKey | QXACEHWTBCFNSA-SFQUDFHCSA-N |
| SMILES | C1(O)=CC(CCCCC)=CC(O)=C1C/C=C(\C)/CC/C=C(/C)\C |
| LogP | 7.470 (est) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H301+H311+H331-H370 | |||||||||
| Precautionary statements | P210-P260-P280-P301+P310-P311 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 1 | |||||||||
| HS Code | 9999999999 | |||||||||
| NFPA 704 |
|
cannabigerol Chemical Properties,Uses,Production
Description
Cannabigerol (CRM) (Item No. 20164) is a certified reference material categorized as a phytocannabinoid. This product is intended for research and forensic applications.
Uses
Cannabigerol is a partial agonist of CB2 and CB1 receptors (Ki values are 337 and 440 nM respectively). Cannabigerol also exhibits α2-adrenoceptor agonist activity (EC50 = 0.2 nM in mouse brain membra nes).
Definition
ChEBI: A natural product found in Cannabis sativa and Helichrysum species.
benefits
Cannabigerol (CBG) works to fight inflammation, pain, nausea and works to slow the proliferation of cancer cells. Research has shown it also significantly reduces intraocular eye pressure caused by glaucoma. Strains high in CBG will be beneficial treating conditions such as inflammatory bowel disease, Crohn's disease, and cancer.
General Description
A non-psychoactive cannabinoid found in Cannabis, Cannabigerol (CBG) reportedly has efficacy for medical conditions such as glaucoma and inflammatory bowel disease. This Certified Spiking Solution? is suitable for cannabigerol testing methods by HPLC, GC/MS or LC-MS/MS for forensic analysis, clinical toxicology, urine drug testing, and Cannabis potency or impurity profiling testing applications. Cerilliant solution Certified Reference Materials (CRMs) of cannabinoids are supplied in a convenient, quantitative, US DEA-exempt solution format and with TK#s for Canadian customers.
Mechanism of action
Cannabigerol shares a similar mechanism of action with the cannabinoid cannabidiol, since it binds itself weakly to CB1R and CB2R and, in addition to blocking CB1R, antagonizes 5-HT1A receptor, activates alpha (2) adrenoceptors, and is a modulator of endocannabinoid signaling. CBG acts as a strong α2-adrenoceptor agonist (EC50?=?0.2?nM), while it is only a moderate 5-HT1AR competitive antagonist, and at high concentrations (10?μM), it antagonizes [35S] guanosine 5′-O-[gamma-thio]triphosphate (GTPγS) binding in mouse brain membranes stimulated with AEA or CP-55940[1].
References
[1] Fabrizio Calapai. “Pharmacological Aspects and Biological Effects of Cannabigerol and Its Synthetic Derivatives.” Evidence-based Complementary and Alternative Medicine (2022): 3336516.
cannabigerol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Taizhou Blazer Biomedical Technology Co., Ltd. | 0523-86112008 13915404123 | China | 88 | 58 | Inquiry |
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 | China | 3000 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
| Xiamen Work-For-World Medicine Co.,Ltd. | +undefined15921822462 | China | 213 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21675 | 55 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3424 | 58 | Inquiry |
| Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 | China | 3148 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
25654-31-3(cannabigerol)Related Search:
1of3
chevron_right