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3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide

3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide Structure
CAS No.
420831-40-9
Chemical Name:
3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide
Synonyms
AK-7;CS-922;AK 7, >=98%;AK-7;AK7;AK 7;SIRT2 Inhibitor II;SIRT2 Inhibitor,AK-7;SIRT2 Inhibitor II, AK-7;SIRT2 INHIBITOR II;AK7;AK 7;3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide;N-(3-Bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]-benzamide
CBNumber:
CB52639218
Molecular Formula:
C19H21BrN2O3S
Molecular Weight:
437.35
MOL File:
420831-40-9.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide Properties

Density 1.469±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility DMSO: ≥15mg/mL
form powder
pka 12.28±0.70(Predicted)
color white to tan
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
WGK Germany  3
NFPA 704
0
2 0

3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0152 AK-7 ≥98% (HPLC) 420831-40-9 5MG ₹10879.13 2022-06-14 Buy
Sigma-Aldrich(India) SML0152 AK-7 ≥98% (HPLC) 420831-40-9 25MG ₹44046.93 2022-06-14 Buy
Product number Packaging Price Buy
SML0152 5MG ₹10879.13 Buy
SML0152 25MG ₹44046.93 Buy

3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide Chemical Properties,Uses,Production

Description

The sirtuin SIRT2 is a deacetylase which targets α-tubulin, histone 4, forkhead transcription factors, and several other substrates. It has roles in metabolic diseases, cancer, age-related disorders, and neurodegenerative diseases, potentially including Alzheimer’s, Huntington’s, and Parkinson’s diseases. AK-7 is a cell- and brain-permeable inhibitor of SIRT2 (IC50 = 15.5 μM). In culture, it diminishes neuronal cell death induced by mutant huntingtin fragment. In addition, AK-7 down-regulates cholesterol biosynthetic gene expression and reduces total cholesterol levels in neurons in vivo.

3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide Preparation Products And Raw materials

Raw materials

Preparation Products

3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide Suppliers

Global( 104)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32835 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30250 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Coresyn Pharmatech Co., Ltd. +86-571-86626709 +86-18157142896 China 9991 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Shanghai Beckham Medical Technology Co., Ltd 021-13816613772 13816613772 China 418 55 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
BOC Sciences 58
Career Henan Chemica Co 58
InvivoChem 58
Coresyn Pharmatech Co., Ltd. 58
TargetMol Chemicals Inc. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Aladdin Scientific 58
Amadis Chemical Company Limited 58
Shanghai Beckham Medical Technology Co., Ltd 55

420831-40-9(3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide)Related Search:

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N-(3-Bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]-benzamide SIRT2 Inhibitor,AK-7 N-(3-Bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]-benzamide SIRT2 Inhibitor,AK-7 AK 7, >=98% 3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide AK-7 Benzamide, N-(3-bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]- AK-7;AK7;AK 7 SIRT2 Inhibitor II, AK-7 CS-922 SIRT2 INHIBITOR II;AK7;AK 7 SIRT2 Inhibitor II 420831-40-9