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GALANTHAMINONE

GALANTHAMINONE Structure
CAS No.
510-77-0
Chemical Name:
GALANTHAMINONE
Synonyms
Narwedine;(4aS;8aS)-;Narwedin);-Narwedine;(-)-Narwedine;Galantaminone;GALANTHAMINONE;(-)-Narwedine 99.8% min;GALANTHAMINONE Impurity
CBNumber:
CB4774651
Molecular Formula:
C17H19NO3
Molecular Weight:
285.34
MOL File:
510-77-0.mol
Modify Date:
2024/7/2 8:55:09

GALANTHAMINONE Properties

Melting point 175-180°C (dec.)
Boiling point 397.4±42.0 °C(Predicted)
Density 1.28±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility DMSO : 10 mg/mL (35.05 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form Cryst.
pka 7.84±0.20(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H331-H301
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501

GALANTHAMINONE Chemical Properties,Uses,Production

Description

This alkaloid occurs in several families of the Amaryllidaceae and is obtained as colourless prisms when crystallized from Me2CO. It is dextrorotatory with [α]25D + 100° (c 0.2, CHC13). It forms a crystalline picrate, m.p. 123°C; a methiodide, m.p. 195-6°C and a semicarbazone, indicative of a keto group, m.p. 240-1 °c (dec.).

Chemical Properties

White to Off-White

Uses

A metabolite of Galanthamine, a selective acetylcholinesterase inhibitor

References

Boit, Dapke, Beitner., Chem. Ber., 90,2197 (1957)

GALANTHAMINONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 153)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20296 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Xi'an Kono chem co., Ltd., 029-86107037 13289246953 China 2995 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
SIMAGCHEM CORP +86-13806087780 China 17367 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418671 China 34571 58 Inquiry

GALANTHAMINONE Spectrum

GALANTHAMINONE (4aS 8aS)- (4aS,8aS)-4a,5,9,10,11,12-Hexahydro-3-Methoxy-11-Methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one GalantaMine interMediate ((-)-Narwedine) GalantaMinone (GalantaMine IMpurity A) 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-one,4a,5,9,10,11,12-hexahydro-3-Methoxy-11-Methyl-, (4aS,8aS)- Galanthaminone Narwedine Galantamine Hydrobromide Lycoremine (4AS,8aS)-3-methoxy-11-methyl-9,10,11,12-tetrahydro-4aH-benzo[2,3]benzofuro[4,3-cd]azepin-6(5H Galantamine EP impurity A -F Narwedin) Galantamine EP impurity A N6-p-Methoxyphenyladenosin (-)-Narwedine 99.8% min Galantamine Impurity 1(Galantamine EP Impurity A) (-)-Narwedine Galnthaminone Narwedin Galantamine EP Impurity A (Galantaminone) (-)-Narwedine Galantaminone GALANTHAMINONE USP/EP/BP Galantamine hydrobromide EP Impurity A (4AS,8aS)-3-methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-one Narwedine (4aS,8aS)-3-methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-[1]benzofuro[3a,3,2-ef][2]benzazepin-6-one (narwedine) Narwedine (6CI, 7CI, 8CI) -Narwedine (-)-Narwedine Galnthaminone Narwedin GALANTHAMINONE Impurity 510-77-0 19453 1953/4/4 raw materials Various Metabolites and Impurities Heterocycles Intermediates & Fine Chemicals Metabolites Pharmaceuticals