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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >PI3K / Akt / mTOR >PI3K inhibitor >BKM120 (NVP-BKM120, Buparlisib)

BKM120 (NVP-BKM120, Buparlisib)

BKM120 (NVP-BKM120, Buparlisib) Structure
CAS No.
944396-07-0
Chemical Name:
BKM120 (NVP-BKM120, Buparlisib)
Synonyms
isib;100821;CS-227;BuparL;AN-2025;Buparlisib;BKM120BASE;NVP-BKM-120;BKM120, >=98%;NVP-BKM120, BKM120
CBNumber:
CB82509983
Molecular Formula:
C18H21F3N6O2
Molecular Weight:
410.39
MOL File:
944396-07-0.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:00
Request For Quotation

BKM120 (NVP-BKM120, Buparlisib) Properties

Melting point 143-147°C
Boiling point 645.7±65.0 °C(Predicted)
Density 1.382
storage temp. -20°C
solubility Soluble in DMSO (15 mg/ml)
form White powder.
pka 5.94±0.50(Predicted)
color White
Stability Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS06
Signal word  Danger
Hazard statements  H372-H341-H301
Precautionary statements  P260-P264-P270-P314-P501-P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501
HS Code  29349990
NFPA 704
0
2 0

BKM120 (NVP-BKM120, Buparlisib) Chemical Properties,Uses,Production

Uses

A selective Class I PI3K inhibitor of p110α, p110β, p110δ and p110γ with IC50s of 50-300 nM.

BKM120 (NVP-BKM120, Buparlisib) Preparation Products And Raw materials

Raw materials

Preparation Products

BKM120 (NVP-BKM120, Buparlisib) Suppliers

Global( 208)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Zhengzhou Alfa Chemical Co.,Ltd +8618530059196 China 13164 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Capot Chemical Co.,Ltd. 60
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
BOC Sciences 58
Chongqing Chemdad Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
Zhengzhou Alfa Chemical Co.,Ltd 58
TargetMol Chemicals Inc. 58

BKM120 (NVP-BKM120, Buparlisib) Spectrum

BKM120 (NVP-BKM120, Buparlisib)(944396-07-0)1HNMR

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5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine 5-(2,6-diMorpholinopyriMidin-4-yl)-4-(trifluoroMethyl)pyridin-2-aMine BKM120 (NVP-BKM120) NVP-BKM-120 BKM120 (NVP-BKM120, Buparlisib) NVP-BKM120, Buparlisib BKM120BASE Buparlisib BKM-120 4-(2,6-diMorpholinopyriMidin-4-yl)-3-(trifluoroMethyl)aniline 5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine BKM120 (NVP-BKM120, Buparlisib) NVP-BKM-120 5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine NVP-BKM120, BKM120 BKM120, >=98% BKM120 (Buparlisib) 5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine BKM120 2-Pyridinamine, 5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)- 5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine AN-2025 100821 CS-227 NVP-BKM120,Buparlisib,BKM120, >98% NVP-BKM-120; BKM-120; BUPARLISIB Buparlisib, 98%, a selective PI3K inhibitor Buparlisib (BKM120, NVP-BKM120) NVP-BKM-120; BKM-120;BUPARLISIB;BKM120;BKM 120 BuparL isib BKM120 (NVP-BKM120, Buparlisib) USP/EP/BP NVP-BKM120，Buparlisib，BKM120 944396-07-0 C18H21F3N6O2 C18H21O2N6F3 Akt mTOR PI3K Inhibitors Inhibitor API