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OUABAIN OCTAHYDRATE

OUABAIN OCTAHYDRATE Structure
CAS No.
11018-89-6
Chemical Name:
OUABAIN OCTAHYDRATE
Synonyms
Ouabain CRS;OUABAIN 8H2O;OUABAIN 8H20;G-Strophantin;STROPHANTHIN G;OUABAIN HYDRATE;OUBAIN OCTAHYDRATE;OUABAIN OCTAHYDRATE;(-)-OUABAIN OCTAHYDRATE;Ouabain octahydrate,96%
CBNumber:
CB4469924
Molecular Formula:
C29H60O20
Molecular Weight:
728.77
MOL File:
11018-89-6.mol
Modify Date:
2023/5/18 11:31:14

OUABAIN OCTAHYDRATE Properties

Melting point 260 °C
storage temp. room temp
solubility H2O: 10 mg/mL cold
form powder
color white
optical activity [α]25/D 31 to 32.5° in H2O(lit.)
Water Solubility Soluble in water.
Sensitive Light Sensitive
BRN 101712
Stability Stable for 2 years from date of purchase as supplied. Protect from exposure to moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
EPA Substance Registry System Card-20(22)-enolide, 3-[(6-deoxy-.alpha.-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, octahydrate, (1.beta.,3.beta.,5.beta.,11.alpha.)- (11018-89-6)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06,GHS08
Signal word  Danger
Hazard statements  H301+H331-H373
Precautionary statements  P301+P310+P330-P304+P340+P311-P314
Hazard Codes  T
Risk Statements  23/25-33
Safety Statements  45
RIDADR  UN 1544 6.1/PG 1
WGK Germany  3
RTECS  RN3850000
8
HazardClass  6.1(b)
PackingGroup  III
HS Code  29389090

OUABAIN OCTAHYDRATE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) O3125 Ouabain octahydrate ≥95% (HPLC), powder 11018-89-6 250MG ₹5239.3 2022-06-14 Buy
Sigma-Aldrich(India) O3125 Ouabain octahydrate ≥95% (HPLC), powder 11018-89-6 1G ₹15826.15 2022-06-14 Buy
Sigma-Aldrich(India) PHR1945 Ouabain Pharmaceutical Secondary Standard; Certified Reference Material 11018-89-6 300MG ₹15826.15 2022-06-14 Buy
Sigma-Aldrich(India) O3125 Ouabain octahydrate ≥95% (HPLC), powder 11018-89-6 5G ₹63196.35 2022-06-14 Buy
Sigma-Aldrich(India) O3125 Ouabain octahydrate ≥95% (HPLC), powder 11018-89-6 25G ₹208651.88 2022-06-14 Buy
Product number Packaging Price Buy
O3125 250MG ₹5239.3 Buy
O3125 1G ₹15826.15 Buy
PHR1945 300MG ₹15826.15 Buy
O3125 5G ₹63196.35 Buy
O3125 25G ₹208651.88 Buy

OUABAIN OCTAHYDRATE Chemical Properties,Uses,Production

Chemical Properties

white to off-white crystalline powder

Uses

Ouabain octahydrate, is used as a tool to induce in vivo excitotoxicity. Ouabain, as well as other endogenous digitalis-like compounds, can down-regulate the expression of 14-3-3 proteins in rat lens.

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Potential Exposure

Ouabain, similar to digitoxin, is used to produce rapid digitalization in acute congestive heart failure. Also recommended in treatment of atrial or nodal paroxysmal tachycardia and atrial flutter; enzyme inhibitor.

Shipping

UN1544 Alkaloids, solid, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Purification Methods

It crystallises from water as the octahydrate. Dry it at 130o. It decomposes at 190o when dry. Store it in the dark as it is light sensitive, but it is stable in air. Its solubility (g/100mL) in H2O is 1.3 (~25o), 20 (~100o), and in EtOH it is 1.0 (~25o) and 12.5 (~78o). It is highly TOXIC as it is an inhibitor of cation transport and of Na+ and K+ ATPase. [Beilstein 18/5 V 625.]

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.).

OUABAIN OCTAHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

OUABAIN OCTAHYDRATE Suppliers

Global( 113)Suppliers
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BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
ShangHai Anpel Co, Ltd. 18501792038; 18501792038 China 9614 58 Inquiry
Shaanxi kelkai Pharmaceutical Technology Co., Ltd 029-029-2148545164 17392779578 China 6576 58 Inquiry
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 China 30968 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9274 58 Inquiry
Ouabain octahydrate,96% Ouabain octahydrate,1β,3β,5β,11α,14,19-Hexahydroxycard-20(22)-enolide 3-(6-deoxy-α-L-mannopyranoside), Acocantherine, G-Strophanthin STROPHANTHIN G STROPHANTHIN G, OCTAHYDRATE OUABAIN 8H20 OUABAIN 8H2O OUABAIN HYDRATE (-)-OUABAIN OCTAHYDRATE OUABAIN OCTAHYDRATE OUBAIN OCTAHYDRATE 1β,3β,5β,11α,14,19-Hexahydroxycard-20(22)-enolide 3-(6-deoxy-α-L-mannopyranoside) Card-20(22)-enolide, 3-(6-deoxy-.alpha.-L-mannopyranosyl)oxy-1,5,11,14,19-pentahydroxy-, octahydrate, (1.beta.,3.beta.,5.beta.,11.alpha.)- Acocantherine, G-Strophanthin, 1β,3β,5β,11α,14,19-Hexahydroxycard-20(22)-enolide 3-(6-deoxy-α-L-mannopyranoside) Ouabain octahydrate, 96% 1GR G-Strophantin (1β,3β,5β,11α)-3-[(6-Deoxy-α-L-Mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxycard-20(22)-enolide Octahydrate G-STROPHANTHIN OCTAHYDRATE G-STROPHANTIN OCTAHYDRATE (1beta,3beta,5beta,11alpha)-3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-card-20(22)-enolide octahydrate Card-20(22)-enolide,3-[(6-deoxy-a-L-Mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-,hydrate (1:8), (1b,3b,5b,11a)- Ouabain octahydrate 96% Strophanthin glycosides G 1β,3β,5β,11α,14,19-Hexahydroxycard-20(22)-enolide 3-(6-deoxy-α-L-mannopyranoside) Acocantherine G-Strophanthin G-Strophantin octahydrate Ouabain, Octahydrate - CAS 11018-89-6 - Calbiochem Ouabain CRS Ouabain Octahydrate (Acocantherine) Card-20(22)-enolide, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, hydrate (1:8), (1β,3β,5β,11α)- (1β,3β,5β,11α)-3-[(6-deoxy-α-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-Card-20(22)-enolide hydrate (1:8) Na+/K+ ATPase,Ouabain,Sodium potassium pump,inhibit,Inhibitor,Autophagy,Ouabain octahydrate g-Strophanthin Octahydrate, ≥ 98.0% 11018-89-6 C29H44O128H2O C28H44O12x8H2O Ion Channels Lipids Other Sodium Channel Modulators Monovalent Ion Channels Sodium Channel Modulators Sterols Voltage-gated Ion Channels Conjugates Cell Signaling and Neuroscience BioChemical Biochemicals and Reagents Cell Biology Carbohydrates & Derivatives Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Steroids