Sucrose octaacetate
- CAS No.
- 126-14-7
- Chemical Name:
- Sucrose octaacetate
- Synonyms
- Soa;FEMA 3038;SUCROSE OCTACETATE;Octa D;aacetate;204-772-1;bitter taste;OCTAACETYLSUCROSE;Sucrose octa actate;Sucrose octaacetate
- CBNumber:
- CB4296191
- Molecular Formula:
- C28H38O19
- Molecular Weight:
- 678.59
- MOL File:
- 126-14-7.mol
- Modify Date:
- 2024/8/15 19:00:21
Melting point | 82-85 °C(lit.) |
---|---|
Boiling point | 260 °C(lit.) |
alpha | D25.4 +58.5° (c = 2.56 in abs alcohol) |
Density | 1.28 |
FEMA | 3038 | SUCROSE OCTAACETATE |
refractive index | 60 ° (C=2, EtOH) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) |
form | Powder |
color | White to creamy white |
Odor | odorless |
Odor Type | odorless |
optical activity | [α]22/D +58.8°, c = 2.5 in ethanol |
Water Solubility | SLIGHTLY SOLUBLE |
Merck | 14,8881 |
BRN | 79290 |
InChIKey | ZIJKGAXBCRWEOL-SAXBRCJISA-N |
LogP | 3.19 |
CAS DataBase Reference | 126-14-7(CAS DataBase Reference) |
NIST Chemistry Reference | Sucrose, octaacetate(126-14-7) |
EPA Substance Registry System | Sucrose octaacetate (126-14-7) |
SAFETY
Risk and Safety Statements
Hazard Codes | Xi |
---|---|
Risk Statements | 36/37/38 |
Safety Statements | 24/25-37/39-26 |
WGK Germany | 2 |
RTECS | WN6620000 |
F | 3 |
HS Code | 29400090 |
Toxicity | LD50 orally in Rabbit: 5000 mg/kg LD50 dermal Rabbit 5000 mg/kg |
Sucrose octaacetate price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | W303801 | Sucrose octaacetate ≥97%, FG | 126-14-7 | 1SAMPLE-K | ₹5141.88 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | W303801 | Sucrose octaacetate ≥97%, FG | 126-14-7 | 1KG | ₹9699.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | W303801 | Sucrose octaacetate ≥97%, FG | 126-14-7 | 10KG | ₹68554.73 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | W303801 | Sucrose octaacetate ≥97%, FG | 126-14-7 | 25KG | ₹129640.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 94474 | D-(+)-Sucrose octaacetate analytical standard | 126-14-7 | 100MG | ₹13791.05 | 2022-06-14 | Buy |
Sucrose octaacetate Chemical Properties,Uses,Production
Chemical Properties
Sucrose octaacetate occurs as white hygroscopic powder. It is practically odorless with a bitter taste.
Uses
Octa-O-acetyl D-(+)-Surcose was used in studies involving human bitter taste receptor hTAS2R46.
Preparation
May be prepared by heating sucrose, acetamide and sodium acetate; or by acetylation of sucrose using acetic anhydride, zinc chloride and acetic acid.
Production Methods
Sucrose octaacetate is typically produced by chemical synthesis; one reported synthetic method is by pyridine-catalyzed acetylation of sucrose.
Pharmaceutical Applications
Sucrose octaacetate is used as an alcohol denaturant in pharmaceutical formulations. It is also used as a bittering agent, and is incorporated into preparations intended to deter nail-biting or thumb-sucking.
Safety Profile
Slightly toxic by ingestion andskin contact. A skin irritant. When heated todecomposition it emits acrid smoke and irritating vapors.
Safety
Sucrose octaacetate is generally regarded as safe. It is considered
slightly hazardous in cases of skin contact (irritant), ingestion, or
inhalation.
LD50 (rabbit, skin): >5 g/kg
LD50 (rat, oral): >5 g/kg
storage
Sucrose octaacetate is a stable material and should be stored in a well-closed, airtight container. Store in a cool, dry place; moisture may cause instability.
Purification Methods
After three recrystallisations from EtOH or 95% EtOH (charcoal), the m of the octaacetate rises to 88-90o, or Et2O with m 89o and [] D +58.5o (c 2.6, EtOH). It has a bitter taste. [Linstead et al. J Am Chem Soc 62 3260 1940, Lemieux & Huber J Am Chem Soc 78 4117 1956, Beilstein 17/8 V 410.]
Regulatory Status
GRAS listed. Approved by the FDA as both a direct and an indirect food additive, and as a nail-biting deterrent for over-the-counter drug products.
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Kiama Research Labs | 08046033202 | Gujarat, India | 26 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Zhejiang Synose Tech Co., Ltd | 579-82270620 | CHINA | 218 | 58 | Inquiry |
Hebei Guanlang Biotechnology Co,.LTD | +86-19930503253; +8619930503252 | China | 5831 | 58 | Inquiry |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | China | 2503 | 58 | Inquiry |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | China | 2989 | 58 | Inquiry |
airuikechemical co., ltd. | +undefined86-15315557071 | China | 983 | 58 | Inquiry |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | China | 3002 | 58 | Inquiry |
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