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Pizotifen

Pizotifen Structure
CAS No.
15574-96-6
Chemical Name:
Pizotifen
Synonyms
Litec;bc105;BC 105;PIZOTIFEN;Pizotifan;Pizotylene;Pizotyline;Pizotifenum;Sandomigram;Sandomigran
CBNumber:
CB4230373
Molecular Formula:
C19H21NS
Molecular Weight:
295.44
MOL File:
15574-96-6.mol
MSDS File:
SDS
Modify Date:
2023/9/6 17:45:48

Pizotifen Properties

Melting point 140-142°C
Boiling point 436.7±45.0 °C(Predicted)
Density 1.164±0.06 g/cm3(Predicted)
storage temp. room temp
solubility DMSO: ≥8mg/mL
pka pKa 6.95 (Uncertain)
form powder
color White to Off-White
Merck 14,7515
CAS DataBase Reference 15574-96-6(CAS DataBase Reference)
NIST Chemistry Reference Pizotyline(15574-96-6)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H361
Precautionary statements  P201-P301+P312+P330-P308+P313
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22-63
Safety Statements  26-37/39-36/37
WGK Germany  3
RTECS  TM7165000
HS Code  2934.99.3000
NFPA 704
0
2 0

Pizotifen price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) B9688 Pizotifen ≥98% (HPLC) 15574-96-6 10MG ₹9601.78 2022-06-14 Buy
Sigma-Aldrich(India) B9688 Pizotifen ≥98% (HPLC) 15574-96-6 50MG ₹38829.28 2022-06-14 Buy
TCI Chemicals (India) P2344 Pizotifen 15574-96-6 200MG ₹8600 2022-05-26 Buy
Product number Packaging Price Buy
B9688 10MG ₹9601.78 Buy
B9688 50MG ₹38829.28 Buy
P2344 200MG ₹8600 Buy

Pizotifen Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Solid

Uses

Serotonin antagonist structurally related to Cyproheptadine. Antimigraine; appetite stimulant.

Indications

Pizotifen, a potent antihistamine and antiserotonin agent usually prescribed for migraine prophylaxis, has had reported success in patients with polycythemia vera.

Definition

ChEBI: A benzocycloheptathiophene that is 9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene 4-ylidene)-1-methylpiperidine which is joined from the 4 position to the 4 position of an N-methylpiperidine moiety b a double bond. It is a sedating antihistamine, with strong serotonin antagonist and weak antimuscarinic activity. It is generally used as the malate salt for the treatment of migraine and the prevention of headache attacks during cluster periods.

Pizotifen Preparation Products And Raw materials

Global( 203)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Kebee Pharmachemie Pvt., Ltd. 91-22-28328669 Maharashtra, India 65 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
bm chemie 08048250160Ext 924 Mumbai, India 82 58 Inquiry
Hebei Mojin Biotechnology Co., Ltd +86 13288715578 +8613288715578 China 12460 58 Inquiry
Xiamen Wonderful Bio Technology Co., Ltd. +8613043004613 China 305 58 Inquiry

Pizotifen Spectrum

Pizotylene PIZOTHIFENUM Pizotifenum Pizotyline (base and/or unspecified salts) 4-OXO-9,10-DIHYDRO-4H-BENZO(4,5) CYCLOHEPTO(1,2,B) THIOPHENE PIZOTIFEN 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine BC 105 bc105 Litec Piperidine, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methyl- piperidine,4-(9,10-dihydro-4h-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-me Pizotifan Pizotyline Pizotyline maleate Sandomigram Sandomigran Sandomygran Pizotyline-D3 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine Pizotifen USP/EP/BP 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine 15574-96-6 574-96-6 C19H21NS Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds Sandomigran, pizotyline Pizotifen Active Pharmaceutical Ingredients