ANTIBIOTIC UCN-02

ANTIBIOTIC UCN-02 Structure
CAS No.
121569-61-7
Chemical Name:
ANTIBIOTIC UCN-02
Synonyms
UCN-02;UCN02,UCN 02;ANTIBIOTIC UCN-02;9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-, (3S,9S,10R,11R,13R)-
CBNumber:
CB42446750
Molecular Formula:
C28H26N4O4
Molecular Weight:
482.53
MOL File:
121569-61-7.mol
Modify Date:
2024/7/2 8:55:08

ANTIBIOTIC UCN-02 Properties

Boiling point 705.7±60.0 °C(Predicted)
Density 1.63±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form solution in ethanol.
pka 12.25±0.70(Predicted)
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02
Signal word  Danger
NFPA 704
3
0 0

ANTIBIOTIC UCN-02 Chemical Properties,Uses,Production

Description

UCN-02 is a derivative of staurosporine and a stereoisomer of UCN-01 first isolated from a high staurosporine-producing Streptomyces culture as a minor co-metabolite. UCN-02 inhibits protein kinase C with a slightly reduced potency than UCN-01 (IC50 = 62 and 4.1 nM, for UNC-02 and UCN-01, respectively) and is cytotoxic to the growth of HeLa S3 cells.

Uses

UCN-02 is an indolocarbazole isolated from a high staurosporine-producing Streptomyces culture as a minor co-metabolite. Although less selective than its isomer UCN-01, UCN-02 exhibits comparable activity and probably acts by similar mechanisms.

ANTIBIOTIC UCN-02 Preparation Products And Raw materials

Raw materials

Preparation Products

ANTIBIOTIC UCN-02 Suppliers

Global( 41)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
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MedChemExpress 021-58955995 United States 6398 58 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 China 29778 58 Inquiry
Lynnchem 86-(0)29-85992781 17792393971 China 4587 58 Inquiry
UCN-02 ANTIBIOTIC UCN-02 9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-, (3S,9S,10R,11R,13R)- UCN02,UCN 02 121569-61-7