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Saracatinib

Saracatinib Structure
CAS No.
379231-04-6
Chemical Name:
Saracatinib
Synonyms
CS-69;EOS-61866;saracatinib;Gemcabene Calcium;Saracatinib, >=98%;AZD0530 difuMarate;AZD0530(Saracatinib);Saracatinib (AZD0530);Saracatinib USP/EP/BP;TIANFUCHEM-- Saracatinib
CBNumber:
CB61518531
Molecular Formula:
C27H32ClN5O5
Molecular Weight:
542.03
MOL File:
379231-04-6.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

Saracatinib Properties

Melting point 84-89°C
Boiling point 671.2±55.0 °C(Predicted)
Density 1.348
storage temp. -20°C
solubility Soluble in DMSO (50 mg/ml) and ethanol (54 mg/mL with warming)
form solid
pka 7.55±0.10(Predicted)
color White
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338
NFPA 704
0
2 0

Saracatinib Chemical Properties,Uses,Production

Description

Saracatinib is a dual inhibitor of the tyrosine kinases c-Src and Abl (IC50 = 2.7 and 30 nM, respectively). It less effectively inhibits other receptor and non-receptor tyrosine kinases as well as assorted serine/threonine kinases. Saracatinib is orally available and blocks cell motility, migration, adhesion, invasion, proliferation, differentiation, and survival. Through its effects on c-Src, it reduces osteoclast bone resorption. Saracatinib also blocks denque virus RNA replication through its effect on Fyn kinase.

Chemical Properties

White Solid

Saracatinib Preparation Products And Raw materials

Raw materials

Preparation Products

Saracatinib Suppliers

Global( 182)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21668 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24330 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Sinoway Industrial co., ltd. 0592-5800732; +8613806035118 China 990 58 Inquiry
Supplier Advantage
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
Capot Chemical Co.,Ltd. 60
Henan Tianfu Chemical Co.,Ltd. 55
ATK CHEMICAL COMPANY LIMITED 60
BOC Sciences 58
CONIER CHEM AND PHARMA LIMITED 58
Dideu Industries Group Limited 58
AFINE CHEMICALS LIMITED 58
Sinoway Industrial co., ltd. 58

Saracatinib Spectrum

Saracatinib(379231-04-6)1HNMR

379231-04-6(Saracatinib)Related Search:

Acetonitrile Gefitinib Sunitinib Lapatinib Imatinib
2-Ethoxyethanol Kresoxim-methyl Phenetidine Methylparaben 1-Methylpiperazine
2-Ethoxyphenol Basic Violet 1 Diethoxymethyl acetate DIETHOXYMETHANE Ethoxyquin
Paraquat dichloride Dasatinib monohydrate Ethoxymethylenemalononitrile
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7-[2-[4-Methylpiperazin-1-yl]ethoxy]-5-[[tetrahydropyran-4-yl]oxy]-4-[[6-chloro-2,3-Methylenedioxyphenyl]aMino]quinazoline (S)-2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetaMide N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine Saracatinib (AZD0530) Saracatinib N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine Saracatinib, >=98% Gemcabene Calcium saracatinib N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine 4-(6-Chloro-2,3-methylenedioxyanilino)-7-(2-(4-methylpiperazin-1-yl)ethoxy)-5-tetrahydropyran-4-yloxyquinazoline 4-Quinazolinamine, N-(5-chloro-1,3-benzodioxol-4-yl)-7-(2-(4-methyl-1-piperazinyl)ethoxy)-5-((tetrahydro-2H-pyran-4-yl)oxy)- N-(5-Chloro-1,3-benzodioxol-4-yl)-7-(2-(4-methylpiperazin-1-yl)ethoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine N-(5-Chlorobenzo[d][1,3]dioxol-4-yl)-7-(2-(4-methylpiperazin-1-yl)ethoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine Saracatinib (AZD0530) AZD0530(Saracatinib) AZD0530 difuMarate N-(5-Chlorobenzo[d][1,3]dioxol-4-yl)-7-(2-(4-methylpiperazin-1-yl)ethoxy)-5-(tetrahydro-2H-pyr CS-69 AZD0530; AZD-0530; AZD 0530 EOS-61866 Saracatinib USP/EP/BP TIANFUCHEM-- Saracatinib Saracatinib AZD0530 AZD-0530 N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(oxan-4-yloxy)quinazolin-4-amine 379231-04-6 C27H32ClN5O5 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Protein Kinase Inhibitors and Activators APIs Inhibitors