m-Toluic acid
- CAS No.
- 99-04-7
- Chemical Name:
- m-Toluic acid
- Synonyms
- m-toluic;m-toluicaci;META-TOLUATE;m-Tlouicacid;3-TOLUIC ACID;M-TOLUIC ACID;M-TOLUYLIC ACID;3-Methylbenzoic;meta-toluicacid;M-ToluicAcid>98%
- CBNumber:
- CB4148782
- Molecular Formula:
- C8H8O2
- Molecular Weight:
- 136.15
- MOL File:
- 99-04-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/8/29 17:14:30
| Melting point | 107-113 °C (lit.) |
|---|---|
| Boiling point | 263 °C (lit.) |
| Density | 1.054 g/mL at 25 °C (lit.) |
| vapor pressure | 0.019Pa at 25℃ |
| refractive index | 1.509 |
| Flash point | 150 °C |
| storage temp. | Store below +30°C. |
| solubility | Soluble in alcohol and ether. |
| pka | 4.27(at 25℃) |
| form | Crystalline Solid |
| color | Slightly yellow to beige-yellow |
| PH | 3.69(1 mM solution);3.15(10 mM solution);2.64(100 mM solution); |
| Water Solubility | <0.1 g/100 mL at 19 ºC |
| Merck | 14,9535 |
| BRN | 970526 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| InChIKey | GPSDUZXPYCFOSQ-UHFFFAOYSA-N |
| LogP | 2.37 |
| CAS DataBase Reference | 99-04-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzoic acid, 3-methyl-(99-04-7) |
| EPA Substance Registry System | m-Toluic acid (99-04-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 22-24/25-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XU1200000 | |||||||||
| Autoignition Temperature | 500 °C | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29163900 | |||||||||
| Toxicity | LD50 orally in Rabbit: 7000 mg/kg | |||||||||
| NFPA 704 |
|
m-Toluic acid price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T36609 | m-Toluic acid ReagentPlus?, 99% | 99-04-7 | 100G | ₹1656.23 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T36609 | m-Toluic acid ReagentPlus?, 99% | 99-04-7 | 5G | ₹2067.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T36609 | m-Toluic acid ReagentPlus?, 99% | 99-04-7 | 500G | ₹2814.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.21902 | 3-Methylbenzoic acid for synthesis | 99-04-7 | 250G | ₹3190 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.21902 | 3-Methylbenzoic acid for synthesis | 99-04-7 | 1KG | ₹6090 | 2022-06-14 | Buy |
m-Toluic acid Chemical Properties,Uses,Production
Description
m-toluic acid (MTA) , also known as 3-Methylbenzoic acid or m-Toluate, is a benzoic acid derivative having a floral honey odour. Benzoic acids are organic Compounds containing a benzene ring which bears at least one carboxyl group. Benzoic acid occurs naturally in many plants and its name was also derived from a plant source i.e. Gum benzoin. Although it is used as precursor to plasticizers, preservatives such as sodium benzoate, it also has wide application in many pharmaceutical preparations meant for treatment of fungal skin diseases, topical antiseptics, expectorants, analgesics and decongestants. The benzoic acid derivatives are also very useful due to their bacteriostatic and fragrant properties.
MTA is used as intermediate in various chemical reactions, MTA is used as a chemical intermediate in manufacturing of insect repellent and plastic stabilizer in the chemical industry. It is also used in the production of various chemicals like 3-carboxybenzaldehyde, 3-benzoylphenylacetic acid, 3-methylbenzophenone, and N,N-diethyl- 3-methylbenzamide etc.. It is a main component of N,N-diethylm-toluamide, commonly known as DEET, which is first insect repellent that can be applied to skin or clothing and provide protection against mosquitoes and other biting insects.
Chemical Properties
White to yellowish crystals. Ionization constant 5.3 × 10?5. Slightly soluble in water; soluble in alcohol and ether. Combustible.
Uses
m-Toluic acid is used as a reagent in the preparation of hybrid molecules containing oxadiazole and thiadiazole bearing Schiff base moiety as it has antitumor activities.
Definition
ChEBI: M-toluic acid is a methylbenzoic acid carrying a methyl substituent at position 3. It has a role as a human xenobiotic metabolite. It is a conjugate acid of a m-toluate.
General Description
White to yellowish crystals or mostly yellow flaky solid (with some white flakes). Has a floral-honey odor.
Air & Water Reactions
Fine dust dispensed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard. . Insoluble in water.
Fire Hazard
Flash point data for m-Toluic acid are not available; however, m-Toluic acid is probably combustible.
Purification Methods
Crystallise the acid from water. [Beilstein 9 IV 1712.] Aromatic acid impurities (to <0.05%) can be removed via the (±)--methylbenzylamine salt as described for 2,4-dichlorobenzoic acid [Ley & Yates Organic Process Research & Development 12 120 2008]. The S-benzylisothiuronium salt has m 140o (from aqueous EtOH).
m-Toluic acid Preparation Products And Raw materials
Raw materials
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| KAIVAL CHEMICALS Pvt ltd | +91-8160398972 +91-8160398972 | Gujarat, India | 50 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Ujwal Pharma Pvt Ltd | +91-2228446811 +91-9819482003 | Maharashtra, India | 13 | 58 | Inquiry |
| Dr Prem's Molecules Pvt. Ltd. | +91 9825310038 | New Delhi, India | 547 | 50 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| KAIVAL CHEMICALS Pvt ltd | 58 |
| JSK Chemicals | 58 |
| Ujwal Pharma Pvt Ltd | 58 |
| Dr Prem's Molecules Pvt. Ltd. | 50 |
| CHEMSWORTH | 30 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |