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Anifostine trihydrate

Anifostine trihydrate Structure
CAS No.
112901-68-5
Chemical Name:
Anifostine trihydrate
Synonyms
Amifostine;AMIFOSTIN;S-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate;WR2721;ANIFOSTINE;Ethyol trihydrate;Amifostine (150 mg);Amifostine (1019406);Anifostine trihydrate;Amphotericin trihydrate
CBNumber:
CB4316378
Molecular Formula:
C5H17N2O4PS
Molecular Weight:
232.23
MOL File:
112901-68-5.mol
Modify Date:
2024/7/2 8:55:08

Anifostine trihydrate Properties

storage temp. 2-8°C
solubility PBS (pH 7.2): 5 mg/ml
form powder
pka pKa1 <2.0; pKa2 4.2; pKa3 9.0; pKa4 11.7(at 25℃)
color White to off-white
InChIKey JKOQGQFVAUAYPM-UHFFFAOYSA-N
CAS DataBase Reference 112901-68-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22
Safety Statements  26-36
WGK Germany  3
RTECS  TE6491000
HS Code  2930909165
NFPA 704
0
2 0

Anifostine trihydrate price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR2940 Amifostine pharmaceutical secondary standard, certified reference material 112901-68-5 300MG ₹25817.63 2022-06-14 Buy
Sigma-Aldrich(India) A5922 Amifostine trihydrate ≥97% (TLC), powder 112901-68-5 100MG ₹58920.48 2022-06-14 Buy
Product number Packaging Price Buy
PHR2940 300MG ₹25817.63 Buy
A5922 100MG ₹58920.48 Buy

Anifostine trihydrate Chemical Properties,Uses,Production

Uses

Protectant (topical); radioprotector.

brand name

Ethyol (MedImmune) [USAN previously used: Ethiofos.].

Biochem/physiol Actions

Radioprotective agent. Selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy. Selectivity is due to preferential uptake by normal tissues and subsequent metabolic activation to 2-(3-aminopropyl)aminoethanethiol.

Anifostine trihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 262)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
HELPLINE PHARMACY PRIVATE LIMITED 08068979896Ext 462 Delhi, India 1 58 Inquiry
Ocean Blue Pharmaceuticals 08048372931Ext 608 Vadodara, India 1 58 Inquiry
Unitrade Agencies 08048372548Ext 632 Mumbai, India 197 58 Inquiry
Atlanta Associates 08048372939Ext 940 Mumbai, India 184 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Manus Aktteva Biopharma LLP 08048250218Ext 800 Ahmedabad, India 655 58 Inquiry
Sai Quest Syn. Ltd 91-40-23607444 Hyderabad, India 268 58 Inquiry
Opulent Pharma 08068441147Ext 981 Gujarat, India 810 58 Inquiry
Manus Aktteva +91 (79) 6512-3395 New Delhi, India 581 34 Inquiry
OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6211 58 Inquiry

Anifostine trihydrate Spectrum

Amifostine (150 mg) Anifostine trihydrate Ethanethiol,2-[(3-aMinopropyl)aMino]-, 1-(dihydrogen phosphate), hydrate (1:3) Amifostine trihydrate, >=98% Aminopropylamino)ethylsulfanylphosphonic acid trihydrate S-2-(3-AMINOPROPYLAMINO)ETHYL O,O-DIHYDROGEN PHOSPHOROTHIOATE WR2721 Amifostinetrihydrateormonohydrate Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate Amifostine Disulfide (25 mg) 2-(3-aminopropylamino)ethylsulfanylphosphonic acid trihydrate AMINOPROPYL AMINOETHYLTHIOPHOSPHATE Ethyol trihydrate Aminopropylamino)ethylsulfanylphosphonic acid trihydrate USP/EP/BP ANIFOSTINE 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate USP/EP/BP Amifostine trihydrate (WR2721) Amifostine (1019406) Amifostine Disulfide (1019417) Amifostine AMIFOSTIN S-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate DNA-damage,thiol,HIF-PH,cytoprotective,Broad-spectrum,Hypoxia-inducible factors,HIF-α1,WR-2721,MDM-2/p53,Inhibitor,p53,Amifostine trihydrate,WR 2721,inhibit,antiangiogenic,radioprotector,HIF/HIF Prolyl-Hydroxylase,HIFs 2-(3-Amino-propylamino)ethylthiophosphonic acid,trihydrate Amphotericin trihydrate S-(2-((3-aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate hydrate 112901-68-5 1129-68-5 C5H15N2O3PS3H2O C5H21N2O6PS Cancer Research Antitumor Agents BioChemical Therapy Adjuncts Inhibitors 112901-68-5