ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Pyridine derivatives >2,2'-Dithiodipyridine

2,2'-Dithiodipyridine

CAS No.: 2127-03-9

Chemical Name:: 2,2'-Dithiodipyridine

Synonyms: 1,2-Di(pyridin-2-yl)disulfane;Aldrithiol;2-Aldrithiol;2-PDS;Dithiodipyridine;ALDRITHIOL-2;Dipyridyldisulfide;2-Pyridyl disulfide;1,2-Bis(2-pyridinyl) Disulfide;2PDS

CBNumber:: CB5200205

Molecular Formula:: C10H8N2S2

Molecular Weight:: 220.31

MOL File:: 2127-03-9.mol

MSDS File:: SDS

Modify Date:: 2025/4/24 21:50:42

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2,2'-Dithiodipyridine Properties

Melting point	56-58 °C(lit.)
Boiling point	356.1±17.0 °C(Predicted)
Density	1.3078 (rough estimate)
refractive index	1.5500 (estimate)
Flash point	210 °C
storage temp.	2-8°C
solubility	methanol: soluble50mg/mL, clear to very slightly hazy, colorless to faintly brownish-yellow
pka	1.52±0.19(Predicted)
form	powder
color	Clear colorless to yellow to tan
Water Solubility	5 g/L (20 ºC)
BRN	154629
InChIKey	HAXFWIACAGNFHA-UHFFFAOYSA-N
LogP	2.530 (est)
CAS DataBase Reference	2127-03-9(CAS DataBase Reference)
NIST Chemistry Reference	Pyridine, 2,2'-dithiobis-(2127-03-9)
EPA Substance Registry System	Pyridine, 2,2'-dithiobis- (2127-03-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-37-20/22

Safety Statements

36/37/39-37/39-25-22-36-26

RIDADR

UN 3335

WGK Germany

10-23

Autoignition Temperature

340 °C

Hazard Note

Irritant

TSCA

Yes

HS Code

29333990

NFPA 704

	0
2		0

2,2'-Dithiodipyridine price More Price(16)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	D5767	2,2′-Dithiodipyridine powder	2127-03-9	1G	₹2522.23	2022-06-14	Buy
Sigma-Aldrich(India)	D5767	2,2′-Dithiodipyridine powder	2127-03-9	5G	₹6484.18	2022-06-14	Buy
Sigma-Aldrich(India)	D5767	2,2′-Dithiodipyridine powder	2127-03-9	25G	₹24616.05	2022-06-14	Buy
Sigma-Aldrich(India)	8.41109	2,2′-Dipyridyl disulfide for synthesis	2127-03-9	5G	₹9510	2022-06-14	Buy
Sigma-Aldrich(India)	143049	Aldrithiol™-2 98%	2127-03-9	1G	₹1634.58	2022-06-14	Buy

Product number	Packaging	Price	Buy
D5767	1G	₹2522.23	Buy
D5767	5G	₹6484.18	Buy
D5767	25G	₹24616.05	Buy
8.41109	5G	₹9510	Buy
143049	1G	₹1634.58	Buy

2,2'-Dithiodipyridine Chemical Properties,Uses,Production

Chemical Properties

white to yellowish crystalline powder

Uses

2,2'-Dipyridyldisulfide, sometimes known as DPS, is used for preparing thiols and activating or protecting carboxylic acid with triphenylphosphine.

Uses

2,2'-Dithiodipyridine was used in the synthesis of adenosine-5′-phosphoimidazolide. It was employed with PPh₃ as a condensing agent in the amidation of carboxylic acid enantiomers for HPLC separation.

General Description

2,2'-Dithiodipyridine is a nucleocapsid zinc finger targeting compound and can abrogate the infectivity of human immunodeficiency virus type-1 virions. It is a thiol reagent.

Purification Methods

Recrystallise the disulfide H2O from *C6H6/pet ether (6:7), ligroin or *C6H6. The picrate has m 119o (from EtOH). [Walter et al. Justus Liebigs Ann Chem 695 7785 1966, Marckwald et al. Chem Ber 33 1556 1900, Brocklehurst & Little Biochem J 133 67,78 1973, Beilstein 21 III/IV 48.] It has been used as a 1mM solution in EtOH for the spectrophotometric estimation of thiols. Essentially the thiol displaces half the disulfide molecule liberating the 2-mercaptopyridine anion, thereby shifting the from 340nm (of the disulfide) to 268nm (of the anion) at pH 9, or 278nm in H2O. (Compare

2,2'-Dithiodipyridine Preparation Products And Raw materials

Raw materials

Pyrithione Bispyrithione

Preparation Products

Finasteride PYRIDINE-2-SULFONYL CHLORIDE Pyridine,2-(2-propen-1-ylthio)- 2-Pyridinesulfonamide(6CI,7CI,9CI) 2-Methylthiopyridine

2-(ethenesulfonyl)pyridine

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2,2'-Dithiodipyridine Suppliers

Global( 354)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6700	30	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6100	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6768	58	Inquiry
Alfa Aesar	1 800 209 7001	Maharashtra, India	6905	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39927	58	Inquiry
Shijiazhuang Jianxin Biotechnology Co., LTD	+undefined-86-1906231316-9 +undefined86-19062313169	China	712	58	Inquiry
Hebei Yanxi Chemical Co., Ltd.	+8617531153977	China	5854	58	Inquiry
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	China	18137	58	Inquiry
Anhuyan (Hainan) Biotechnology Co., LTD	+8618163349544	China	2764	58	Inquiry
Moxin Chemicals	+8617320513646	China	9684	58	Inquiry

Supplier	Advantage
CHEMSWORTH	30
A.J Chemicals	58
TCI Chemicals (India) Pvt. Ltd.	58
Alfa Aesar	58
Chongqing Chemdad Co., Ltd	58
Shijiazhuang Jianxin Biotechnology Co., LTD	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Anhuyan (Hainan) Biotechnology Co., LTD	58
Moxin Chemicals	58

2,2'-Dithiodipyridine Spectrum

2,2'-Dithiodipyridine(2127-03-9)MS 2,2'-Dithiodipyridine(2127-03-9)¹HNMR 2,2'-Dithiodipyridine(2127-03-9)¹³CNMR 2,2'-Dithiodipyridine(2127-03-9)IR1 2,2'-Dithiodipyridine(2127-03-9)Raman

2127-03-9(2,2'-Dithiodipyridine )Related Search:

2,5-PYRIDINEDICARBOXYLIC ACID Diallyldisulfide Dimethyl disulfide THIODIGLYCOLIC ACID 2,2'-Bipyridine

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Pyridine Dibenzyl disulfide 2,6-Lutidine Allicin

2,2'-DITHIOBIS(5-NITROPYRIDINE) 6,6'-DITHIODINICOTINIC ACID Bispyrithione 4,4'-DITHIODIPYRIDINE,4,4Dipyridyldisulfide-(4,4dithiodipyridine) GGKPDLRPCHPPCHYIPRPKPR

2,2'-Dithiodipyridine 4,4'-DIPYRIDYL DISULPHIDE, (4,4'-DITHIODIPYRIDINE) DI[5-(TRIFLUOROMETHYL)-2-PYRIDYL] DISULFIDE

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Bis(2-pyridyl) disulfide Di-2-Pyridyl disulfide Nsc 677438 Pyridine, 2,2'-dithiodi- ALDRITHIOL(TM)-2 2,2'-DIPYRIDYL DISULPHIDE 2-(PYRIDIN-2-YLDITHIO)PYRIDINE 2-PYRIDINYL DISULFIDE 2,2'-Dipyridyl Disulfide [for Peptide Synthesis] Pyridine, 2,2-dithiobis- 2,2''-DIPYRIDYL DISULFIDE 98+% NSC 94055 2,2'-Disulphanediyldipyridine, 2,2'-Dithiodipyridine Di(pyridin-2-yl) disulphide Aldrithiol(TM)-2 98% 1,2-Di(pyridin-2-yl)disulfide 2-(2-Pyridinyldisulfanyl)pyridine 2,2'-Dipyridinyl disulfide 2,2'-Dithiobis(pyridine) 2,2'-Dithiopyridine 2-Dipyridyl disulfide 2PDS Aldrithol-2 2,2'-Dithiodipyridine, >=99% Bis(pyridin-2-yl) disulfide 2,2μ-Dipyridyl disulfide, 2,2μ-Dithiodipyridine Aldritiol Di(2-pyridyl) persulfide 2,2'-Dithiodipyridine,98% 2,2'-Dithiodipyridin Bis(pyridin-2-yl) disulphide 2,2'- Dipyridil disulfide 2-(pyridin-2-yldisulfanyl)pyridine 2,2'-Bipyridyldisulfide Bis(2-pyridinyl) disulfide 2,2'-Dipyridyl disulfide, 98%, for synthesis 2,2'-DipyridylDisulfide[forPeptideSynthesis]> 2,2'-DIPYRIDYL DISULFIDE FOR SYNTHESIS 2,2'-Dithiodipyridine ISO 9001：2015 REACH 2-(2-Pyridyldisulfanyl)pyridine 9-[(3aS,6aR)-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-3H-purin-6-one Di(pyridin-2-yl) disulfide 1,2-Di(pyridin-2-yl ALDRITHIOL-2 2-PDS Dipyridyldisulfide 1,2-Di(pyridin-2-yl)disulfane 2-Pyridyl disulfide Aldrithiol Dithiodipyridine 1,2-Bis(2-pyridinyl) Disulfide 2-Aldrithiol 2,2'-Dithiodipyridine 2,2'-Dipyridyl disulfide 2,2'-Dipyridyl disulfide|||OPSS|||Aldrithiol 2|||Orthopyridyl disulfide 2,2''-Dithiodipyridine 2,2'-Dithiodipyridin Aldrithiol^?-2