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CHAETOMIN

CHAETOMIN Structure
  • ₹25503.7 - ₹76695.13
  • Product name: CHAETOMIN
  • CAS: 1403-36-7
  • MF: C31H30N6O6S4
  • MW: 710.87
  • EINECS:
  • MDL Number:MFCD28137713
  • Synonyms:Monoclonal Anti-HSF4 antibody produced in mouse;DKFZp313O1039;SSFA2;ANTI-HSF4 antibody produced in mouse;HSF4;CTM;CS-1;CHETOMIN
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • 100μG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSAB1403947
  • Product descriptionMonoclonal Anti-HSF4 antibody produced in mouse clone 3G3, purified immunoglobulin, buffered aqueous solution
  • Packaging100μG
  • Price₹50671.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC9623
  • Product descriptionChetomin from Chaetomium cochliodes, ≥98% (HPLC)
  • Packaging5MG
  • Price₹76695.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC9623
  • Product descriptionChetomin from Chaetomium cochliodes, ≥98% (HPLC)
  • Packaging1MG
  • Price₹25503.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SAB1403947 Monoclonal Anti-HSF4 antibody produced in mouse clone 3G3, purified immunoglobulin, buffered aqueous solution 100μG ₹50671.5 2022-06-14 Buy
Sigma-Aldrich(India) C9623 Chetomin from Chaetomium cochliodes, ≥98% (HPLC) 5MG ₹76695.13 2022-06-14 Buy
Sigma-Aldrich(India) C9623 Chetomin from Chaetomium cochliodes, ≥98% (HPLC) 1MG ₹25503.7 2022-06-14 Buy

Properties

Melting point :218-220℃ (chloroform )
Density :1.78±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble
form :Off-white to fawn solid.
pka :12.69±0.10(Predicted)
color :Off-white to fawn

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Chetomin is a natural product isolated from Chaetomium species which has antibacterial and antifungal properties. It is a small molecule inhibitor of hypoxia-inducible factor (HIF) signaling, disrupting the binding of HIF-1α and HIF-2α to p300 at low nanomolar concentrations. Chetomin effectively attenuates the HIF pathway both in cells and in vivo, in mice. It inhibits HIF-dependant signaling, cell growth, and tumor growth in cancer cells and xenografts.

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