CGP 35348
- CAS No.
- 123690-79-9
- Chemical Name:
- CGP 35348
- Synonyms
- CGP 35348;CGP 35348 hydrate;(3-AMINOPROPYL)(DIETHOXYMETHYL)PHOSPHINIC ACID;Phosphinic acid, (3-aminopropyl)(diethoxymethyl)-;P-(3-Aminopropyl)-P-(diethoxymethyl)phosphinic acid;Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)-;(3-Aminopropyl)(diethoxymethyl)phosphinic acid hydrate;spatial learning,neuromuscular,neonatal damage,CGP-35348,brain penetrant,GABA Receptor,CGP35348,Gamma-aminobutyric acid Receptor,centrally,GABAB,CGP 35348,Inhibitor,γ-Aminobutyric acid Receptor,inhibit,active
- CBNumber:
- CB4386728
- Molecular Formula:
- C8H20NO4P
- Molecular Weight:
- 225.22
- MOL File:
- 123690-79-9.mol
- Modify Date:
- 2023/9/4 15:50:00
CGP 35348 price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | C5851 | CGP 35348 hydrate ≥97% (NMR), solid | 123690-79-9 | 5MG | ₹16389.05 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C5851 | CGP 35348 hydrate ≥97% (NMR), solid | 123690-79-9 | 25MG | ₹65285.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 5.05895 | CGP 35348 - CAS 123690-79-9 - Calbiochem | 123690-79-9 | 10MG | ₹16470 | 2022-06-14 | Buy |
CGP 35348 Chemical Properties,Uses,Production
Uses
CGP 35348 hydrate has been used as a γ-aminobutyric acid-B (GABAB) receptor inhibitor:
- to study its effects on intrinsic optical signal (IOS) in rat hippocampus
- alone or in combination with sodium salicylate to study its effects on auditory responses in the rat′s dorsal cortex of rat
- to study its effects on hepatocellular carcinoma cells (HCC)
Biological Activity
Selective, brain penetrant GABA B receptor antagonist (IC 50 = 34 μ M as measured in rat cortical membranes). Has higher affinity for postsynaptic versus presynaptic receptors.
Biochem/physiol Actions
CGP 35348 is a γ-aminobutyric acid-B (GABAB) receptor antagonist. It has a higher affinity towards post-versus presynaptic receptors that can penetrate the blood-brain barrier.
CGP 35348 Preparation Products And Raw materials
Raw materials
Preparation Products
CGP 35348 Suppliers
Global( 39)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | China | 48465 | 58 | Inquiry |
RD International Technology Co., Limited | 18024082417 | China | 9268 | 58 | Inquiry |
Cayman Chemical Company | (800) 364-9897 | United States | 6618 | 81 | Inquiry |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | China | 8736 | 58 | Inquiry |
BOC Sciences | USA | 0 | 65 | Inquiry | |
Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | China | 4659 | 58 | Inquiry |
Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | China | 11710 | 58 | Inquiry |
Tocris Bioscience | +44 (0) 117 916 3333 | United Kingdom | 5729 | 77 | Inquiry |
123690-79-9(CGP 35348)Related Search:
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CGP 35348
(3-AMINOPROPYL)(DIETHOXYMETHYL)PHOSPHINIC ACID
(3-Aminopropyl)(diethoxymethyl)phosphinic acid hydrate
CGP 35348 hydrate
P-(3-Aminopropyl)-P-(diethoxymethyl)phosphinic acid
Phosphinic acid, (3-aminopropyl)(diethoxymethyl)-
spatial learning,neuromuscular,neonatal damage,CGP-35348,brain penetrant,GABA Receptor,CGP35348,Gamma-aminobutyric acid Receptor,centrally,GABAB,CGP 35348,Inhibitor,γ-Aminobutyric acid Receptor,inhibit,active
Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)-
123690-79-9
C8H20NO4P
GABA/Glycine receptor
GABA