ChemicalBook > Product Catalog >Dyes and Pigments >dye >Azoic dyes >Naphthol AS-E

Naphthol AS-E

Naphthol AS-E Structure
CAS No.
92-78-4
Chemical Name:
Naphthol AS-E
Synonyms
nAS-E;C.I. 37510;Naftol AS-E;NAPTHOL AS-E;NAPHTHOL AS-E;Amarthol AS-E;DaitoGrounderE;AcnaNaphtholPC;Kiwa Grounder E;92-78-4 Naphthol AS-E
CBNumber:
CB4723659
Molecular Formula:
C17H12ClNO2
Molecular Weight:
297.74
MOL File:
92-78-4.mol
MSDS File:
SDS
Modify Date:
2023/6/8 17:06:35

Naphthol AS-E Properties

Melting point 255°C
Boiling point 416.5±30.0 °C(Predicted)
Density 1.399±0.06 g/cm3(Predicted)
vapor pressure 0Pa at 25℃
storage temp. Sealed in dry,Room Temperature
solubility soluble in Dimethylformamide
pka 8.69±0.40(Predicted)
Colour Index 37510
form Beige solid
color White to Light yellow to Dark green
LogP 2.97 at 23℃ and pH7.2
CAS DataBase Reference 92-78-4(CAS DataBase Reference)
EPA Substance Registry System 2-Naphthalenecarboxamide, N-(4-chlorophenyl)-3-hydroxy- (92-78-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P261-P264-P272-P280-P302+P352-P305+P351+P338
HS Code  2924.29.7790

Naphthol AS-E price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 217505 CBP-CREB Interaction Inhibitor - CAS 92-78-4 - Calbiochem The CBP-CREB Interaction Inhibitor, also referenced under CAS 92-78-4, controls the biological activity of CBP-CREB. 92-78-4 250MG ₹10709.99 2022-06-14 Buy
TCI Chemicals (India) C2103 4'-Chloro-3-hydroxy-2-naphthanilide 92-78-4 25G ₹5000 2022-05-26 Buy
Product number Packaging Price Buy
217505 250MG ₹10709.99 Buy
C2103 25G ₹5000 Buy

Naphthol AS-E Chemical Properties,Uses,Production

Preparation

4-Chlorobenzenamine and 3-Hydroxy-2-naphthoic acid condensation.

General Description

A cell-permeable naphthamide compound that effectively blocks the interaction between the KIX domain of CBP and the KID domain of CREB in HEK293T-based and cell-free Renilla luciferase (RLuc) complementation assays (IC50 = 2.26 and 2.9 M, respectively) by directly binding to CBP′s KIX domain (Kd ~8.6 M using a recombinant KIX). Shown to inhibit CRE- (cAMP response element) dependent transcription activity induced by forskolin in a HEK293T-based RLuc reporter assay (IC50<2.5 M), while exhibiting little effect against the KID-independent CREB-VP16 transcription activity. Also reported to inhibit the enzymatic activity of Firefly luciferase (IC50 ~1 M), but not that of RLuc.

Properties and Applications

light yellow microstrip red uniform powder, melting point for 258 ~ 259 ℃. Insoluble in water solution and sodium carbonate, soluble in adjacent two chlorobenzene, ethanol and glacial acetic acid. Sodium hydroxide solution for yellow in the liquid. Sensitive to air. Mainly used for cotton fabrics, viscose and silk dyeing, general is not used for printing, and can be used as organic pigments intermediate. This product to cotton affinity is higher, coupled ability medium.

Naphthol AS-E Preparation Products And Raw materials

Global( 177)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Bhagwati Industries +91-9909249884 +91-9909249884 Gujarat, India 89 58 Inquiry
Jagson Colorchem Limited +91-9879484214 +91-9879484214 Gujarat, India 318 58 Inquiry
Vipul Organics Ltd +91-2266139999 +91-2266139999 Maharashtra, India 277 58 Inquiry
Jaffs Dyechem Private Limited +91-9825035135 +91-7925392314 Gujarat, India 309 58 Inquiry
Aarnee International 91-79-40055406 Gujarat, India 20 58 Inquiry
Textile Colour and Chemical (Exports) 91-79-26575821 Gujarat, India 38 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Emco Dyestuff Private Limited 08048372738Ext 428 Mumbai, India 15 58 Inquiry
Daikaffil Chemicals (India) Limited +91 22 2353 0325 Maharashtra, India 6 58 Inquiry
Om Impex 08048371895Ext 259 Maharashtra, India 35 58 Inquiry
NAPHTHOL AS-E NAPTHOL AS-E N-(4-CHLOROPHENYL)-3-HYDROXY-2-NAPHTHAMIDE c.i. azoic coupling component 10 AZOIC COUPLING COMPONENT 10 4'-CHLORO-3-HYDROXY-2-NAPHTHANILIDE AcnaNaphtholPC DaitoGrounderE n-(4-chlorophenyl)-3-hydroxy-2-naphthalenecarboxamid 2-Hydroxy-3-Naphthoyl-p-Chloraniline 2-Naphthalenecarboxamide-N-(4-chlorophenyl)-3-hydroxy 4′-Chlor-3-hydroxy-2-naphthanilid Naphthol AS-E (C.I. 37510) 4''-CHLORO-3-HYDROXY-2-NAPHTHANILIDE 97.0+%(T) C.I. 37510 Amarthol AS-E Kiwa Grounder E Naftol AS-E CBP-CREB Interaction Inhibitor N-(4-Chlorophenyl)-3-hydroxynaphthalene-2-carboxamide N-(4-Chlorophenyl)-3-hydroxy-2-naphthamide Naphthol AS-E Azoic Coupling Component 10 nAS-E N-(4-Chlorophenyl)-3-hydroxy-2-naphthalenecarboxamide CBP-CREB Interaction Inhibitor - CAS 92-78-4 - Calbiochem 4'-Chloro-3-hydroxy-2-naphthanilide > Naphthol AS-E ISO 9001:2015 REACH Naphthol AS-E (4'-Chloro-3-hydroxy-2-naphthanilide) C.I.Azoic Coupling Component 10:C.I.37510 92-78-4 Naphthol AS-E 4'-Chloro-3-hydroxy-2-naphthanilide 92-78-4 AMINE Substrates Intermediates of Dyes and Pigments