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Cyclopropanecarboxaldehyde

Cyclopropanecarboxaldehyde Structure
CAS No.
1489-69-6
Chemical Name:
Cyclopropanecarboxaldehyde
Synonyms
Cyclopropanecarbaldehyde;Formylcyclopropane;Cyclopropylmethanal;Cyclopropylcarboxaldehyde;1-Cyclopropanecarbaldehyde;Cyclopropanecarboxyaldehyde;Cyclopropane-1-carbaldehyde;opropanecarbaL;RARECHEM AK ML 0578;Cyclopropanecarboxal
CBNumber:
CB4132338
Molecular Formula:
C4H6O
Molecular Weight:
70.09
MOL File:
1489-69-6.mol
MSDS File:
SDS
Modify Date:
2024/4/24 17:21:45

Cyclopropanecarboxaldehyde Properties

Boiling point 98-101 °C (lit.)
Density 0.938 g/mL at 25 °C (lit.)
refractive index n20/D 1.4298(lit.)
Flash point 45 °F
storage temp. 2-8°C
solubility soluble in Chloroform
form clear liquid
color Colorless to Light orange to Yellow
Water Solubility Soluble in water.
Sensitive Air Sensitive
BRN 906781
Stability Volatile
InChIKey JMYVMOUINOAAPA-UHFFFAOYSA-N
CAS DataBase Reference 1489-69-6(CAS DataBase Reference)
NIST Chemistry Reference Cyclopropanecarboxaldehyde(1489-69-6)
EPA Substance Registry System Cyclopropanecarboxaldehyde (1489-69-6)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS05
Signal word  Danger
Hazard statements  H225-H314
Precautionary statements  P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
Hazard Codes  F,C
Risk Statements  11-34
Safety Statements  16-26-36/37/39-45
RIDADR  UN 2924 3/PG 2
WGK Germany  3
RTECS  GZ1005000
TSCA  Yes
HazardClass  3
PackingGroup  II
HS Code  29122990
NFPA 704
3
3 0

Cyclopropanecarboxaldehyde price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 272213 Cyclopropanecarboxaldehyde 98% 1489-69-6 1G ₹1890 2022-06-14 Buy
Sigma-Aldrich(India) 272213 Cyclopropanecarboxaldehyde 98% 1489-69-6 5G ₹7510 2022-06-14 Buy
ALFA India ALF-L14931-06 Cyclopropanecarboxaldehyde, 98% 1489-69-6 5g ₹5885 2022-05-26 Buy
ALFA India ALF-L14931-03 Cyclopropanecarboxaldehyde, 98% 1489-69-6 1g ₹2676 2022-05-26 Buy
TCI Chemicals (India) C1707 Cyclopropanecarboxaldehyde min. 98.0 % 1489-69-6 1G ₹2900 2022-05-26 Buy
Product number Packaging Price Buy
272213 1G ₹1890 Buy
272213 5G ₹7510 Buy
ALF-L14931-06 5g ₹5885 Buy
ALF-L14931-03 1g ₹2676 Buy
C1707 1G ₹2900 Buy

Cyclopropanecarboxaldehyde Chemical Properties,Uses,Production

Chemical Properties

clear colorless liquid

Uses

Cyclopropanecarboxaldehyde reacts with Grignard or organolithium reagents to give the expected secondary alcohols. These are susceptible to ring opening in the presence of HBr, providing stereoselective access to homoallylic bromides. It is also used in the synthesis of eta(2)-enonenickel complexes by reacting with [Ni(cod)(2)] (cod = 1,5-cyclooctadiene) and PBu(3) and to prepare a cyclopropylidene tetralone which underwent an enantioselective palladium-catalyzed [3+2] TMM cycloaddition providing a chiral spiro-fused cyclopentene.

Application

Cyclopropanecarboxaldehyde is a reagent in the preparation of N-alkylphenylalaninamides of pyridinylphenyland oxobipyridinylamines as human GPR 142 agonists for potential use as anti-diabetic agents and the cytochrome P 450 inhibition.

Preparation

Cyclopropanecarboxaldehyde is prepared by reaction of cyclopropylmethanol. The reaction needs reagent pyridinium chlorochromate and solvent CH2Cl2 with other condition of ambient temperature for 3 hours. The yield is about 60%.

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