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Calcium 2-oxoglutarate

Calcium 2-oxoglutarate Structure
CAS No.
71686-01-6
Chemical Name:
Calcium 2-oxoglutarate
Synonyms
CALCIUM ALPHA-KETOGLUTARATE MONOHYDRATE;Ca AKG;Ca-ketoglutarate;Calcium Ketoglutarate;Calcium 2-oxoglutarate;Calcium 2-oxopentanedioate;a-Ketoglutaric acid calcium;α-ketoglutarate calcium salt;α-Ketoglutaric acid calcium salt;α-Ketoglutaric acid calcium salt
CBNumber:
CB4446033
Molecular Formula:
C5H8CaO5
Molecular Weight:
188.19
MOL File:
71686-01-6.mol
Modify Date:
2024/6/17 17:42:23

Calcium 2-oxoglutarate Properties

Melting point >300°C (not melting)
storage temp. -20°C, Hygroscopic
solubility Aqueous Acid (Slightly), Water (Slightly, Heated, Sonicated)
form Solid
color White to Off-White
Water Solubility Water: Insoluble
Stability Hygroscopic
InChI InChI=1S/C5H6O5.Ca.2H/c6-3(5(9)10)1-2-4(7)8;;;/h1-2H2,(H,7,8)(H,9,10);;;
InChIKey YWFUOMFSJDJVPT-UHFFFAOYSA-N
SMILES C(=O)(C(=O)O)CCC(=O)O.[Ca]
CAS DataBase Reference 71686-01-6(CAS DataBase Reference)

Calcium 2-oxoglutarate Chemical Properties,Uses,Production

Description

Calcium 2-oxoglutarate is a reversible tyrosinase inhibitor, an intermediate in the production of ATP or GTP in the Krebs cycle, and a major carbon skeleton for nitrogen assimilation reactions. It has a variety of biological roles and can be used as a precursor for the synthesis of glutamate, an enzyme involved in the synthesis of amino acids and fatty acids, involved in the transcriptional regulation of cells and influencing plant metabolism, among other roles. Recent studies have demonstrated that mitochondria-mediated calcium 2-oxoglutarate in the rat heart is capable of controlling the formation of aspartic acid.

Uses

Calcium 2-Oxoglutarate helps stabilie redox homeostasis and helps improve arterial elasticity.

Application

Calcium 2-oxoglutarate is the Calcium salt form of 2-oxoglutarate. 2-oxoglutarate is naturally found in organisms and is a well-known intermediate in the production of ATP or GTP in the Krebs cycle.

Biological Activity

Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. It also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC50=15 mM).

Calcium 2-oxoglutarate Preparation Products And Raw materials

Raw materials

Preparation Products

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ALPHA-KETOGLUTARATE CALCIUM MONOHYDRATE A-KETOGLUTARIC ACID, CALCIUM SALT, MONOHYDRATE Calcium 2-oxoglutarate Pentanedioic Acid ,2-oxo-,Calcium Salt α-Ketoglutaric acid calcium salt 2-Oxopentanedioic acid calcium salt Calcium 2-oxopentanedioate Ca-ketoglutarate Calcium Ketoglutarate Monohydrate Calcium Ketoglutarate α-Ketoglutaric acid calcium salt CALCIUM ALPHA-KETOGLUTARATE MONOHYDRATE Pentanedioic acid,2-oxo-, calcium salt (1:1) Ca AKG α-ketoglutarate calcium salt a-Ketoglutaric acid calcium 71686-01-6 C5H6O6CaC5H4O5CaH2O C5H4O5Ca C5H6O6Ca