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CHAETOMIN

CHAETOMIN Structure
CAS No.
1403-36-7
Chemical Name:
CHAETOMIN
Synonyms
CTM;CS-1;HSF4;SSFA2;CHETOMIN;CHAETOMIN;NSC 289491;CHETOMIN(RG);DKFZp313O1039;Chetomin,Chaetomin
CBNumber:
CB4173948
Molecular Formula:
C31H30N6O6S4
Molecular Weight:
710.87
MOL File:
1403-36-7.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

CHAETOMIN Properties

Melting point 218-220℃ (chloroform )
Density 1.78±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: soluble
form Off-white to fawn solid.
pka 12.69±0.10(Predicted)
color Off-white to fawn

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
Toxicity rat,LD50,oral,75mg/kg (75mg/kg),"CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(1), Pg. 174, 1980.
NFPA 704
0
2 0

CHAETOMIN price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C9623 Chetomin from Chaetomium cochliodes, ≥98% (HPLC) 1403-36-7 1MG ₹25503.7 2022-06-14 Buy
Sigma-Aldrich(India) SAB1403947 Monoclonal Anti-HSF4 antibody produced in mouse clone 3G3, purified immunoglobulin, buffered aqueous solution 1403-36-7 100μG ₹50671.5 2022-06-14 Buy
Sigma-Aldrich(India) C9623 Chetomin from Chaetomium cochliodes, ≥98% (HPLC) 1403-36-7 5MG ₹76695.13 2022-06-14 Buy
Product number Packaging Price Buy
C9623 1MG ₹25503.7 Buy
SAB1403947 100μG ₹50671.5 Buy
C9623 5MG ₹76695.13 Buy

CHAETOMIN Chemical Properties,Uses,Production

Definition

ChEBI: An organic heteropentacyclic compound of the class of epipolythiodioxopiperazine. Isolated from Chaetomium globosum and Farrowia seminuda, it exhibits immunosuppressive activity.

Biochem/physiol Actions

Chetomin is a natural metabolite produced by several species of the genus Chaetomium. Chetomin is an epidithiodioxopiperazine known to disrupt the hypoxia-inducible factor (HIF) pathway. Chetomin blocks the interaction of HIF1α and HIF2α with transcriptional co-activators p300 and cAMP response element binding (CREB) binding protein (CBP), thereby attenuating hypoxia-inducible transcription. Disrupting the ability of tumors to adapt to hypoxia leads to decreased tumor growth and can serve as an antitumor stratagy. Chetomin also suppresses the proliferation of LPS-induced mouse spleen lymphocytes.

CHAETOMIN Preparation Products And Raw materials

Raw materials

Preparation Products

CHAETOMIN Suppliers

Global( 94)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9155 58 Inquiry
InvivoChem 13549236410 China 6749 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Nanjing Anyan Biological Technology Co., Ltd. 025-52151215 13915956535 13915956535 China 9733 58 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9708 58 Inquiry
Beijing Boorsen Biotechnology Co., Ltd 400-901-9800 18611424007 China 9518 58 Inquiry
Supplier Advantage
BOC Sciences 58
InvivoChem 58
TargetMol Chemicals Inc. 58
Aladdin Scientific 58
RD International Technology Co., Limited 58
InvivoChem 58
Cayman Chemical Company 81
Nanjing Anyan Biological Technology Co., Ltd. 58
Shanghai EFE Biological Technology Co., Ltd. 58
Beijing Boorsen Biotechnology Co., Ltd 58

1403-36-7(CHAETOMIN)Related Search:

Chrysin QUINOMYCIN A Anifostine trihydrate BISPHENOL A DIMETHYL ETHER (3S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE
(3R)-(+)-3-(ETHYLAMINO)PYRROLIDINE [2-(4-METHYLPIPERAZINYL)-1-PHENYLETHYL]METHYLAMINE 1H-Indol-2-amine 1-Piperazineethanamine,-alpha-,-alpha-,4-trimethyl-(9CI) HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE
CHAETOMIN BENZENEMETHANAMINE, 2-AMINO-ALPHA,ALPHA-DIMETHYL CHEMBRDG-BB 4012298 2-(3-PHENYL-PYRROLIDIN-1-YL)-ETHYLAMINE CYCLO(-D-ALA-D-ALA)
2-(4-METHYLPIPERAZINYL)-1-PHENYLETHYLAMINE (S)-2-HYDROXYMETHYL-PIPERAZINE 1,2-BIS(DIMETHYLAMINO)-2-METHYLPROPANE
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Monoclonal Anti-HSF4 antibody produced in mouse DKFZp313O1039 SSFA2 ANTI-HSF4 antibody produced in mouse HSF4 CTM CS-1 CHETOMIN CHAETOMIN Chetomin,Chaetomin Chetomin,Chaetomiumspecies CHETOMIN(RG) NSC 289491 Stereoisomer of 2,3,5a,6,10b,11-hexahydro-3-(hydroxymethyl)-10b-[3-[[4-(hydroxymethyl)-5,7-dimethyl-6,8-dioxo-2,3-dithia-5,7-diazabicyclo[2.2.2]oct-1-yl]methyl]-1H-indol-1-yl]-2-methyl-3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione (3S,5aR,10bS,11aS)-2,3,5a,6,10b,11-hexahydro-3-(hydroxymethyl)-10b-(3-[(1S,4S)-3-[[4-(hydroxymethyl)-5,7-dimethyl-6,8-dioxo-2,3-dithia-5,7-diazabicyclo[2.2.2]oct-1-yl)methyl]-1H-indol-1-yl]-2-methyl-3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione Chetomin (NSC 289491) 3,11a-Epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione, 2,3,5a,6,10b,11-hexahydro-3-(hydroxymethyl)-10b-[(1S,4S)-3-[[4-(hydroxymethyl)-5,7-dimethyl-6,8-dioxo-2,3-dithia-5,7-diazabicyclo[2.2.2]oct-1-yl]methyl]-1H-indol-1-yl]-2-methyl-, (3S,5aR,10bS,11aS)- NSC289491， BRN0077366 Rabbit Anti-HSF4 antibody 1403-36-7 C31H30N6O6S4