17-Methyltestosterone
- CAS No.
- 58-18-4
- Chemical Name:
- 17-Methyltestosterone
- Synonyms
- METHYLTESTOSTERONE;Androsten;17α-Methyltestosterone;Delatestryl;MESTERONE;METANDREN;Nu-man;ru24400;Syndren;Testora
- CBNumber:
- CB4213510
- Molecular Formula:
- C20H30O2
- Molecular Weight:
- 302.46
- MOL File:
- 58-18-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/16 17:35:26
| Melting point | 162-168 °C(lit.) |
|---|---|
| alpha | 79 º (c=1, alcohol) |
| Boiling point | 383.47°C (rough estimate) |
| Density | 1.0434 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| Flash point | 5 °C |
| storage temp. | 2-8°C |
| solubility | H2O: ≤0.5 mg/mL |
| form | solid (photosensitive) |
| pka | 15.13±0.60(Predicted) |
| color | white |
| Water Solubility | 33.88mg/L(25 ºC) |
| Merck | 13,6148 |
| BRN | 2057425 |
| InChIKey | GCKMFJBGXUYNAG-HLXURNFRSA-N |
| CAS DataBase Reference | 58-18-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 17(Alpha)-methyl-delta4-androsten-17-(beta)-ol-3-one(58-18-4) |
| EPA Substance Registry System | Methyltestosterone (58-18-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H350-H361fd | |||||||||
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 | |||||||||
| Hazard Codes | T,Xn,F,Xi | |||||||||
| Risk Statements | 45-63-22-20-19-11-61-60-36/37/38-38-10 | |||||||||
| Safety Statements | 53-36/37-45-24/25-22 | |||||||||
| RIDADR | 3249 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | BV8400000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29372900 | |||||||||
| Toxicity | man,TDLo,oral,39mg/kg/33W-I (39mg/kg),LIVER: "JAUNDICE, CHOLESTATIC",American Journal of Gastroenterology. Vol. 82, Pg. 461, 1987. | |||||||||
| NFPA 704 |
|
17-Methyltestosterone price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | M-906 | 17α-Methyltestosterone solution 1.0?mg/mL in 1,2-dimethoxyethane, ampule of 1?mL, certified reference material, Cerilliant? | 58-18-4 | 1ML | ₹11943.4 | 2022-06-14 | Buy |
| ottokemi | M 2232 | Methyl testosterone 97% | 58-18-4 | 1gm | ₹1881 | 2022-05-26 | Buy |
| ottokemi | M 2232 | Methyl testosterone 97% | 58-18-4 | 5gm | ₹5292 | 2022-05-26 | Buy |
17-Methyltestosterone Chemical Properties,Uses,Production
Description
Methyltestosterone is a synthetic analog of testosterone that possesses all of the properties of testosterone, exhibiting stimulatory action on the development of male sex organs and secondary sex characteristics, although it is not degraded by enzymes in the gastrointestinal tract, and therefore it can only be taken orally
Chemical Properties
white to slightly yellowish-white crystalline
Uses
Androgen. It has been used as an androgenic agent. Controlled substance (anabolic steroid).
Definition
ChEBI: A 17beta-hydroxy steroid that is testosterone bearing a methyl group at the 17alpha position.
Pharmacokinetics
The synthesis of 17α-methyltestosterone made available a compound that was orally active in daily doses between 10 and 50 mg, which is equivalent to a 400 mg oral dose of testosterone. The presence of a 17α alkyl group reduces susceptibility to hepatic oxidative metabolism, thereby increasing oral bioavailability by slowing metabolism. Following oral administration, methyltestosterone is well absorbed from the gastrointestinal tract, with a half-life of approximately 3 hours. This drug has the androgenic and anabolic activities of testosterone. Although orally active, it is more effective when administered sublingually. The alkylated oral androgens should be viewed as potentially hepatotoxic and should not be used.
Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion. Human teratogenic effects by ingestion: developmental abnormalities of the urogenital system. Experimental teratogenic and reproductive effects. Human systemic effects: cholestatic jaundce, weight loss or decreased weight gain. Questionable human carcinogen producing liver tumors. A synthetic androgenic steroid. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods
This anabolic steroid is crystallised from hexane or hexane/*benzene. It has E1cm 1% 495-530 at 241nm (EtOH). The colour reaction with 2,4-dinitrophenyl hydrazine is used for assaying it. [Gornall & Macdonald J Biol Chem 201 279 1953.] In another colour reaction the sterone (1mg) in acetic acid (0.2ml) + 88% H3PO4 (2mL) is allowed to stand for 1hour when it becames fluorescent. After 1hour it is diluted with acetic acid (~3mL) and provides a strong yellow fluorescence with the intensity of 50-100 times that of estrone. [Stuart & Stuckey J Pharm Pharmacol 1 130 1949, Openauer Rec Trav Chim Pays-Bas 56 137 137, Beilstein 8 IV 1010.]
17-Methyltestosterone Preparation Products And Raw materials
Raw materials
1of2
chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| KARPSCHEM LABORATORIES | +91-7249203006 +91-7249203006 | Maharashtra, India | 786 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| qingdao future trading Co., Ltd | +86-13335044410 +86-13335044410 | China | 110 | 58 | Inquiry |
| .GZ HONESTCHEM CO.,LTD | +86-15013270415 | China | 246 | 58 | Inquiry |
| Guangdong Tuoyuan Biotechnology Co., LTD | +85267545345 | China | 152 | 58 | Inquiry |
| Shandong Hanjiang Chemical Co., Ltd | +86-0533-2066820 +8618369939125 | China | 889 | 58 | Inquiry |
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