ChemicalBook > Product Catalog >API >Circulatory system drugs >Anti-Congestive Heart Failure drugs >CONVALLATOXIN
CONVALLATOXIN
- CAS No.
- 508-75-8
- Chemical Name:
- CONVALLATOXIN
- Synonyms
- Convapur;orglycon;CORGLYKON;Convalpur;corglycon;korglykon;NSC 407808;corglycone;Convallopan;convallaton
- CBNumber:
- CB4190741
- Molecular Formula:
- C29H42O10
- Molecular Weight:
- 550.64
- MOL File:
- 508-75-8.mol
- Modify Date:
- 2023/8/25 11:46:16
Melting point | 238-239℃ (water ) |
---|---|
alpha | D22 -1.7 ± 3° (c = 0.65 in methanol); D25 -9.4 ± 3° (c = 0.72 in dioxane) |
Boiling point | 542°C (rough estimate) |
Density | 1.41±0.1 g/cm3 (20 ºC 760 Torr) |
refractive index | 1.5376 (estimate) |
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
pka | 13.04±0.70(Predicted) |
form | Solid |
color | White to Off-White |
Merck | 13,2538 |
Stability | Hygroscopic |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
---|---|
Signal word | Danger |
Hazard statements | H301+H311+H331 |
Precautionary statements | P261-P264-P280-P301+P310-P302+P352+P312-P304+P340+P311 |
RIDADR | 3249 |
WGK Germany | 2 |
RTECS | GL4025000 |
HazardClass | 6.1(b) |
PackingGroup | III |
Toxicity | LD50 in mice, rats (mg/kg): 10.0 i.p., 16.0 i.v. (Frster) |
CONVALLATOXIN Chemical Properties,Uses,Production
Definition
ChEBI: A cardenolide glycoside that consists of strophanthidin having a 6-deoxy-alpha-L-mannopyranosyl (L-rhamnosyl) group attached at position 3.
Purification Methods
Crystallise convallatoxin from EtOAc, CHCl3/EtOH (9:1) or MeOH/Et2O. The tetraacetate has m 238-242o (from MeOH/Et2O), [] D 25 -5o (CHCl3). [Reyle et al. Helv Chim Acta 33 1541 1950, Fieser & Jacobson J Am Chem Soc 59 2335 1937 Beilstein 1 8 III/IV 3142.]
CONVALLATOXIN Preparation Products And Raw materials
Global( 90)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | China | 1000 | 58 | Inquiry |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3772 | 58 | Inquiry |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | China | 5873 | 58 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30250 | 58 | Inquiry |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | China | 7726 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20290 | 58 | Inquiry |
508-75-8(CONVALLATOXIN)Related Search:
STROPHANTHIN 3ALPHA-1-RHAMNOSIDE
STROPHANTHIDIN ALPHA-L-RHAMNOPYRANOSIDE
STROPHANTHIDIN A-L-RHAMNOPYRANOSIDE
CORGLYKON
CONVALLATOXIN
20(22),5BETA-CARDENOLID-19-AL-3BETA,5BETA,14BETA-TRIOL-3BETA-D-[A-1-RHAMNOPYRANOSIDE]
Convallatoxine
Strophanthidin α-L-rhamnopyranoside, 3β,5α,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide 3-(6-deoxy-α-L-mannopyranoside)
3β-(α-L-Rhamnopyranosyloxy)-5,14-dihydroxy-19-oxo-5β,14β-carda-20(22)-enolide
3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-5β,14β-card-20(22)-enolide
3β5α14-Trihydroxy-19-oxo-5β20(22)-cardenolide 3-(6-deoxy-α-L-mannopyranoside)
Strophanthidin α-L-rhamnopyranoside
CONVALLATOXIN(P)
Convallopan
Convapur
NSC 407808
orglycon
5BETA,20[22]-CARDENOLIDE-19-ONE-3BETA,5ALPHA,14-TRIOL-3-[6-DEOXY-ALPHA-L-MANNOPYRANOSYL]
3BETA,5ALPHA,14-TRIHYDROXY-19-OXO-5BETA,20[22]-CARDENOLIDE-3-[6-DEOXY-ALPHA-L-MANNOPYRANOSYL]
(3beta,5beta)-oxo
0(22)-enolide
3-((6-deoxy-alpha-l-mannopyranosyl)oxy)-5,14-dihydroxy-19-card-20(22)-enolid
3beta-[(6-deoxy-alpha-l-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-5beta-card-2
6-deoxy-strophanthidin-alpha-l-mannopyranosid
convallaotoxin
convallaton
convallatoxoside
convallotoxin
Convalpur
corglycon
corglycone
korglykon
strophanthidin,3-(6-deoxy-alpha-l-mannopyranoside)
strophanthidin-3,alpha-l-rhamnosid
strophanthidinalpha-l-rhamnoside
Convallatoxin (=Corglycon)
CONVALLATOXIN(RG)
CONVALLATOXIN USP/EP/BP
Card-20(22)-enolide, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3β,5β)-
(5S,10S,13R,14S)-5,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-3-[(3,4,5-trihydroxy-6-methyl-2-oxanyl)oxy]-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carboxaldehyde
psoriasis,Nuclear factor-κB,P-gp,Inhibitor,anti-proliferative,colitic,anti-inflammatory,Nuclear factor-kappaB,P-glycoprotein,Peroxisome proliferator-activated receptors,CD243,inhibit,Multidrug resistance protein 1,PPAR,NF-κB,MDR1,Convallatoxin,Pgp,ABCB1,Cluster of differentiation 243,inflammation,substrate
508-75-8
C29H42O10
C21H34N6O7S
Aldehydes
Building Blocks
C13-C60
Carbonyl Compounds
Chemical Synthesis
Organic Building Blocks