CGP 35348

CGP 35348 Structure
CAS No.
123690-79-9
Chemical Name:
CGP 35348
Synonyms
CGP 35348;CGP 35348 hydrate;(3-AMINOPROPYL)(DIETHOXYMETHYL)PHOSPHINIC ACID;Phosphinic acid, (3-aminopropyl)(diethoxymethyl)-;P-(3-Aminopropyl)-P-(diethoxymethyl)phosphinic acid;Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)-;(3-Aminopropyl)(diethoxymethyl)phosphinic acid hydrate;spatial learning,neuromuscular,neonatal damage,CGP-35348,brain penetrant,GABA Receptor,CGP35348,Gamma-aminobutyric acid Receptor,centrally,GABAB,CGP 35348,Inhibitor,γ-Aminobutyric acid Receptor,inhibit,active
CBNumber:
CB4386728
Molecular Formula:
C8H20NO4P
Molecular Weight:
225.22
MOL File:
123690-79-9.mol
Modify Date:
2023/9/4 15:50:00

CGP 35348 Properties

storage temp. −20°C
solubility H2O: >10 mg/mL
form solid
color white
Water Solubility Soluble in water (100mM)

SAFETY

Risk and Safety Statements

WGK Germany  3

CGP 35348 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C5851 CGP 35348 hydrate ≥97% (NMR), solid 123690-79-9 5MG ₹16389.05 2022-06-14 Buy
Sigma-Aldrich(India) C5851 CGP 35348 hydrate ≥97% (NMR), solid 123690-79-9 25MG ₹65285.58 2022-06-14 Buy
Sigma-Aldrich(India) 5.05895 CGP 35348 - CAS 123690-79-9 - Calbiochem 123690-79-9 10MG ₹16470 2022-06-14 Buy
Product number Packaging Price Buy
C5851 5MG ₹16389.05 Buy
C5851 25MG ₹65285.58 Buy
5.05895 10MG ₹16470 Buy

CGP 35348 Chemical Properties,Uses,Production

Uses

CGP 35348 hydrate has been used as a γ-aminobutyric acid-B (GABAB) receptor inhibitor:

  • to study its effects on intrinsic optical signal (IOS) in rat hippocampus
  • alone or in combination with sodium salicylate to study its effects on auditory responses in the rat′s dorsal cortex of rat
  • to study its effects on hepatocellular carcinoma cells (HCC)

Biological Activity

Selective, brain penetrant GABA B receptor antagonist (IC 50 = 34 μ M as measured in rat cortical membranes). Has higher affinity for postsynaptic versus presynaptic receptors.

Biochem/physiol Actions

CGP 35348 is a γ-aminobutyric acid-B (GABAB) receptor antagonist. It has a higher affinity towards post-versus presynaptic receptors that can penetrate the blood-brain barrier.

CGP 35348 Preparation Products And Raw materials

CGP 35348 Suppliers

Global( 39)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48465 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9268 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 China 8736 58 Inquiry
BOC Sciences USA 0 65 Inquiry
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 China 4659 58 Inquiry
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 China 11710 58 Inquiry
Tocris Bioscience +44 (0) 117 916 3333 United Kingdom 5729 77 Inquiry

CGP 35348 Spectrum

CGP 35348 (3-AMINOPROPYL)(DIETHOXYMETHYL)PHOSPHINIC ACID (3-Aminopropyl)(diethoxymethyl)phosphinic acid hydrate CGP 35348 hydrate P-(3-Aminopropyl)-P-(diethoxymethyl)phosphinic acid Phosphinic acid, (3-aminopropyl)(diethoxymethyl)- spatial learning,neuromuscular,neonatal damage,CGP-35348,brain penetrant,GABA Receptor,CGP35348,Gamma-aminobutyric acid Receptor,centrally,GABAB,CGP 35348,Inhibitor,γ-Aminobutyric acid Receptor,inhibit,active Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)- 123690-79-9 C8H20NO4P GABA/Glycine receptor GABA