Metolazone
- CAS No.
- 17560-51-9
- Chemical Name:
- Metolazone
- Synonyms
- DIULO;MYKROX;Zaroxolyn;Xuret;OLDREN;microx;s720-22;METENIX;Normelan;fonamide
- CBNumber:
- CB4725936
- Molecular Formula:
- C16H16ClN3O3S
- Molecular Weight:
- 365.83
- MOL File:
- 17560-51-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 9:02:57
| Melting point | 252-254°C |
|---|---|
| Boiling point | 613.6±65.0 °C(Predicted) |
| Density | 1.2895 (rough estimate) |
| refractive index | 1.6100 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO: >5mg/mL |
| pka | pKa 9.7 (Uncertain) |
| form | solid |
| color | white |
| Water Solubility | 60.3mg/L(25 ºC) |
| Stability | Stable for 2 years as supplied. Solutions in DMSO may be stored desiccated at -20°C for up to 2 months. |
| InChIKey | AQCHWTWZEMGIFD-UHFFFAOYSA-N |
| CAS DataBase Reference | 17560-51-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Metolazone(17560-51-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | VA1700000 | |||||||||
| HS Code | 2935904000 | |||||||||
| Toxicity | LD50 in mice (mg/kg): >5000 orally; >1500 i.p. (Shetty, 1967) | |||||||||
| NFPA 704 |
|
Metolazone price More Price(2)
Metolazone Chemical Properties,Uses,Production
Description
Metolazone (Item No. 26304) is an analytical reference standard categorized as a diuretic. It has been detected as an adverse analytical finding (AAF) during anti-doping testing. This product is intended for use in analytical forensic applications. This product is also available as a general research tool .
Chemical Properties
Crystalline Solid
Uses
Metolazone acts on the distal tubules, thus increasing excretion of water and sodium, potassium, and chloride ions. It is used for treating edema caused by cardiac insufficiency and adrenal irregularities, including nephrotic syndrome.
Definition
ChEBI: A quinazoline that consists of 1,2,3,4-tetrahydroquinazolin-4-one bearing additional methyl, 2-tolyl, sulfamyl and chloro substituents at positions 2, 3, 6 and 7 respectively. A quinazoline diuretic, with properties similar to thiazide diuretics.
Metolazone Preparation Products And Raw materials
Global( 167)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| KARPSCHEM LABORATORIES | +91-7249203006 +91-7249203006 | Maharashtra, India | 786 | 58 | Inquiry |
| Centaur Pharmaceuticals Pvt Ltd | +912266499100 | Mumbai, India | 33 | 58 | Inquiry |
| Biophore India Pharmaceuticals Pvt Ltd | +91-9100031592 +91-9030907714 | Telangana, India | 134 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| MSN LIFE SCIENCES PRIVATE LTD | +91 84523 34200 | New Delhi, India | 104 | 58 | Inquiry |
| CENTAUR PHARMACEUTICALS PRIVATE LTD | +91 22 – 66499100 | New Delhi, India | 17 | 58 | Inquiry |
| BIOPHORE INDIA PHARMACEUTICALS PVT LTD | +91-4047474545 | New Delhi, India | 105 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
17560-51-9(Metolazone)Related Search:
s720-22
7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide, SR-720-22, Diulo, Metenix, Mykrox, Oldren,
6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo- (9CI)
6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl- (8CI)
Normelan
Xuret
6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro- 2-methyl-3-(2-methylphenyl)-4-oxo-
METAZOLINE
7-CHLORO-2-METHYL-4-OXO-3-O-TOLYL-1,2,3,4-TETRAHYDROQUINAZOLINE-6-SULFONAMIDE
Metolazone【hypotensive drug】
Metolazone,7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide
Metolazone (200 mg)
OLDREN
SR-720-22
METOLAZONE
METENIX
1,2,3,4-tetrahydro-7-chloro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamid
2-methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone
6-quinazolinesulfonamide,7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylpheny
7-CHLORO-1,2,3,4-TETRAHYDRO-2-METHYL-3-(2-METHYLPHENYL)-4-OXO-6-QUINAZOLINESULFONAMIDE
Metolazone(Zaroxolyn)
Metozalone
Metolazone, >=99%
7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesul
7-chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamid
7-chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-tolyl-6-quinazolinesulfonamide
fonamide
l)-4-oxo-
metalozone
microx
6-quinazolinesulfonamide,7-chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-toly
7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolines
Metolazone CRS
Metolazone for system suitability CRS
Metolazone USP/EP/BP
Metolazone (SR-720-22)
Metolazone D7Q: What is
Metolazone D7 Q: What is the CAS Number of
Metolazone D7 Q: What is the storage condition of
Metolazone D7
Metolazone API
Metolazone (1441200)
Zaroxolyn
MYKROX
DIULO
17560-51-9
Voltage-gated Ion Channels
Sodium Channel Modulators
Ion Channels
Other Sodium Channel Modulators
Monovalent Ion Channels
BioChemical
Cell Signaling and Neuroscience
Cell Biology
ZAROXOLYN
Other APIs
Organics
Amines
Aromatics
Heterocycles
Sulfur & Selenium Compounds