CGP 52432

CGP 52432 Structure
CAS No.
139667-74-6
Chemical Name:
CGP 52432
Synonyms
P52432;CGP 52432;CGP52432 >=98% (HPLC);CGP 52432;CGP-52432;CGP 52432;(3-((3,4-dichlorobenzyl)amino)propyl)(diethoxymethyl)phosphinic acid;3-([[[(3,4-DICHLOROPHENYL)METHYL]AMINO]PROPYL] DIETHOXYMETHYL)PHOSPHINIC ACID;Phosphinic acid, P-[3-[[(3,4-dichlorophenyl)methyl]amino]propyl]-P-(diethoxymethyl)-;Inhibitor,CGP-52432,inhibit,Gamma-aminobutyric acid Receptor,CGP52432,GABA Receptor,γ-Aminobutyric acid Receptor
CBNumber:
CB8669551
Molecular Formula:
C15H24Cl2NO4P
Molecular Weight:
384.24
MOL File:
139667-74-6.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59

CGP 52432 Properties

Boiling point 544.4±50.0 °C(Predicted)
Density 1.258±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility H2O: soluble1mg/mL, clear (warmed)
pka 2.26±0.50(Predicted)
form powder
color white to beige
Water Solubility Soluble in water (10mM, gentle warming)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3

CGP 52432 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0593 CGP52432 ≥98% (HPLC) 139667-74-6 5MG ₹13726.1 2022-06-14 Buy
Sigma-Aldrich(India) SML0593 CGP52432 ≥98% (HPLC) 139667-74-6 25MG ₹54806.98 2022-06-14 Buy
Product number Packaging Price Buy
SML0593 5MG ₹13726.1 Buy
SML0593 25MG ₹54806.98 Buy

CGP 52432 Chemical Properties,Uses,Production

Uses

CGP52432 has been used as a γ-aminobutyric acid B (GABAB) antagonist:

  • to study its effects on the simulation of the onset of status epilepticus (SE) in mice
  • for voltage-clamp recording in mice neurons
  • to study its effects on the GABAB receptor-mediated neurotransmission in guinea pig hippocampus

Biological Activity

Potent, selective GABA B receptor antagonist (IC 50 = 85 nM).

Biochem/physiol Actions

CGP52432 participates in inhibiting the glycine overflow in the hippocampus.

CGP 52432 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 70)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd +86-86-22-87899925 +86-8618522618860 China 694 58 Inquiry
Alfa Chemistry United States 24072 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry

CGP 52432 Spectrum

3-([[[(3,4-DICHLOROPHENYL)METHYL]AMINO]PROPYL] DIETHOXYMETHYL)PHOSPHINIC ACID CGP 52432 CGP 52432;CGP-52432;CGP 52432 P52432 Phosphinic acid, P-[3-[[(3,4-dichlorophenyl)methyl]amino]propyl]-P-(diethoxymethyl)- CGP52432 >=98% (HPLC) (3-((3,4-dichlorobenzyl)amino)propyl)(diethoxymethyl)phosphinic acid Inhibitor,CGP-52432,inhibit,Gamma-aminobutyric acid Receptor,CGP52432,GABA Receptor,γ-Aminobutyric acid Receptor 139667-74-6 C15H24Cl2NO4P GABA/Glycine receptor GABA