6-Aminonicotinic acid
- CAS No.
- 3167-49-5
- Chemical Name:
- 6-Aminonicotinic acid
- Synonyms
- 3-Pyridinecarboxylic acid, 6-amino-;6- aMinoacid;6-AMinonicotinic a;TIMTEC-BB SBB004186;RARECHEM AL BO 1167;6-Aminonicotinc Acid;6-AMINONICOTINIC ACID;Nicotinic acid, 6-amino-;2-Amino-5-carboxypyridine;6-Aminonicotinic acid 98%
- CBNumber:
- CB9449781
- Molecular Formula:
- C6H6N2O2
- Molecular Weight:
- 138.12
- MOL File:
- 3167-49-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/8 20:25:11
Melting point | >300 °C (lit.) |
---|---|
Boiling point | 253.51°C (rough estimate) |
Density | 1.3471 (rough estimate) |
refractive index | 1.5100 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
form | Powder |
pka | 2.86±0.10(Predicted) |
color | White to beige |
Water Solubility | ca 1.0 g/L (20 ºC) |
Merck | 14,456 |
BRN | 115992 |
CAS DataBase Reference | 3167-49-5(CAS DataBase Reference) |
NIST Chemistry Reference | Nicotinic acid, 6-amino-(3167-49-5) |
EPA Substance Registry System | 3-Pyridinecarboxylic acid, 6-amino- (3167-49-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi,T | |||||||||
Risk Statements | 36/37/38-23/24/25 | |||||||||
Safety Statements | 22-24/25-45-36/37/39-26 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | T | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29333990 | |||||||||
NFPA 704 |
|
6-Aminonicotinic acid price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 216879 | 6-Aminopyridine-3-carboxylic acid 97% | 3167-49-5 | 1G | ₹2641.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 216879 | 6-Aminopyridine-3-carboxylic acid 97% | 3167-49-5 | 1G | ₹2641.3 | 2022-06-14 | Buy |
Sigma-Aldrich | 216879 | 6-Aminopyridine-3-carboxylic acid 97% | 3167-49-5 | 5G | ₹6083.65 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 216879 | 6-Aminopyridine-3-carboxylic acid 97% | 3167-49-5 | 5G | ₹6083.65 | 2022-06-14 | Buy |
TCI Chemicals (India) | A1486 | 6-Aminonicotinic Acid | 3167-49-5 | 1G | ₹3000 | 2022-05-26 | Buy |
6-Aminonicotinic acid Chemical Properties,Uses,Production
Chemical Properties
Light yellow Cryst
Uses
6-Aminopyridine-3-carboxylic acid (6-Aminonicotinic acid) was used in the preparation of resin-bound 2-aminoazine.
Definition
ChEBI: An aminonicotinic acid in which the amino group is situated at position 6 of the pyridine ring.
Application
6-Aminonicotinic acid is an inhibitor of bacterial DNA gyrase and topoisomerase IV. It has been shown to inhibit the growth of a number of bacteria, including E. coli K-12, with potent inhibitory activity against these enzymes. It binds to the active sites on these enzymes and prevents them from working. The detection time for 6-aminonicotinic acid is about 3 hours after exposure. It has been shown to be more potent than other inhibitors of bacterial DNA gyrase and topoisomerase IV such as 2,4-diaminopyrimidine (2,4DAP).
General Description
Electrosynthesis of 6-aminopyridine-3-carboxylic acid (6-aminonicotinic acid) by electrochemical reduction of 2-amino-5-bromo and 2-amino-5-chloropyridine in the presence of CO2 at silver electrode has been reported.
Purification Methods
Crystallise the acid from aqueous acetic acid. Dry it in vacuo at 70o. [Beilstein 22 III/IV 6726.]
6-Aminonicotinic acid Preparation Products And Raw materials
Raw materials
1of4
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Dr R R Organics | +91-9666306440 +91-9666306440 | Telangana, India | 267 | 58 | Inquiry |
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Dr. R.R. Organics | 91-9666306440 | Mallapur, India | 200 | 58 | Inquiry |
Supplier | Advantage |
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Dr R R Organics | 58 |
Prodev Pharma Pvt Ltd | 58 |
JSK Chemicals | 58 |
Vyas Bio Life Sciences Pvt. Ltd | 58 |
Novasyn Organics Pvt. Ltd (India) | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Alfa Aesar | 58 |
Anand Agencies | 58 |
Reax Chemicals | 58 |
Dr. R.R. Organics | 58 |