GW0742
![GW0742 Structure](CAS/GIF/317318-84-6.gif)
- CAS No.
- 317318-84-6
- Chemical Name:
- GW0742
- Synonyms
- GW0742;CS-2560;GW 0742X;GW 610742;GWdelta 0742;Sarms Gw0742;GW0742 sarms;GW0742 / GW0742;GW0742(GW610742);GW0742 USP/EP/BP
- CBNumber:
- CB4138491
- Molecular Formula:
- C21H17F4NO3S2
- Molecular Weight:
- 471.49
- MOL File:
- 317318-84-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/5 17:10:12
Melting point | 134.5-135.5 °C |
---|---|
Boiling point | 591.5±60.0 °C(Predicted) |
Density | 1.46±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO: >5 mg/mL |
form | solid |
pka | 3.17±0.10(Predicted) |
color | white |
InChI | InChI=1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28) |
InChIKey | HWVNEWGKWRGSRK-UHFFFAOYSA-N |
SMILES | C(O)(=O)COC1=CC=C(SCC2SC(C3=CC=C(C(F)(F)F)C(F)=C3)=NC=2C)C=C1C |
GW0742 price More Price(2)
GW0742 Chemical Properties,Uses,Production
Description
GW0742 is a PPARδ/β agonist very similar in molecular structure to GW501516 (Cardarine) — with the exception of one atom. It is often mentioned in comparison with Cardarine. This drug is mostly used by athletes to improve their stamina. The fat affecting properties of GW0742 also make it a good promoter of energy in the body. Additionally, this drug helps increase the oxidative abilities of your body muscles.
Chemical Properties
Light Yellow Solid
Uses
GW0742 is a small molecule agonist of the human Peroxisome Proliferator-Activated Recept δ (PPAR δ). It shows an EC50 of 1.1 nM against PPAR δ with 100-fold selectivity over the other human subtypes.
Biological Activity
GW 0742 is a potent and highly selective PPARδ agonist. EC50 values are 0.001, 1.1 and 2 μM for transactivation of human PPARδ, -α, and -γ receptors respectively. Neuroprotective in rat cerebellar granule neuronal cultures after brief (12-hour) exposure but exhibits inherent toxicity after prolonged (48-hour) incubation. Increases rate of fatty acid oxidation and protects against ischemia/reperfusion injury in neonatal and adult cardiomyocytes.
GW0742 Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 | China | 891 | 58 | Inquiry |
Wuhan Cell Pharmaceutical Co., Ltd | +86-13129979210 +86-13129979210 | China | 376 | 58 | Inquiry |
Zhuzhou New Peptides Tech Co.,Ltd. | +86-18073326374 +86-18073326374 | China | 145 | 58 | Inquiry |
Guangdong Tuoyuan Biotechnology Co., LTD | +85267545345 | China | 152 | 58 | Inquiry |
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 | China | 3146 | 58 | Inquiry |
Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | China | 436 | 58 | Inquiry |
Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | China | 1090 | 58 | Inquiry |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | China | 616 | 58 | Inquiry |