Cyclopropyl carbinol
- CAS No.
- 2516-33-8
- Chemical Name:
- Cyclopropyl carbinol
- Synonyms
- CYCLOPROPYLMETHANOL;CYCLOPROPANEMETHANOL;CPMO;CP-CARBINOL;(HYDROXYMETHYL)CYCLOPROPANE;CPC-OL;Cyclopropylmethane;RARECHEM AK ML 0580;CYCLOPROPYL CARBINOL;CYCLPOPROPANEMETHANOL
- CBNumber:
- CB1254806
- Molecular Formula:
- C4H8O
- Molecular Weight:
- 72.11
- MOL File:
- 2516-33-8.mol
- Modify Date:
- 2023/12/26 11:30:52
Melting point | -60 °C |
---|---|
Boiling point | 123-124 °C738 mm Hg(lit.) |
Density | 0.89 g/mL at 25 °C(lit.) |
refractive index |
n |
Flash point | 95 °F |
storage temp. | Flammables area |
solubility | Chloroform, Ethyl Acetate |
pka | 15.10±0.10(Predicted) |
form | Liquid |
color | Clear colorless |
Specific Gravity | 0.890 |
Water Solubility | miscible |
BRN | 1846846 |
InChIKey | GUDMZGLFZNLYEY-UHFFFAOYSA-N |
CAS DataBase Reference | 2516-33-8(CAS DataBase Reference) |
NIST Chemistry Reference | Cyclopropyl carbinol(2516-33-8) |
EPA Substance Registry System | Cyclopropanemethanol (2516-33-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02,GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H226-H302-H319 | |||||||||
Precautionary statements | P210-P301+P312+P330-P305+P351+P338 | |||||||||
Hazard Codes | Xn,Xi,C,F | |||||||||
Risk Statements | 10-22-36-34 | |||||||||
Safety Statements | 16-26-36-45-36/37/39 | |||||||||
RIDADR | UN 1987 3/PG 3 | |||||||||
WGK Germany | 1 | |||||||||
RTECS | GZ2212250 | |||||||||
Hazard Note | Irritant | |||||||||
TSCA | Yes | |||||||||
HazardClass | 3 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29061990 | |||||||||
NFPA 704 |
|
Cyclopropyl carbinol price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 482099 | Cyclopropanemethanol ≥99.5% | 2516-33-8 | 25ML | ₹15728.73 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 482099 | Cyclopropanemethanol ≥99.5% | 2516-33-8 | 250ML | ₹25644.43 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 482099 | Cyclopropanemethanol ≥99.5% | 2516-33-8 | 1L | ₹52836.83 | 2022-06-14 | Buy |
TCI Chemicals (India) | C0982 | Cyclopropanemethanol min. 98.0 % | 2516-33-8 | 5ML | ₹1800 | 2022-05-26 | Buy |
TCI Chemicals (India) | C0982 | Cyclopropanemethanol min. 98.0 % | 2516-33-8 | 25ML | ₹5600 | 2022-05-26 | Buy |
Cyclopropyl carbinol Chemical Properties,Uses,Production
Chemical Properties
Clear colorless liquid
Uses
Cyclopropylmethanol used to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A, inhibitors against phosphodiesterase 3 (PDE3). Also used in the synthesis of benzodiazapin-2-ones
Preparation
The preparation of Cyclopropyl carbinol is as follows:A 1L three-necked flask was charged with 100 g (1mol) of methyl cyclopropanoate. 57g (1.5mol) of sodium borohydride, 500 mL of methanol, and then cooled to 2°C, 66.67g (0.5mol) of aluminum trichloride was added in batches and reacted overnight. The reaction was quenched by the addition of a saturated aqueous solution of ammonium chloride, filtered, and the filtrate was concentrated and evaporated. The product was collected in a yield of 53.49g, a yield of 74.3%.
General Description
Cyclopropanemethanol (Cyclopropyl carbinol, CPMO), a cycloalkanemethanol, is an anaesthetic. The coupling reaction of cyclopropanemethanol with alkynes to form substituted allylic alcohols has been reported. The microwave spectrum of CPMO has been recorded. Its rotational constants and dipole moment have been determined.
Cyclopropyl carbinol Preparation Products And Raw materials
Raw materials
Preparation Products
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Supplier | Advantage |
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Advent Dyestuffs And Chemicals Private Limited | 58 |
ALS INDIA LIFE SCIENCES | 58 |
JSK Chemicals | 58 |
DHANVI EXIM SERVICES | 58 |
Shree Ganesh Remedies Limited | 58 |
V & V Pharma Industries | 58 |
RESONANCE LABORATORIES PVT LTD | 58 |
Sai Quest Syn. Ltd | 58 |
ASM Organics | 58 |
Renuka Interchem | 58 |
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