ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Standard Substance >(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride
- CAS No.
- 101152-94-7
- Chemical Name:
- (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride
- Synonyms
- IXEL;F 2207;Dalcipran;TOLEDOMIN;cis-(+-)-d;MIDALCIPRAN;Milnacipran HCI;MILNACIPRAN HCL;Chiral Reagents;Milnacipran HCl (1)
- CBNumber:
- CB4423243
- Molecular Formula:
- C15H23ClN2O
- Molecular Weight:
- 282.81
- MOL File:
- 101152-94-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 179-1810C |
|---|---|
| Flash point | 9℃ |
| storage temp. | 2-8°C |
| solubility | H2O: 19 mg/mL |
| form | solid |
| color | white |
| Merck | 14,6194 |
| CAS DataBase Reference | 101152-94-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P310 | |||||||||
| Hazard Codes | Xn,T,F | |||||||||
| Risk Statements | 22-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 7-16-36/37-45 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GZ1014010 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29242990 | |||||||||
| Toxicity | LD50 orally in mice: 237 mg/kg (Bonnaud) | |||||||||
| NFPA 704 |
|
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride price More Price(2)
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Uses
Antidepressant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia.
General Description
Milnacipran, sold under the brand names Savella?, Ixel?, Dalcipran?, or Toledomin, is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the treatment of depression. In 2009, the US Food and Drug Administration (FDA) approved milnacipran for management of the chronic pain disorder fibromyalgia, making it only the third drug approved in the US for this indication besides duloxetine and pregabalin.
Biological Activity
Orally active 5-HT and noradrenalin re-uptake inhibitor (SNRI) (IC 50 values are 203 and 100 nM respectively) that displays no affinity at a range of other receptors. Causes adaptive changes to α 1 -adrenergic and 5-HT 2A serotonergic systems when administered repeatedly. Exhibits antidepressive and antinociceptive activities in vivo .
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 327)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TYNDAL LABS PVT LTD | +91-8008166674 +91-8008166674 | AndhraPradesh, India | 95 | 58 | Inquiry |
| Darsh PharmaChem Pvt Ltd | +91-9712983850 +91-9712983850 | Gujarat, India | 33 | 58 | Inquiry |
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Macleods Pharmaceuticals Limited | +91-2266762800 +91-2266762800 | Maharashtra, India | 116 | 58 | Inquiry |
| Centaur Pharmaceuticals Pvt Ltd | +912266499100 | Mumbai, India | 33 | 58 | Inquiry |
| Unichem Laboratories Ltd | +91-2266888333 +91-2266888333 | Maharashtra, India | 62 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| BDR Pharmaceuticals International Pvt Ltd | +91-2240560560 +91-7718884418 | Maharashtra, India | 206 | 58 | Inquiry |
| Shankus Pharmaceuticals | +91-9099080089 +91-9099080014 | Gujarat, India | 21 | 58 | Inquiry |
| Raks Pharma Pvt Ltd | +91-8924671555 +91-8924671555 | AndhraPradesh, India | 31 | 58 | Inquiry |
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101152-94-7
C15H22N2OHClC15H23ClN2O
C15H23ClN2O
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