Halobetasol propionate
- CAS No.
- 66852-54-8
- Chemical Name:
- Halobetasol propionate
- Synonyms
- CGP-14458;BMY-30056;Ultravate;Miracorten;ulobetasol propionate;Uiobetasol Propionate;Halobatasol Proionate;HALOBETASOL PROPIONATE;HalobetasolPropionate>Halobetasol Propionate (200 mg)
- CBNumber:
- CB4305095
- Molecular Formula:
- C25H31ClF2O5
- Molecular Weight:
- 484.96
- MOL File:
- 66852-54-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/1 18:08:31
| Melting point | 213-215°C |
|---|---|
| Boiling point | 570.7±50.0 °C(Predicted) |
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Dioxane (Sparingly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 12.55±0.70(Predicted) |
| color | White to Off-White |
| InChIKey | BDSYKGHYMJNPAB-QNGYMBKVNA-N |
| SMILES | O([C@@]1([C@H](C[C@@]2([H])[C@]3([H])C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C)C(=O)CCl)C(=O)CC |&1:1,2,4,6,9,17,19,21,24,r| |
| CAS DataBase Reference | 66852-54-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H372-H341-H361 | |||||||||
| Precautionary statements | P260-P264-P270-P314-P501-P201-P202-P281-P308+P313-P405-P501-P201-P202-P281-P308+P313-P405-P501 | |||||||||
| HS Code | 2937220000 | |||||||||
| NFPA 704 |
|
Halobetasol propionate price More Price(2)
Halobetasol propionate Chemical Properties,Uses,Production
Description
Halobetasol propionate is a new ultra-potent topical corticosteroid exhibiting both antiinflammatory and antihyperplasia properties. The compound is recommended for the treatment of moderate to severe corticosteroid-responsive dermatoses and appears to be particularly effective in patients with plaque psoriasis. It inhibits dermatitis induced by ultraviolet light in guinea pigs (ED50 = 1.45 μg/animal) and by oxazolone in mice (ED50 = 0.8 μg/animal). Halobetasol propionate also has anti-inflammatory effects on croton oil-induced ear edema in rats (ED50s = 10 μg/ml and 0.5 μg/ear) and mice (ED50s = 1.2 and <0.32 μg/ear after 6 and 24 hours of treatment, respectively). Topical formulations containing halobetasol propionate have been used for inflammatory and pruritic dermatitis.
Chemical Properties
White Solid
Uses
Halobetasol propionate is a corticosteroid (cortisone-like medicine or steroid). As an anti-inflammatory drug, halobetasol topical is used to help relieve redness, itching, swelling, or other discomfort caused by certain skin conditions. It is also used to treat plaque psoriasis.This medicine is available only with doctor's prescription.
Halobetasol propionate Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
| Micro Orgo Chem | +91-91-022-24969510 +91-9082984052 | Mumbai, India | 66 | 58 | Inquiry |
| Gonane Pharma | +91-9819380043 +91-9819380043 | NaviMumbai, India | 192 | 58 | Inquiry |
| Anuh Pharma Ltd (SK GROUP) | +912266227575 | Maharashtra, India | 38 | 58 | Inquiry |
| Horster Biotek Pvt Ltd | +91-7359657360 +91-9898127219 | Gujarat, India | 58 | 58 | Inquiry |
| Stermone Chemicals Pvt Ltd | +91-9328939700 +91-9328939700 | Gujarat, India | 20 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Maharshi Pharma Chem | +91-7940359347 +91-7433927173 | Gujarat, India | 24 | 58 | Inquiry |
| Prachem Laboratories | +91-7948993109 +91-7383072020 | Gujarat, India | 44 | 58 | Inquiry |
| Dy - Mach Pharma | +91-2265018321 +91-2226833227 | Maharashtra, India | 18 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Jigs Chemical ltd | 58 |
| Micro Orgo Chem | 58 |
| Gonane Pharma | 58 |
| Anuh Pharma Ltd (SK GROUP) | 58 |
| Horster Biotek Pvt Ltd | 58 |
| Stermone Chemicals Pvt Ltd | 58 |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | 58 |
| Maharshi Pharma Chem | 58 |
| Prachem Laboratories | 58 |
| Dy - Mach Pharma | 58 |
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