ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Nitropyridine >2-Methyl-5-nitropyridine
2-Methyl-5-nitropyridine
- CAS No.
- 21203-68-9
- Chemical Name:
- 2-Methyl-5-nitropyridine
- Synonyms
- AURORA KA-6797;5-NITRO-2-PICOLINE;2-Methyl-5-nitropyri;2-METHYL-5-NITROPYRIDINE;5-Nitro-2-methylpyridine;2-Methy1-5-nitropyridine;Pyridine, 2-methyl-5-nitro-;2-Methyl-5-nitropyridine>2-Methyl-5-nitropyridine 95%;2-METHYL-5-NITROPYRIDINE, 95+%
- CBNumber:
- CB5130896
- Molecular Formula:
- C6H6N2O2
- Molecular Weight:
- 138.12
- MOL File:
- 21203-68-9.mol
- Modify Date:
- 2024/4/8 16:27:35
Melting point | 112 C |
---|---|
Boiling point | 237.1±20.0 °C(Predicted) |
Density | 1.246±0.06 g/cm3(Predicted) |
storage temp. | Inert atmosphere,Room Temperature |
pka | 1.92±0.10(Predicted) |
form | Solid |
color | Light yellow to Brown |
Water Solubility | Slightly soluble in water. |
InChI | InChI=1S/C6H6N2O2/c1-5-2-3-6(4-7-5)8(9)10/h2-4H,1H3 |
InChIKey | USZINSZJSVMICC-UHFFFAOYSA-N |
SMILES | C1(C)=NC=C([N+]([O-])=O)C=C1 |
CAS DataBase Reference | 21203-68-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
HS Code | 2933399990 | |||||||||
NFPA 704 |
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2-Methyl-5-nitropyridine price More Price(2)
2-Methyl-5-nitropyridine Chemical Properties,Uses,Production
Uses
2-Methyl-5-nitropyridine is used as pharmaceutical intermediate.
Synthesis
2-(5-nitro-pyridin-2-yl)-malonic acid diethyl ester could be used as a starting material to synthesize 2-methyl-5-nitropyridine. The specific operations are as follows: To 2-(5-nitro-pyridin-2-yl)-malonic acid diethyl ester (12.0 g, 42.5 mmol) was added cold aq. 20% sulfuric acid (120 mL) and the mixture was heated to 100 ℃ for 2h. The cooled reaction was added to a cold dilute sodium hydroxide solution and the pH adjusted to 10. The organics were extracted with dichloromethane (x 4), and then the combined organic phases were dried over sodium sulfate. The filtrate was concentrated to afford 2-methyl-5-nitropyridine (5.0 g, 83 %) as a brown solid.
2-Methyl-5-nitropyridine Preparation Products And Raw materials
Raw materials
5-nitro-2-phenylpyrimidine
2'-Hydroxy-4'-methyl-5'-acetylacetophenone
1-METHYL-5-NITRO-2(1H)-PYRIMIDINONE
2-Methyl-3-nitropyridine
2-Chloro-3-nitro-6-methylpyridine
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Global( 303)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED | +919966658228 | Hyderabad, India | 486 | 58 | Inquiry |
CHATURYA BIOTECH | +91-7702707258 +91-7702707258 | Telangana, India | 479 | 58 | Inquiry |
TANUJ PYRIDINE | 8790371027 | Hyderabad, India | 107 | 58 | Inquiry |
Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
Clarity Research Laboratory | +91-8008229325 +91-8008229325 | Telangana, India | 96 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6700 | 30 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
S.R.LABORATORIES | +914027177083 | New Delhi, India | 148 | 30 | Inquiry |
PNP Biotech Co. Ltd | +8618516098983 | China | 1001 | 58 | Inquiry |
Supplier | Advantage |
---|---|
ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED | 58 |
CHATURYA BIOTECH | 58 |
TANUJ PYRIDINE | 58 |
Rivashaa Agrotech Biopharma Pvt. Ltd. | 58 |
Clarity Research Laboratory | 58 |
CHEMSWORTH | 30 |
A.J Chemicals | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
S.R.LABORATORIES | 30 |
PNP Biotech Co. Ltd | 58 |
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