PIMARIC ACID
- CAS No.
- 127-27-5
- Chemical Name:
- PIMARIC ACID
- Synonyms
- Pimaric;NSC 2956;PIMARIC ACID;Pimaric Acid (>DextropiMaric Acid;Δ8(14)-PiMaric Acid;Pimaric acid (PiMA);Pimaric Acid (> 75%);Hexazinone Impurity 27;8(14),15-PiMaradien-18-oic Acid
- CBNumber:
- CB4506393
- Molecular Formula:
- C20H30O2
- Molecular Weight:
- 302.45
- MOL File:
- 127-27-5.mol
- Modify Date:
- 2024/7/2 8:55:09
| Melting point | 217-219° |
|---|---|
| alpha | D18 +74.7° (c = 0.4 in chloroform); D20 +87.3° (in chloroform) |
| Boiling point | bp18 282° |
| Density | 1.0434 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| storage temp. | Store at -20°C |
| solubility | DMSO: soluble,Water: soluble |
| pka | 4.68±0.60(Predicted) |
| form | Solid |
| color | White to off-white |
| LogP | 6.731 (est) |
| EPA Substance Registry System | Pimaric acid (127-27-5) |
PIMARIC ACID Chemical Properties,Uses,Production
Description
Pimaric acid is a resin acid that has been found in A. cordata and various pines. It reduces mRNA expression, protein levels, and promoter activity of matrix metalloproteinase-9 (MMP-9) in TNF-α-stimulated human aortic smooth muscle cells (HASMCs) in a concentration-dependent manner when used at concentrations ranging from 5 to 20 μM. Pimaric acid (10-20 μM) reduces nuclear expression and binding of the transcription factors NF-κB and AP-1 to the MMP-9 promoter in HASMCs. Pimaric acid also reduces TNF-α-induced HASMC migration to control levels when used at a concentration of 20 μg/ml.
Uses
A novel activators of large-conductance Ca2+-activated K+ channel α-subunit.
PIMARIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 68)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29820 | 58 | Inquiry |
| LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33350 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | China | 40067 | 58 | Inquiry |
| Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
127-27-5(PIMARIC ACID)Related Search:
(1R,4aR,4bS,7S,10aR)-7-Ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-triMethyl-1-phenanthrenecarboxylic Acid
13α-Methyl-13-vinylpodocarp-8(14)-en-15-oic acid
PIMARIC ACID
1-phenanthrenecarboxylicacid,7-ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahyd
7-trimethyl-,[1theta-(1alpha,4abeta,4balpha,7beta,10aalpha)]-ro-4a
13-alpha-methyl-13-vinylpodocarp-8(14)-en-15-oic acid
1-Phenanthrenecarboxylic acid, 7-ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-trimethyl-, (1R,4aR,4bS,7S,10aR)-
8(14),15-PiMaradien-18-oic Acid
DextropiMaric Acid
NSC 2956
PiMara-8(14),15-dien-19-oic Acid
Δ8(14)-PiMaric Acid
Pimaric Acid (Contains 10-25% Sandaracopimaric Acid)
Pimaric Acid (>
Pimaric Acid (> 75%)
Pimaric
Hexazinone Impurity 27
Pimaric acid (PiMA)
127-27-5
Activators
Aliphatics
Chiral Reagents
Intermediates & Fine Chemicals
Pharmaceuticals