ChemicalBook > Product Catalog >Organic Chemistry >Amides >Naphthenic amines derivatives >4-Iodoaniline

4-Iodoaniline

CAS No.: 540-37-4

Chemical Name:: 4-Iodoaniline

Synonyms: BENZENAMINE, 4-IODO-;P-IODOANILINE;4-iodobenzenamine;4-IodoaniL;4-LODANILINE;4-IODOANILINE;4-iodo-anilin;p-iodo-anilin;Iodine aniline;4-Indo Aniline

CBNumber:: CB5110557

Molecular Formula:: C6H6IN

Molecular Weight:: 219.02

MOL File:: 540-37-4.mol

MSDS File:: SDS

Modify Date:: 2024/9/19 18:11:18

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4-Iodoaniline Properties

Melting point	61-63 °C(lit.)
Boiling point	268.7±23.0 °C(Predicted)
Density	1.8155 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	H2O: slightly soluble
form	Crystalline Powder or Needles
pka	3.81(at 25℃)
color	Beige to grayish-brown
Water Solubility	Slightly soluble in water.Soluble in chloroform, methanol.
Sensitive	Light Sensitive
Merck	14,5027
BRN	774101
InChIKey	VLVCDUSVTXIWGW-UHFFFAOYSA-N
CAS DataBase Reference	540-37-4(CAS DataBase Reference)
NIST Chemistry Reference	Benzenamine, 4-iodo-(540-37-4)
EPA Substance Registry System	Benzenamine, 4-iodo- (540-37-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P264-P270-P301+P312-P302+P352-P305+P351+P338

Hazard Codes

Xn,Xi

Risk Statements

22-36/37/38-20/21/22

Safety Statements

26-36/37/39-36

RIDADR

2811

WGK Germany

RTECS

BY3850000

Hazard Note

Harmful/Irritant

TSCA

HazardClass

6.1(b)

PackingGroup

III

HS Code

29214210

NFPA 704

	1
2		1

4-Iodoaniline price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	129364	4-Iodoaniline 98%	540-37-4	25G	₹5250	2022-06-14	Buy
Sigma-Aldrich(India)	129364	4-Iodoaniline 98%	540-37-4	100G	₹8952.28	2022-06-14	Buy
ALFA India	ALF-B21936-30	4-Iodoaniline, 98%	540-37-4	250g	₹13380	2022-05-26	Buy
ALFA India	ALF-B21936-18	4-Iodoaniline, 98%	540-37-4	50g	₹4573	2022-05-26	Buy
TCI Chemicals (India)	I0048	4-Iodoaniline min. 99.0 %	540-37-4	25G	₹4600	2022-05-26	Buy

Product number	Packaging	Price	Buy
129364	25G	₹5250	Buy
129364	100G	₹8952.28	Buy
ALF-B21936-30	250g	₹13380	Buy
ALF-B21936-18	50g	₹4573	Buy
I0048	25G	₹4600	Buy

4-Iodoaniline Chemical Properties,Uses,Production

Chemical Properties

beige to greyish-brown crystalline powder. soluble in alcohol, ether and chloroform, slightly soluble in water.

Uses

4-Iodoaniline is a iodine substituted aniline that is widely used as chemical intermediates in the manufacturing of pesticides, dyes and drugs. 4-Iodoaniline was shown to be a more potent nephrotoxica nt in vitro than other anilines.

Preparation

4-Iodoaniline is obtained by the reaction of aniline and iodine in the presence of sodium bicarbonate. Add aniline and sodium bicarbonate to water and slowly add crushed iodine in stages with vigorous stirring. If the reaction solution is yellow, add a little sodium bisulfite to make it discolor, then filter and get the crude product. Then the product is recrystallized by ethanol to obtain 4-Iodoaniline.

General Description

4-Iodoaniline is the most potent methaemoglobin former.

Purification Methods

Crystallise it from pet ether (b 60-80o) by refluxing, then cool it in an ice-salt bath freezing mixture. Dry it in air. Alternatively, crystallise it from EtOH and dry it in vacuo for 6hours at 40o [Edidin et al. J Am Chem Soc 109 3945 1987]. The N-acetyl derivative has m 184o (from MeOH). [Beilstein 12 IV 1544.]

4-Iodoaniline Preparation Products And Raw materials

Raw materials

Sodium bisulfite

Preparation Products

4-ETHYNYLANILINE N-(4-THIOPHEN-2-YL-PHENYL)-ACETAMIDE 4,4'-Dithiodianiline 4,4'-THIODIANILINE 4-Isopropylaniline

4-Aminobenzoic acid 4-Phenoxyaniline 1-Iado-4-(trifluoromethoxy)benzene 4'-AMINOBUTYROPHENONE 3'-METHOXY-BIPHENYL-4-YLAMINE HYDROCHLORIDE

3'-FLUORO-BIPHENYL-4-YLAMINE HYDROCHLORIDE 4'-CHLORO-BIPHENYL-4-YLAMINE 5-iodo-1-methylindoline-2,3-dione 4'-DIETHYLAMINOPHENYL ACETYLENE Benzenamine, 4-(1-naphthalenyl)-

4-Iodo-N,N-dimethyl-Benzenamine 4-IODO-N-METHYLANILINE 4-(2-METHOXYETHOXY)ANILINE

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4-Iodoaniline Suppliers

Global( 554)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
BTC pharm India	+918790379245	AndhraPradesh, India	1269	58	Inquiry
GLR Innovations	+91 9891111994	New Delhi, India	4542	58	Inquiry
Seema Finechem Industry LLP	+91-8451840941 +91-8451840941	NaviMumbai, India	43	58	Inquiry
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Infinium Pharmachem Limited	+91-2692238849 +91-2692238850	Gujarat, India	65	58	Inquiry
LAURICE LABS	+91-9820672480 +91-9820672480	Maharashtra, India	40	58	Inquiry

Supplier	Advantage
BTC pharm India	58
GLR Innovations	58
Seema Finechem Industry LLP	58
Dynarx Technology India Limited	58
SURVIVAL TECHNOLOGIES LIMITED	58
Sarex Overseas	58
SRIGEN LIFE SCIENCES PVT LTD	58
Laksh Finechem Pvt.Ltd.	58
Infinium Pharmachem Limited	58
LAURICE LABS	58

4-Iodoaniline Spectrum

4-Iodoaniline(540-37-4)MS 4-Iodoaniline(540-37-4)¹HNMR 4-Iodoaniline(540-37-4)¹³CNMR 4-Iodoaniline(540-37-4)IR1 4-Iodoaniline(540-37-4)IR2 4-Iodoaniline(540-37-4)IR3 4-Iodoaniline(540-37-4)IR 4-Iodoaniline(540-37-4)Raman 4-Iodoaniline(540-37-4)ESR

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1-amino-4-iodobenzene 4-IODOANILINE 4-LODANILINE 4-iodo-anilin 4-iodo-benzenamin 4-iodo-Benzenamine 1-Iodo-4-aminobenzene p-Aminoiodobenzene 4-Aminophenyl iodide 4-Iodoaniline,99% 4-IodobenzeneaMine 4-Iodoaniline, 99% 25GR The iodine aniline Iodine aniline 4-Iodoaniline≥ 98% (GC) 4-Iodo-phenylamine Aniline, 4-iodo- Aniline, p-iodo- Benzenamine,4-Iodoaniline p-Aminophenyl iodide p-aminophenyliodide p-iodo-anilin 4-Indo Aniline IODOANILINE, 4- 4-Iodoaniline,~98% 4-IodoaniL 4-Iodoaniline, 98%, for synthesis 4-Iodoaniline> 4 - iodine aniline 4-Iodoaniline ISO 9001：2015 REACH BENZENAMINE, 4-IODO- P-IODOANILINE 4-iodobenzenamine p－lodoaniline RSYY(Apremilast)-8 4 Iodoaniline (P-Iodoaniline,4-Iodobenzenamine) 4-iodoaniline (4-iodoaniline) 540-37-4 IC6H4NH2 IC6H6N C2 to C6 Building Blocks Amines AMINE Organic Building Blocks Nitrogen Compounds Building Blocks C6 Chemical Synthesis Nitrogen Compounds Organic Building Blocks Pharmaceutical Intermediates Anilines, Aromatic Amines and Nitro Compounds Amines API intermediates Anilines, Amides & Amines Iodine Compounds C2 to C6