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5,6-Dichloronicotinic acid

5,6-Dichloronicotinic acid Structure
CAS No.
41667-95-2
Chemical Name:
5,6-Dichloronicotinic acid
Synonyms
2,3-dichloropyridine-5-carboxylic acid;5,6-DichL;5,6-Dichloro;TIMTEC-BB SBB003623;5,6-DICHLORONICOTINIC A;Avatrombopag Impurity 10;Avatroposide impurities16;5,6-DICHLORONICOTINIC ACID;5,6-DichloronicotinicAcid>5,6-Dichloronicotinic acid 97%
CBNumber:
CB5261891
Molecular Formula:
C6H3Cl2NO2
Molecular Weight:
192
MOL File:
41667-95-2.mol
MSDS File:
SDS
Modify Date:
2024/5/16 10:38:37

5,6-Dichloronicotinic acid Properties

Melting point 164-168 °C(lit.)
Boiling point 342.1±37.0 °C(Predicted)
Density 1.612±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka 2.87±0.10(Predicted)
form Powder
color White to beige to tan
BRN 383740
InChI InChI=1S/C6H3Cl2NO2/c7-4-1-3(6(10)11)2-9-5(4)8/h1-2H,(H,10,11)
InChIKey RNRLTTNKVLFZJS-UHFFFAOYSA-N
SMILES C1=NC(Cl)=C(Cl)C=C1C(O)=O
CAS DataBase Reference 41667-95-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339900
NFPA 704
1
2 0

5,6-Dichloronicotinic acid price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 340219 5,6-Dichloropyridine-3-carboxylic acid 96% 41667-95-2 5G ₹7057.9 2022-06-14 Buy
TCI Chemicals (India) D2401 5,6-Dichloronicotinic Acid min. 97.0 % 41667-95-2 5G ₹4200 2022-05-26 Buy
TCI Chemicals (India) D2401 5,6-Dichloronicotinic Acid min. 97.0 % 41667-95-2 25G ₹15800 2022-05-26 Buy
Product number Packaging Price Buy
340219 5G ₹7057.9 Buy
D2401 5G ₹4200 Buy
D2401 25G ₹15800 Buy

5,6-Dichloronicotinic acid Chemical Properties,Uses,Production

Chemical Properties

white to off-white crystalline powder

Uses

5,6-Dichloronicotinic acid is a dihalonicotinic acid. It is used in the preparation of 5-chloro-6-iodonicotinic acid by iodine displacement.

Application

5,6-Dichloronicotinic acid is a compound that can be synthesized by reacting methyl ketones with chloroacetic acid. It is used in the synthesis of maleic anhydride and has been shown to inhibit the catalysis of acetylcholine chloride. It has also been shown to have an inhibitory effect on Alzheimer's disease. The kinetic mechanism for this inhibition occurs through the hydrolysis step of 5,6-Dichloronicotinic acid by magnesium chloride in hexane solution. The reactive acylation reaction proceeds when it reacts with acetic anhydride in the presence of pyridine.

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5,6-DICHLORO-3-PYRIDINECARBOXYLIC ACID 5,6-DICHLORONICOTINIC ACID 5,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID TIMTEC-BB SBB003623 5,6-Dichloropyridine-3-carboxylicacid,96% 5,6-Dichloro 5,6-DICHLORONICOTINIC ACID 98+% 5,6-Dichloronicotinic acid, 5,6-Dichloropyridine-3-carboxylic acid 5,6-Dichloropyridine-3-carboxylic acid, 98+% 5,6-Dichloropyridine-3-carboxylic acid, 5-Carboxy-2,3-dichloropyridine 5,6-Dichloronicotinic acid 97% 5,6-DichloronicotinicAcid> 5,6-DichL 3-Pyridinecarboxylic acid, 5,6-dichloro- Avatrombopag Impurity 10 5,6-Dichloronicotinic acid ISO 9001:2015 REACH 5,6-DICHLORONICOTINIC A 2,3-dichloropyridine-5-carboxylic acid Avatroposide impurities16 (4-cyclohexylpiperazin-1-yl)(5,6-dichloropyridin-3-yl)methanone 41667-95-2 1667-95-2 Pyridines Heterocyclic Building Blocks Halogenated Heterocycles Building Blocks Chloropyridines Halopyridines Heterocycle-Pyridine series Chloropyridines Halopyridines Pyridine Building Blocks C5 to C6 C6 to C7 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Pyridines pharmacetical Organic acids Pyridines, Pyrimidines, Purines and Pteredines Intermediate