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(+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE

CAS No.: 42542-10-9

Chemical Name:: (+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE

Synonyms: Methylenedioxymethamphetamine;XTC;3,4-MDMA;C07577;DL-MDMA;ecstacy;(+/-)-MDMA;AURORA KA-7748;(±)-MDMA solution;3,4-METHYLENDIOXYMETHAMPHETAMIN

CBNumber:: CB4221584

Molecular Formula:: C11H15NO2

Molecular Weight:: 193.25

MOL File:: 42542-10-9.mol

Modify Date:: 2023/5/15 10:43:30

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(+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE Properties

Boiling point	bp0.4 100-110°
Density	1.100±0.06 g/cm3(Predicted)
Flash point	9℃
storage temp.	2-8°C
pka	10.32±0.10(Predicted)
InChIKey	SHXWCVYOXRDMCX-UHFFFAOYSA-N
EPA Substance Registry System	1,3-Benzodioxole-5-ethanamine, N,.alpha.-dimethyl- (42542-10-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS02,GHS06,GHS08
Signal word	Danger
Hazard statements	H225-H301+H311+H331-H370
Precautionary statements	P210-P260-P280-P301+P310-P311
Hazard Codes	F,T
Risk Statements	11-23/24/25-39/23/24/25
Safety Statements	7-16-36/37-45
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	1
Toxicity	A novel psychoactive drug chemically related to the hallucinogenic agent MDA, but reported to be non-hallucinogenic. Obtained by direct synthesis, at high doses it is reported to show a stimulant-like effect in animals. Its LD50 is 97 mg/kg, i. p., 49 mg/kg, i.p., 14 mg/kg, i.v., and 22 mg/kg, i.v. in mice, rats, dogs, and monkeys, respectively. At higher doses, MDMA has pressor effects and produces tachycardia, and causes damage to serotonin neurons in both rats and monkeys. The (S)- (1)-enantiomer is more active than the (R)-(?′)-enantiomer and, like amphetamine, the pharmacological effects may be due to a release of endogenous monoamine neurotransmitter, probably serotonin and/or norepinephrine. MDMA is also an inhibitor of monoamine uptake into brain synaptosomes. Symptoms include pronounced mydriasis, with nystagmus and jaw clenching, and nausea also is often reported. This substance produces a feeling of well-being and euphoria and is similar in some respects to MDA, in that it seems to enhance a sense of empathy and emotional openness in users. Toxic reactions would appear to occur as a result of the pressor action, and sympathomimetic effects of the drug. No appropriate therapeutic intervention has been reported. Peripheral adrenergic blocking agents, or chlorpromazine, have been used, however, to prevent death in dogs following a lethal i.v. dose of the chemically related agent MDA.

(+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	M-013	(±)-MDMA solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?	42542-10-9	1ML	₹3311.7	2022-06-14	Buy

Product number	Packaging	Price	Buy
M-013	1ML	₹3311.7	Buy

(+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE Chemical Properties,Uses,Production

Definition

ChEBI: A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.

Metabolic pathway

Four biotransformation pathways of 3,4- (methylenedioxy)methamphetamine (MDMA) in rats are identified as N-demethylation, O-dealkylation, deamination, and conjugation (O-methylation, O- glucuronidation, and/or sulfation). Specific MDMA metabolites identified are 3-hydroxy-4- methoxymethamphetamine, 4-hydroxy-3- methoxymethamphetamine, 3,4- dihydroxymethamphetamine, 4-hydroxy-3- methoxyamphetamine, 3,4- (methylenedioxy)amphetamine (MDA), (4-hydroxy-3- methoxyphenyl)acetone, [3,4- (methylenedioxy)phenyl]acetone, and (3,4- dihydroxyphenyl)acetone. MDMA is metabolized by 10 000 g rat liver supernatant to 4-hydroxy-3- methoxymethamphetamine, 3,4- dihydroxymethamphetamine, MDA, and [3,4- (methylenedioxy)phenyl]acetone. Also, the 10 000 g rat brain supernatant metabolizes MDMA to 4-hydroxy- 3-methoxymethamphetamine, 3,4- dihydroxymethamphetamine, 4-hydroxy-3- methoxyamphetamine, and MDA.

(+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE

42542-10-9((+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE)Related Search:

(-)-STYLOPINE CEPHALOTAXINE Lycorine hydrochloride RHOEADINE N-Methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine

HARRINGTONINE (+)-Bicuculline CHELIDONINE (-)-BICUCULLINE METHOBROMIDE (-)-BICUCULLINE METHIODIDE

S(+)-3 4-MDMA HCL (-)-BICUCULLINE METHOCHLORIDE ECSTASY HYDROCHLORIDE CALIFORNIDINE PERCHLORATE ESCHSCHOLTZINE HCL

ESCHOLZINE (-)-MDO-NPA HYDROCHLORIDE OXYCHELIDONINE Methylenedioxymethamphetamine

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(+/-)-MDMA DL-MDMA AURORA KA-7748 (+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE 3,4-MDMA (±)-MDMA [(±)-3,4-Methylenedioxymethamphetamine] (+/-)-3,4-MethylenedioxyMethaMphetaMin 1-(1,3-Benzodioxol-5-yl)-N-methyl-2-propanamine 1,3-Benzodioxole-5-ethanamine, N,alpha-dimethyl- 3,4-Methylenedioxymethylamphetamine 3,4-Methylenedioxymethylamphetamine, N-methyl- Methamphetamine, 3,4-methylenedioxy Methylenedioxymethamphetamine Methylenedioxymethamphetamine (MDMA) XTC 1-benzo[1,3]dioxol-5-yl-N-methyl-propan-2-amine hcl. 3,4-METHYLENDIOXYMETHAMPHETAMIN N-Methyl-3,4-methylenedioxyamphetamine 3,4-METHYLENDIOXYMETHAMPHETAMIN, >99% (HPLC) N,1-Dimethyl-2-(1,3-benzodioxole-5-yl)ethanamine N,α-Dimethyl-1,3-benzodioxole-5-ethanamine N-Methyl methyldimethoxymethylamphetamine N-Methyl-1-(1,3-benzodioxole-5-yl)-2-propanamine N-Methyl-α-methyl-3,4-(methylenebisoxy)phenethylamine ecstacy C07577 Methanol (test (±)-MDMA, 1.0 mg/Ml) (±)-MDMA solution 1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine 1,3-Benzodioxole-5-ethanamine, N,α-dimethyl- (+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE 42542-10-9 54949-52-0 42542-10-9 MDMA