ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Aromatics >(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol Structure
CAS No.
127852-28-2
Chemical Name:
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol
Synonyms
C1oHgF6O;R-MBT-PEL;(R)-1-[3,5-Bis(trifL;Aprepitant Impurity 49;Phenol,5-iodo-4-methyl-;Rolapitant Intermediate 3;Fosaprepitant Impurity 25;Thiazole,2-bromo-9-methyl-;(R)-1-[3,5- Bis(trifluoromethyl)phenyl]et;(R)-BIS-3,5-TRIFLUOROMETHYL-1-PHENYLETHANOL
CBNumber:
CB5113482
Molecular Formula:
C10H8F6O
Molecular Weight:
258.16
MOL File:
127852-28-2.mol
MSDS File:
SDS
Modify Date:
2025/3/3 9:06:10

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol Properties

Melting point 53-58℃
Boiling point 175.8±35.0 °C(Predicted)
Density 1.376±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Acetonitrile (Slightly), Chloroform (Slightly)
pka 13.99±0.20(Predicted)
form Powder
color White
optical activity [α]/D +27±1°, c = 1 in acetonitrile
λmax 272nm(MeOH)(lit.)
InChIKey MMSCIQKQJVBPIR-RXMQYKEDSA-N
CAS DataBase Reference 127852-28-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H302-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-52/53-22
Safety Statements  26-36/37/39-61
WGK Germany  3
Hazard Note  Irritant
HS Code  29062990
NFPA 704
1
2 0

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 49554 (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol ≥98.0% (GC) 127852-28-2 5G ₹6743.98 2022-06-14 Buy
Sigma-Aldrich(India) 49554 (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol ≥98.0% (GC) 127852-28-2 25G ₹19192.73 2022-06-14 Buy
TCI Chemicals (India) B4131 (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol min. 98.0 % 127852-28-2 5G ₹5500 2022-05-26 Buy
TCI Chemicals (India) B4131 (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol min. 98.0 % 127852-28-2 25G ₹14500 2022-05-26 Buy
ALFA India ALF-H60893-06 (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol, 98% 127852-28-2 5g ₹6585 2022-05-26 Buy
Product number Packaging Price Buy
49554 5G ₹6743.98 Buy
49554 25G ₹19192.73 Buy
B4131 5G ₹5500 Buy
B4131 25G ₹14500 Buy
ALF-H60893-06 5g ₹6585 Buy

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol Chemical Properties,Uses,Production

Chemical Properties

White fine crystalline powder

General Description

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol is a key intermediate for the synthesis of aprepitant, a potent human neurokinin-1 (NK-1) receptor.

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 439)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Vardhaman P Golechha 9704422000 Telangana, India 292 58 Inquiry
BASF India Limited +91-2262785600 +91-2262785600 Maharashtra, India 209 58 Inquiry
TEADUS PHARMA PRIVATE LIMITED +91-9740077663 +91-9740077663 Telangana, India 242 58 Inquiry
JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6905 58 Inquiry
Reax Chemicals 08048372701Ext 416 Hyderabad, India 4217 58 Inquiry
Ms Life Sciences 08048372386Ext 826 Hyderabad, India 341 58 Inquiry
New Rise Life Science 91-8790905328 Hyderabad, India 150 58 Inquiry

Related articles

(R)-BIS-3,5-TRIFLUOROMETHYL-1-PHENYLETHANOL (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol,99%e.e. (R)-1-[3,5-BIS(TRIFLUORO-METHYL)-PHENYL]ETHANOL 98% (1R)-1-[3,6-BIS(TRIFLUOROMETHYL)PHENYL]ETHANOL R-MBT-PEL (R)-1-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)ETHAN-1-OL (R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHANOL (R)-1-[BIS-3,5-(TRIFLUOROMETHYL)PHENYL]ETHANOL Benzenemethanol, a-methyl-3,5-bis(trifluoromethyl)-, (aR)- (1R)-(+)-1-[3,5-Bis(trifluoromethyl)phenyl]ethan-1-ol (R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethanol >=98.0% (GC) Benzenemethanol, .alpha.-methyl-3,5-bis(trifluoromethyl)-, (.alpha.R)- (R)-1-[3,5-Bis(trifluoromethyl) phenyl]ethanol,Aprepitant intermediate Rolapitant Intermediate 3 (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol127852-28-2 Fosaprepitant Impurity 25 Aprepitant Impurity 49 (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol (Aprepitant) (R)-1-[3,5-Bis(trilfuoromethyl)phenyl]ethanol (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol > (R)-1-[3,5-di (trifluoromethyl) phenyl] ethanol (R)-1-[3,5-Bis(trifL Benzenemethanol, α-methyl-3,5-bis(trifluoromethyl)-, (αR)- (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl Alcohol (R)-3,5-Bis(trifluoromethyl)-alpha-methylbenzyl Alcohol Aprepitant intermediates,(R)-1-[3,5- Bis(trifluoromethyl)phenyl]ethanol ?-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol, 98%, (R)-1-[3,5-Bis(trifluoromethyl)phenyi]ethanol Thiazole,2-bromo-9-methyl- Phenol,5-iodo-4-methyl- Benzenemethanol,α-methyl-3,5-bis(trifluoromethyl)-,(αR)- (S)-1-(3,5-Bi(trifluoromethyl)phenyl)ethan-1-ol (αR)-α-Methyl-3,5-bis(trifluoromethyl)benzenemethanol (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)-benzenemethanol C1oHgF6O (R)-l-(3,5-bis(trifluorom ethyl)pheny l)ethan-1 -ol (R)-1-[3,5- Bis(trifluoromethyl)phenyl]et (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol 127852-28-2 C10H8F7O C10H8OF6 API intermediates Alcohols, Hydroxy Esters and Derivatives Chiral Compounds 127852-28-2