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Tropisetron

Tropisetron Structure
CAS No.
89565-68-4
Chemical Name:
Tropisetron
Synonyms
CS-348;icf205-930;TROPICACID;TROPISETRON;β-Tropisetron;SS-TROPISETRON;BETA-TROPISETRON;Tropisetron USP/EP/BP;Tropisetron (ICS 205930);TROPISHTRON HYDROCHLORIDE
CBNumber:
CB3236404
Molecular Formula:
C17H20N2O2
Molecular Weight:
284.35
MOL File:
89565-68-4.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

Tropisetron Properties

Melting point 201-202 °C
Boiling point 448.5±35.0 °C(Predicted)
Density 1.26
storage temp. Inert atmosphere,2-8°C
solubility H2O: soluble
form solid
pka 15.38±0.30(Predicted)
color white
CAS DataBase Reference 89565-68-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3

Tropisetron Chemical Properties,Uses,Production

Description

Tropisetron is the third selective 5HT3-antagonist, after ondansetron and granisetron, to be introduced for the management of nausea and vomiting induced by cancer chemotherapy. Similar to the other two 5HT3-antagonists, vopisetron is superior to metoclopramide. The compound has also been reported to have antiarrhythmic activity.

Uses

A substance that is used to prevent nausea and vomiting caused by chemotherapy.

Definition

ChEBI: An indolyl carboxylate ester obtained by formal condensation of the carboxy group of indole-3-carboxylic acid with the hydroxy group of tropine.

Hazard

Human systemic effects.

Tropisetron Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 154)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21667 55 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29825 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-87569265 +86-18612256290 China 2132 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 8744 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Wuhan Fortuna Chemical Co., Ltd +86-027-59207850 China 5989 58 Inquiry
Baoji Guokang Bio-Technology Co., Ltd. 0917-3909592 13892490616 China 9317 58 Inquiry
Sinoway Industrial co., ltd. 0592-5800732; +8613806035118 China 988 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
TROPISETRON 1H-Indole-3-carboxylic acid (1β,5β)-8-methyl-8-azabicyclo[3.2.1]octan-3α-yl ester 1H-Indole-3-carboxylic acid, endo-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester Tropisetron (ICS 205930) 8-methyl-8-azabicyclo(3.2.1)oct-3-ylester,endo-1h-indole-3-carboxylicaci icf205-930 3-TROPANYL-INDOLE-3-CARBOXYLATE HYDROCHL ORIDE(ICS-205,930, NOVOBAN 3-TROPANYL-INDOLE-3-CARBOXYLATE METHIODI DE ICS-205,930, METHIODI TROPISHTRON HYDROCHLORIDE SS-TROPISETRON 1H-INDOLE-3-CARBOXYLIC ACID, (3-ENDO)-8-METHYL-8-AZABICYCLO [3,2,1]OCT-3-YL ESTER 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo-1h-indole-3-carboxylic acid BETA-TROPISETRON TROPICACID Indole-3-carbonyl chloride lαH,5Αh-Tropan-3α-yl indole-3-carboxylate 3-Tropanylindole-3-carboxylate rel-(1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate Tropisetron USP/EP/BP β-Tropisetron CS-348 3H-indole-3-carboxylic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester hydrochloride 8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate hydrochloride NOVABAN; ICS 205930; SDZ-ICS 930 89565-68-4 39565-68-4 C17H2N2O2 C17H6N2O2