TANNIC ACID
- CAS No.
- 5424-20-4
- Chemical Name:
- TANNIC ACID
- Synonyms
- TANNIN;TANNINUM;FEMA 3042;GERBSAURE;DIGALLIC ACID;CHINESE TANNIN;CHINESE GALLOTANNIN;TANNIC ACID, 25 G+100 ML H2O;PENTA (M-DIGALLOYL) GLUCOSEN F;Gallotannin[Pentadigalloylglucose
- CBNumber:
- CB4305277
- Molecular Formula:
- C76H52O46
- Molecular Weight:
- 1701.21
- MOL File:
- 5424-20-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:08
| Melting point | 218 °C(lit.) |
|---|---|
| Density | 2.12±0.1 g/cm3(Predicted) |
| Flash point | 198 °C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility |
DMSO:10.0(Max Conc. mg/mL);5.88(Max Conc. mM) PBS (pH:7.2):0.3(Max Conc. mg/mL);0.176(Max Conc. mM) |
| form | Solid |
| pka | 6.00±0.50(Predicted) |
| color | Off-white to light brown |
TANNIC ACID Chemical Properties,Uses,Production
Description
Gallotannin is a polyphenol of gallic acid that has been found in various plants and has antioxidant, anti-inflammatory, antiviral, and antiproliferative biological activities. Gallotannin (1 μM) inhibits the intracellular production of reactive oxygen species (ROS) and DNA damage induced by phorbol 12-myristate 13-acetate (TPA; ) in human polymorphonuclear neutrophils (PMNs). It also decreases TPA-induced nitric oxide release by 90% from primary rat hepatocytes when used at a concentration of 0.5 mM. Gallotannin inhibits hepatitis C virus (HCV) entry into Huh7.5 human hepatoma cells (IC50 = 5.8 μM) and inhibits the proliferation of MDA-MB-231 and MCF-7 human breast cancer cells (IC50s = 2.5 and 4 μM, respectively). In a rat model of middle cerebral artery occlusion (MCAO), it increases superoxide dismutase (SOD1) protein levels and decreases the amount of proteins modified by malondialdehyde (MDA) in ischemic brain tissue when administered at a dose of 10 mg/kg.
Definition
Any of several yellow organic compounds found in vegetable sources such as bark of trees, oak galls, and tea. They are used in tanning animal skins to make leather and as mordants in dyeing. Tannic acid (a type of tannin) is a white solid heterocyclic organic acid extracted from oak galls and used for making dyes and inks.
TANNIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26216 | 58 | Inquiry |
| Hebei Duling International Trade Co. LTD | +8617333973358 | China | 15438 | 58 | Inquiry |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33350 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| Hach Company, Inc. | 970-669-3050 | United States | 404 | 81 | Inquiry |
| ABCR GmbH & CO. KG | 49 721 95061 0 | Germany | 6846 | 75 | Inquiry |
| Rhawn Reagent | 400-400-1332688 18019345275 | China | 15503 | 58 | Inquiry |
| Aikon International Limited | 025-66113011 18112977050 | China | 16028 | 58 | Inquiry |
| Bide Pharmatech Ltd. | 400-1647117 15221909166 | China | 41438 | 60 | Inquiry |
| Henan Weitesi Chemical Technology Co. LTD | 0371-0371-55135753 18003832934 | China | 9993 | 58 | Inquiry |
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