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Dasatinib monohydrate

Dasatinib monohydrate Structure
CAS No.
863127-77-9
Chemical Name:
Dasatinib monohydrate
Synonyms
Sprycel;Dasatinib hydrate;mmbf;CS-295;Dastinib;Dasatinib R;Bms 35482503;Unii-rbz1571X5h;Dasatinib(TINIBS);Dasatinib(Sprycel)
CBNumber:
CB4844484
Molecular Formula:
C22H28ClN7O3S
Molecular Weight:
506.02
MOL File:
863127-77-9.mol
MSDS File:
SDS
Modify Date:
2024/6/19 22:55:17
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Dasatinib monohydrate Properties

Melting point >223° (dec.)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form Solid
color White to Off-White
Stability Hygroscopic
InChIKey XHXFZZNHDVTMLI-UHFFFAOYSA-N
SMILES N(C1=NC=C(C(=O)NC2C(=CC=CC=2C)Cl)S1)C1N=C(C)N=C(N2CCN(CCO)CC2)C=1.O
CAS DataBase Reference 863127-77-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS09,GHS06
Signal word  Danger
Hazard statements  H410-H300-H372-H361-H360
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P260-P264-P270-P314-P501-P273-P391-P501-P201-P202-P281-P308+P313-P405-P501
HS Code  29339900

Dasatinib monohydrate Chemical Properties,Uses,Production

Uses

Dasatinib Monohydrate is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. It is a COVID19-related research product.

Definition

Dasatinib monohydrate is a hydrate that is the monohydrate of dasatinib. It is used for the treatment of chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia. Note that the name 'dasatinib' is used to refer to the monohydrate (USAN； dasatinib monohydrate) as well as to anhydrous dasatinib (INN). It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It contains a dasatinib (anhydrous).

brand name

Sprycel (Bristol-Myers Squibb).

Dasatinib monohydrate Preparation Products And Raw materials

Raw materials

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide N-Deshydroxyethyl Dasatinib Dasatinib 4,6-Dichloro-2-methylpyrimidine
Dasatinib
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Preparation Products

Dasatinib monohydrate Suppliers

Global( 446)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Dr. Reddy's Laboratories Ltd +91-4049002900 +91-4049002900 Hyderabad, India 165 58 Inquiry
Salvavidas Pharmaceutical Pvt., Ltd. +91-2612538898 +91-9327127459 Gujarat, India 34 58 Inquiry
Basil Drugs AND Pharmaceuticals Pvt Ltd +91-2249700250 +91-9619320820 Mumbai, India 108 58 Inquiry
Beta Drugs +91-9316590666 +91-7015991921 Haryana, India 34 58 Inquiry
Vijaya Pharma And Life Science +91-8939866271 +91-8939866271 Tamil Nadu, India 320 58 Inquiry
MSN LABORATORIES PRIVATE LTD +91 40 30438600 New Delhi, India 230 58 Inquiry
DR REDDYS LABORATORIES LTD +91-40-49002900 New Delhi, India 201 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Mac-Chem Products (india) Pvt. Ltd. 08069023792Ext 810 Mumbai, India 2 58 Inquiry
Supplier Advantage
Dr. Reddy's Laboratories Ltd 58
Salvavidas Pharmaceutical Pvt., Ltd. 58
Basil Drugs AND Pharmaceuticals Pvt Ltd 58
Beta Drugs 58
Vijaya Pharma And Life Science 58
MSN LABORATORIES PRIVATE LTD 58
DR REDDYS LABORATORIES LTD 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Mac-Chem Products (india) Pvt. Ltd. 58

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Dasatinib R BMS-354825 Monohydrate N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide hydrate Dasatinib monohydrate N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide monohydrate Dasatinib monohydrate, >=99% dasatinib monohydrate 5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-, hydrate (1:1) Dasatinib(TINIBS) Dastinib Bms 35482503 Unii-rbz1571X5h n-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide monohydrate n-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide n-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2- CS-295 Dasatinib(Sprycel) N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide,hydrate asatinib monohydrate Dasatinib monohydrate USP/EP/BP DasatinibmonohydrateDasatinib Dasatinib Monohydrate (BMS354825 Dasatinib Monohydrate intermediate Dasatinib hydrate Sprycel mmbf Dashatini monohydrate Dasatinib (monohydrate) (Dasatinib Impurity) Dashatinib monohydrate 863127-77-9 863121-77-9 C22H26CIN7O2SH2O C22H26ClN7O2SH2O Inhibitors API Anti-cancer&immunity SPRYCEL Molecular Targeted Antineoplastic Pharmaceutical 863127-77-9