N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide

CAS No.: 302964-08-5

Chemical Name:: N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide

Synonyms: Dasatinib Int N-1;CAY10697;2-((6-ChL;)amino)-N-(2-chL;dasatinib Dichloro;Dasatinib Impurity M;Dasatinib EP Impurity-D;Dasatinib Intermediate 1;Dasatinib Dichloro Impurity;2-(6-Chloro-2-MethylpyriMidin-4-ylaMino)-N-(2-chloro-6-Methyl

CBNumber:: CB51473109

Molecular Formula:: C16H13Cl2N5OS

Molecular Weight:: 394.28

MOL File:: 302964-08-5.mol

MSDS File:: SDS

Modify Date:: 2024/3/28 13:50:01

Request For Quotation

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide Properties

Melting point	333-335°C
Boiling point	566.95° C (Predicted)
Density	1.516±0.06 g/cm3(Predicted)
refractive index	n20D 1.72 (Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	DMSO (Slightly)
pka	10.92±0.70(Predicted)
form	Solid
color	Pale Yellow
Water Solubility	Slightly soluble in water
InChI	InChI=1S/C16H13Cl2N5OS/c1-8-4-3-5-10(17)14(8)23-15(24)11-7-19-16(25-11)22-13-6-12(18)20-9(2)21-13/h3-7H,1-2H3,(H,23,24)(H,19,20,21,22)
InChIKey	LMXUWARKUIELGT-UHFFFAOYSA-N
SMILES	S1C(C(NC2=C(C)C=CC=C2Cl)=O)=CN=C1NC1C=C(Cl)N=C(C)N=1
CAS DataBase Reference	302964-08-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319

Precautionary statements

P261-P305+P351+P338

HS Code

2933399990

NFPA 704

	0
2		0

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemicals (India)	C3675	2-[(6-Chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide	302964-08-5	1G	₹2200	2022-05-26	Buy
TCI Chemicals (India)	C3675	2-[(6-Chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide	302964-08-5	5G	₹4800	2022-05-26	Buy

Product number	Packaging	Price	Buy
C3675	1G	₹2200	Buy
C3675	5G	₹4800	Buy

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide Chemical Properties,Uses,Production

Description

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide is a pharmaceutical intermediate compound used as a synthetic intermediate for dasatinib. Dasatinib is a targeted anticancer drug used to treat chronic myeloid leukaemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukaemia (ALL). It is also a receptor and non-receptor Tyk (tyrosine kinase) inhibitor, which plays an important role in certain cancers and fibrotic diseases.

Chemical Properties

Pale Yellow Solid

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide Preparation Products And Raw materials

Raw materials

Thiourea, N-(6-chloro-2-methyl-4-pyrimidinyl)- 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 4,6-Dichloro-2-methylpyrimidine

Preparation Products

Dasatinib

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide Suppliers

Global( 291)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
KROMOZOME	+91-91-9650900955 +91-09650900955	Maharashtra, India	71	58	Inquiry
GLP Pharma Standards	+91 9866074638	Hyderabad, India	1644	58	Inquiry
Besil Chem LLP	+91-7760252666 +91-9880731835	Bangalore, India	163	58	Inquiry
Vijaya Pharma And Life Science	+91-8939866271 +91-8939866271	Tamil Nadu, India	320	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
Trignokem International	+91 (40) 2717-0709	New Delhi, India	380	50	Inquiry
KKyemistry (India) Pvt. Ltd.	+91 (40) 2351-0950	New Delhi, India	197	50	Inquiry

Supplier	Advantage
KROMOZOME	58
GLP Pharma Standards	58
Besil Chem LLP	58
Vijaya Pharma And Life Science	58
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
SynZeal Research Pvt Ltd	58
Trignokem International	50
KKyemistry (India) Pvt. Ltd.	50

302964-08-5(N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide)Related Search:

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2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]- Dasatinib Intermediate 1 2-(6-Chloro-2-MethylpyriMidin-4-ylaMino)-N-(2-chloro-6-Methyl 2-[(6-chloro-2-MethylpyriMidin-4-yl)aMino]-N-(2-chloro-6-Methylphenyl)-1,3-thiazole-5-carboxaMide N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-yrimidinyl)amino]-5-thiazolecarboxamide N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino] CAY10697 N-(2-Chloro-6-methyl-phenyl)-2-[(6-chloro-2-methyl-pyrimidin-4-yl)amino]thiazole-5-carboxamide N-(2-CHLORO-6-METHYLPHENYL)-2-[(6-CHLORO-2-METHYL-4-PYRIMIDINYL)AMINO]-5-THIAZOLECARBOXAMIDE 2-[(6-Chloro-2-methyl-4-pyrimidyl)amino]-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide Dasatinib Dichloro Impurity )amino)-N-(2-chL 2-((6-ChL N- (2-chloro-6-methylphenyl) -2-[(6-chloro-2-methyl-4-pyrimidinyl) amino] -5-thiazole-formamide Dasatinib Impurity M N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidi... dasatinib Dichloro 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95% Dasatinib Int N-1 Dasatinib EP Impurity-D N - (2-chloro-6-methylphenyl) -2- [(6-chloro-2-methyl-4-pyrimidinyl) amino] -5-thiazolamide N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)ami]-5-thiazolecarboxamide 2-(6-Chloro-2-methyl-pyrimidin-4-ylamino)-thiazole-5-carboxylic acid (2-chloro-6-methyl-phenyl)-amide N-(2-Chloro-6-Methylphenyl)-2-[(6-chloro-2-Methyl-4-pyriMidinyl)aMino]-5-thiazolecarboxaMi 302964-08-5 2964-08-5 964-08-5 Dasatinib Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds