ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >PI3K / Akt / mTOR >PI3K inhibitor >BAY 80-6946 (Copanlisib)
BAY 80-6946 (Copanlisib)
- CAS No.
- 1032568-63-0
- Chemical Name:
- BAY 80-6946 (Copanlisib)
- Synonyms
- Copanlisib;BAY80-6946;CS-2321;Aliqopa);Copanlisib base;Copanlisib free base;Copanlisib(BAY80-6946);BAY 80-6946 (BAY80-6946;BAY 80-6946 (Copanlisib);BAY 80-6946 (Copanlisib) USP/EP/BP
- CBNumber:
- CB52616024
- Molecular Formula:
- C23H28N8O4
- Molecular Weight:
- 480.52
- MOL File:
- 1032568-63-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:11
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| NFPA 704 |
|
BAY 80-6946 (Copanlisib) Chemical Properties,Uses,Production
brand name
Aliqopa
General Description
Class: lipid kinase; Treatment: FL (IV infusion); Other name: BAY 80-6946; Elimination half-life = 52 h (IV); Protein binding = 84.2%
Pharmacokinetics
Copanlisib has poor oral bioavailability due to low permeability and poor solubility, and therefore, it is not suitable for an oral medication. Consequently, it was developed as an IV drug. IV infusion of copanlisib resulted in rapid distribution throughout the body and a prolonged elimination half-life (52 h).
target
pan-PI3K
Metabolism
Copanlisib was the predominant component in
human plasma, accounting for 84% of total
radioactivity AUC, and the morpholinone metabolite
6 was the only circulating metabolite (about 5%).
BAY 80-6946 (Copanlisib) Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 148)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21676 | 55 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
1032568-63-0(BAY 80-6946 (Copanlisib))Related Search:
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2-Amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-5-pyrimidinecarboxamide
5-Pyrimidinecarboxamide, 2-amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-
Copanlisib(BAY80-6946)
BAY 80-6946 (Copanlisib)
7-methoxy-8-(3-morpholinopropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine
Aliqopa)
BAY 80-6946 (Copanlisib) USP/EP/BP
Copanlisib free base
BAY 80-6946; BAY80-6946; BAY-80-6946; BAY806946; BAY-806946; BAY 806946; COPANLISIB FREE BASE
CS-2321
BAY 80-6946 (BAY80-6946
Copanlisib base
Copanlisib, 98%, an ATP-competitive selective class-I PI3 kinases inhibitor
BAY80-6946
Copanlisib
2-Amino-N-(7-methoxy-8-(3-morpholinopropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)pyrimidine-5-carboxamide
1032568-63-0
C23H28N8O4
Inhibitors
Akt
mTOR
PI3K
PI3K/Akt/mTOR